CL_Li_Lab's profile picture. Associate Professor in St. Jude Children’s Research Hospital#interested in transcriptional regulation in cancer 3D genome@StJudeResearch

Chunliang Li

@CL_Li_Lab

Associate Professor in St. Jude Children’s Research Hospital#interested in transcriptional regulation in cancer 3D genome@StJudeResearch

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I am absolutely honored and humbled to officially receive the Research Scholar Grant from the American Cancer Society. So delighted to join the ACS family! Thank you #AmericanCancer #ACS_Research for recognizing and supporting our research. Thanks to my team and @StJudeResearch

CL_Li_Lab's tweet image. I am absolutely honored and humbled to officially receive the Research Scholar Grant from the American Cancer Society. So delighted to join the ACS family! Thank you #AmericanCancer #ACS_Research for recognizing and supporting our research. Thanks to my team and @StJudeResearch

So excited to receive the promotion notice to Associate Member on such a beautiful Monday morning! My department chair was Cc’ed and today is also his birthday. Also, 14 years ago today, I completed my Ph.D defense. Thank you for everyone I met during this journey.

CL_Li_Lab's tweet image. So excited to receive the promotion notice to Associate Member on such a beautiful Monday morning! My department chair was Cc’ed and today is also his birthday. Also, 14 years ago today, I completed my Ph.D defense. Thank you for everyone I met during this journey.
CL_Li_Lab's tweet image. So excited to receive the promotion notice to Associate Member on such a beautiful Monday morning! My department chair was Cc’ed and today is also his birthday. Also, 14 years ago today, I completed my Ph.D defense. Thank you for everyone I met during this journey.
CL_Li_Lab's tweet image. So excited to receive the promotion notice to Associate Member on such a beautiful Monday morning! My department chair was Cc’ed and today is also his birthday. Also, 14 years ago today, I completed my Ph.D defense. Thank you for everyone I met during this journey.

A big shoutout for Shaela, Jianzhong and Hong to lead this study. Thanks to all fantastic collaborators, especially our own @Junjyang for carrying out in vivo work. Cannot thank more for funding support. @ACS_Research @TheVFoundation @StJudeResearch

CRISPR screens helped St. Jude scientists learn more about certain cancers’ resistance to BET inhibitors and identify a combination approach to overcome that resistance in KMT2A rearranged leukemia. bit.ly/3zMLhzR @CL_Li_Lab @Junjyang @PNASNews

StJudeResearch's tweet image. CRISPR screens helped St. Jude scientists learn more about certain cancers’ resistance to BET inhibitors and identify a combination approach to overcome that resistance in KMT2A rearranged leukemia. bit.ly/3zMLhzR @CL_Li_Lab @Junjyang @PNASNews


Chunliang Li reposted

Inspired by nature, sourced from nature, designed for nature, and published in @Nature ! Biodegradable morphing robots are "gone to earth".


Chunliang Li reposted

Bottom Line: Sustained support from Congress allows @theNCI to raise paylines for R01 and ESI grants. As a result, in FY 2023, NCI expects to issue more than 100 additional R01 and ESI awards than last year. cancer.gov/grants-trainin…


Chunliang Li reposted

O’Neal Cancer Center Associate Scientist Rui Lu, Ph.D., has been named a 2023 James A. Pittman Jr., M.D., Scholar. The Pittman Scholars program recognizes the astounding research achievements and discoveries of junior faculty at @UABHeersink. 🔗: uab.edu/medicine/news/…

ONealCancerUAB's tweet image. O’Neal Cancer Center Associate Scientist Rui Lu, Ph.D., has been named a 2023 James A. Pittman Jr., M.D., Scholar. 

The Pittman Scholars program recognizes the astounding research achievements and discoveries of junior faculty at @UABHeersink.  

🔗: uab.edu/medicine/news/…

Check out our recent paper using advanced auxin inducible degron (AID2) and mutant reconstruction cellular system to study transcriptional impact of CTCF.

Scientists @stjuderesearch used a pioneering approach to degrade CTCF, a key protein in transcription biology, which helped them gain new insights into how the protein functions. @CL_Li_Lab @xubeisi @GenomeBiology bit.ly/3kAdZiW



Chunliang Li reposted

Malignant Progression of an Ancestral Bone Marrow Clone Harboring a CIC-NUTM2A Fusion in Isolated Myeloid Sarcoma aacrjournals.org/mcr/article-ab…


Chunliang Li reposted

Thrilled to share my primary PhD work: a Transcription Factor Atlas for understanding gene regulation and cell engineering @CellCellPress. We created a comprehensive TF ORF library and applied it to profile resulting expression changes. A thread 1/X sciencedirect.com/science/articl…


Chunliang Li reposted

“It is exciting & gratifying that investigations into hemoglobin & globin gene expression continue to produce new, clinically relevant discoveries,” Dr. Mitch Weiss says. Discover implications for sickle cell disease, published in @Nature. bit.ly/3yvdFpZ @ruopengfeng

StJudeResearch's tweet image. “It is exciting & gratifying that investigations into hemoglobin & globin gene expression continue to produce new, clinically relevant discoveries,” Dr. Mitch Weiss says. Discover implications for sickle cell disease, published in @Nature. bit.ly/3yvdFpZ @ruopengfeng

Chunliang Li reposted

Do you know an early-career scientist or trainee with an interest in childhood cancer survivorship research? Apply by Tuesday, November 1, for the Childhood Cancer Survivor Study Career Development Award. Learn more. bit.ly/3epILbs #CCAM #CancerResearch

StJudeResearch's tweet image. Do you know an early-career scientist or trainee with an interest in childhood cancer survivorship research? Apply by Tuesday, November 1, for the Childhood Cancer Survivor Study Career Development Award. Learn more. bit.ly/3epILbs #CCAM #CancerResearch

Chunliang Li reposted

We now welcome proteolysis-targeting antibodies (PROTABs) as degraders of cell surface receptors. @Nature nature.com/articles/s4158…


So true!

Scientists @stjuderesearch used a pioneering approach to degrade CTCF, a key protein in transcription biology, which helped them gain new insights into how the protein functions. @CL_Li_Lab @xubeisi @GenomeBiology bit.ly/3kAdZiW



Chunliang Li reposted

The most amazing science paper you can read this year! Synthetic embryos grown ex-utero (no sperm/no eggs/no utero needed) - the scientific basis for renewal.bio - the company me and @jacob_hanna just started! cell.com/cell/fulltext/…


Chunliang Li reposted

Findings from St. Jude scientists have revealed a new therapeutic target for an aggressive type of rhabdomyosarcoma. ow.ly/LTXo50JVYpp @ScienceTM #childhoodcancer

StJudeResearch's tweet image. Findings from St. Jude scientists have revealed a new therapeutic target for an aggressive type of rhabdomyosarcoma. ow.ly/LTXo50JVYpp
@ScienceTM #childhoodcancer

Chunliang Li reposted

Following a promising first year of our 2022–27 strategic plan, we’re increasing our investment in programs to advance the study and treatment of pediatric cancer and other catastrophic diseases. Learn more. ow.ly/f1sU50JUXAR #StJudeResearch

StJudeResearch's tweet image. Following a promising first year of our 2022–27 strategic plan, we’re increasing our investment in programs to advance the study and treatment of pediatric cancer and other catastrophic diseases. Learn more. ow.ly/f1sU50JUXAR #StJudeResearch

Chunliang Li reposted

Fun fact! The name Ki67 derived from the city of Kiel (Ki) where the antibody was produced in the university department of pathology and refers to the number of the original clone (67). #Ki67


So exited to meet with other V-scholars and discuss cool science we are doing!@TheVFoundation

CL_Li_Lab's tweet image. So exited to meet with other V-scholars and discuss cool science we are doing!@TheVFoundation

“it is difficult to predict where breakthroughs in medicine will come from, but one certainty is investments in education, training, and basic-science–driven discovery often reap dividends far beyond original cost, enabling chance to favor prepared mind” journals.plos.org/plospathogens/…


Chunliang Li reposted

We're speeding up cancer discoveries & reducing barriers with $50M in grants to @DanaFarber @HopkinsKimmel, @MSKCancerCenter, @kochinstitute, & @MDAndersonNews to find cures for some of the deadliest cancers. Learn more: bit.ly/3vPtU0G #breakthroughcancer


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