Bioinformatics_News
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Ambitious bioinformatics analyst who can't wait to begin his career!
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Hidden deep inside the depth of internet, a treasure. #probability
Online now!✨RESEARCH: Bodogai et al identify a unique population of CD8+ T cells that accumulate during aging and actively promote tumor progression by suppressing antitumor CD4+ T cells nature.com/articles/s4358… rdcu.be/eH8JN
Understanding probability is essential in data science. In 4 minutes, I'll demolish your confusion. Let's go!
🎉Immune aging focus 🎉 Franceschi et al discuss tracking and intervening in inflammaging, through a personalized lens nature.com/articles/s4358… rdcu.be/eARAM
🎉 Big news! 🎉 Our AI platform, AgeXtend, just came out in #NatureAging. 🤖 Thanks @NatureAging, it was a great experience for us. Thanks @lab_sengupta @parul @tarini_ghosh @IIITDelhi @CompBio_IIITD @DBTIndia @serbonline @AnubhutiIhub @iiitdcai 🔗 nature.com/articles/s4358…
One of the reasons why it is so difficult to maintain weight loss is because adipose issue retains an epigenetic memory of obesity after weight loss. nature.com/articles/s4158…
Ilya Sutskever gave John Carmack a list of papers to read, so as to improve John's understanding of AI. That is a lot to read. If you want to quickly grasp what those papers are about, in this thread I share maps on over 20 of them 👇
Just dropped a 4 hour lecture on "Large Language Models": youtu.be/2yjzZfDQxy8 0:00 Basics of language models 2:30 Word2vec 16:27 Transfer Learning 19:23 BERT 1:00:39 T5 1:31:14 GPT1-3 1:53:05 ChatGPT 2:20:03 LLMs as Deep RL 2:53:00 Policy Gradient 3:32:50 Train your…
People always ask how the protein is expressed if I show the RNA data. Here are the 10 resources for protein data 👇 🧵
Today marks the 25th anniversary of Neil Risch and Kathleen Merikangas' classic 2-page paper that articulated GWAS as the future of human genetics. A short thread. www-leland.stanford.edu/~huatang/gene2…
Today in A.I: Sam Altman, the CEO of OpenAI and founder of ChatGPT is facing a senate hearing over the safety and regulation of A.I Here's the summary:
The strong inverse correlation between lifespan and mutation rate: we accrue mutations at a slower pace than many mammals but have roughly the same number of mutations by the end of our respective lifespans nature.com/articles/s4158… @Nature
Automate the tuning of hyperparameters with PyTorch Ignite using Bayesian Optimisation in Optuna. Learn more: medium.com/pytorch/using-…
List of publicly available bulk and sc COVID-19 RNA-seq datasets, with GEO+SRA links github.com/urmi-21/COVID-…
New preprint from my lab! We use CRISPR to test effects of genetic variants inside transcripts, validating a number of GTEx variants: eQTLs and rare variants triggering nonsense-mediated decay. We then test variants in two disease genes where NMD affects the phenotype.
A polyclonal allelic expression assay for detecting regulatory effects of transcript variants biorxiv.org/cgi/content/sh… #biorxiv_genetic
Our new preprint asks - "What happens when you give people identical bacterial sequence data and ask them to predict antimicrobial resistance?" Answer: A lot of disagreement biorxiv.org/content/10.110… 1/5
MapCaller - An integrated and efficient tool for short-read mapping and variant calling using high-throughput sequenced data biorxiv.org/content/10.110… github.com/hsinnan75/MapC…
Contaminant DNA in bacterial sequencing experiments is a major source of false genetic variability #bioRxiv biorxiv.org/content/10.110…
pysradb: A Python package to query next-generation sequencing metadata and data from NCBI Sequence Read Archive f1000research.com/articles/8-532… github.com/saketkc/pysradb
TPMCalculator: one-step software to quantify mRNA abundance of genomic features academic.oup.com/bioinformatics… github.com/ncbi/TPMCalcul…
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