Alan Lewis
@ERCstemcells
CEO of Stem Cell Company Medistem (MEDS), Previous CEO of Juvenile Diabetes Research Foundation. I am Committed to Treating Type 1 Diabetes and Complications.
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we published a peer-reviewed paper on our Endometrial Regenerative Cell (ERC) stem cell trial for heart failure translational-medicine.com/content/pdf/14…
topical application of mesenchymal stem cells for treatment of diabetic ulcers ncbi.nlm.nih.gov/pubmed/23423568
TNF-alpha an important mediator of diabetic complications ncbi.nlm.nih.gov/pubmed/23484152 ERC inhibit TNF-alpha
tolerogenic vaccine using insulin and igf-1 for type 1 diabetes
nasal insulin induces tolerogenic signals in adult diabetics ncbi.nlm.nih.gov/pubmed/21307076
Anakinra reduces insulin requirements in small study on type 1 diabetics ncbi.nlm.nih.gov/pubmed/21518168
clinical trial using abatacept (CTLA4-Ig) in type 1 diabetes, some improvement ncbi.nlm.nih.gov/pubmed/21719096
vitamin d3 increases t regulatory cell numbers ncbi.nlm.nih.gov/pubmed/22069289 but does not increase insulin in healthy volunteers
immunization with GAD65 does not have clinical benefits in type 1 diabetes, results of a trial ncbi.nlm.nih.gov/pubmed/22296077
foxp3 increases after administering anti-CD25 antibodies as part of islet transplantation ncbi.nlm.nih.gov/pubmed/22364726
clinical trial of rapamycin and il-2 to increase Treg in type 1 diabetes, increases treg, but messes up islet ncbi.nlm.nih.gov/pubmed/22721971
excellent paper showing adjuvant effect of B cell depletion on preventing #diabetes through tolerance induction ncbi.nlm.nih.gov/pubmed/23405091
mesenchymal #stem_cells home to pancreas and also stimulate PDX-1 expression in islets ! ncbi.nlm.nih.gov/pubmed/19062254 excellent paper
diabetes is caused by deficient SDF-1 mediated recruitment of Treg to pancreas ?? ncbi.nlm.nih.gov/pubmed/23042535 Juventas you have new target !
Type 1 diabetes cured in dogs for the first time, paving the way for humans fb.me/HGEEfQvC
interesting paper saying that resveratrol may be useful for preventing diabetic complications of pregnancy ncbi.nlm.nih.gov/pubmed/23436883
inhibiting NF-kappa B protects transplanted islets from rejection ncbi.nlm.nih.gov/pubmed/23437272
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