Bashiri Lab
@BashiriLab
Microbial Biochemistry and Biotechnology laboratory @AucklandUni @ScienceUoA. #AntimicrobialResistance #MethaneMitigation RT & Like ≠ endorsements
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Online now! Allosteric regulation of fungal fatty acid synthesis dlvr.it/TNQwwJ
Mycobacterium tuberculosis growth arrest on propionate at acidic pH is suppressed by mutations in phoPR and pyrazinamide treatment biorxiv.org/content/10.110…
Thrilled to share our latest paper now out in @ScienceMagazine 🎉🤩 We investigated a century of plasmid evolution 🧬 and uncovered how they have adapted to the antibiotic era 💊 science.org/doi/10.1126/sc…
How the twin-arginine translocase (Tat) system manages to transport folded proteins across membranes without any leaks? To answer this fundamental question we solved the first structure of TatB3C3 complex with bound cargo. Please check out new preprint! biorxiv.org/content/10.110…
Attending Queenstown Research Week? Join @CARB_X Chief Scientific Officer Richard Alm, PhD, for his presentation “CARB-X – Accelerating the Development of Novel Products to Tackle AMR.” 📆 Wednesday, September 3 ⏰ 3:30 PM NZST
Out Now! Deep learning reveals antibiotics in the archaeal proteome bit.ly/4lpohMM #DeepLearning #ArtificialIntelligence #Antibiotics
Here’s our latest biosynthetic study on swainsonine, nature.com/articles/s4158… — a pathway far more complex than expected and packed with enzymes brimming with synthetic potential. Led by our fantastic postdoc, @shaonan_liu, who will soon be starting his own lab in Shenzhen!
Join @CARB_X Chief Scientific Officer Richard Alm, PhD at a @MTPConnect_AUS panel discussing innovation in antibiotic R&D, sharing insights on translating AMR research into real-world solutions. 📆 Monday, July 14 ⏰ 12 – 2 PM ACST 🔗 Register now: bit.ly/4kWKp1x
If you have 30 minutes or so, listen to my recently finished honours student Sarah talking about her project. plantandfood.com/en-nz/article/…
A recent @OpenAccessGov piece by Melissa Gong Mitchell of @AMRAlliance highlighted the urgent need to fix the broken antibiotic R&D pipeline and the role of push incentives like @CARB_X in driving early-stage R&D. 🔗 Read more: bit.ly/43ZWj3e #AMR #StopSuperbugs
Introducing Bonnie Murphy, Ville Kaila, Maxie Roessler, Volha Chukhutsina, Alisia Fadini, Sonya Hanson, Filipe Maia, and Kirill Kovalev dlvr.it/TKbj4s
Thrilled to share our work that reveals unusual biosynthetic machinery for the core architecture of radarin indole-diterpenoids! Check out the incredibly complex cyclisation chemistry by the noncanonical terpene cyclase RadB.😊 @Ferrier_Inst @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Non-Canonical Type II Terpene #Cyclases Deliver Rare Terpenoid Architectures by Rose M. McLellan (@Dr_Rose_Gold), Daniel Berry, Rosannah C. Cameron, and Emily J. Parker at @Ferrier_Inst in @J_A_C_S pubs.acs.org/doi/10.1021/ja…
Our website is now up and running harrislab.co.nz with gratitude to my good friend Chris at mighty.nz
Chemical genetic interactions elucidate pathways controlling tuberculosis antibiotic efficacy during infection | PNAS pnas.org/doi/10.1073/pn…
Dear 🌱🧬 community, I am excited to share that I am recruiting PhD students for my lab at SBS, University of Auckland 🇳🇿! Our research will focus on the temperature regulation of the circadian clock in the legume M. truncatula, see comments below. Thanks for sharing!
In a year with so little to cheer about so far, I am happy to share our manuscript on a copper-dependent halogenase. Unbelievable effort by GS Yorick Chiang and Scientist @phdmasao at @uclachem @UclaCBE . Thank you to all collaborators and @NIGMS. nature.com/articles/s4158…
Thrilled to see our work on high-resolution #cryoem using a common LaB6 120-keV TEM and sub–200-keV direct electron detector, now online @ScienceAdvances. science.org/doi/10.1126/sc… . A collaboration with @GatanMicroscopy, @GeorgRamm, and @CryoEM_Monash.
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