Elliott Lab
@Elliott_Lab_Ox
Latest news from the lab of Paul Elliott. Ubiquitin | Structural biology | Biochemistry. Views our own.
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Really honoured to have received this funding from CRUK to support the Lab – it enables us to venture into new and exciting directions investigating how highly aneuploid cancer cells exploit certain ubiquitin ligases for their survival.
[1/3] Meet the latest #CRUKFunded researchers awarded Programme Foundation Awards by our #DiscoveryResearch Committee. Read about their programmes below & learn more about our scheme here: bit.ly/4bDg2b7
We are hiring! Two structural biology/biochemistry postdoc positions are available in our lab - come and join a lively Team in the thriving city of Oxford! Deadline 4th October 2024. Further details are here: my.corehr.com/pls/uoxrecruit…
Having a great time talking science in the sun ☀️
✨What a group!✨Some fantastic research shared so far and there’s still much more to come. We’re looking forward to some down time in the Portuguese sunshine to rest and reset for this afternoons session #Ubiq24
We’re hearing about UBIQUITIN SIGNALLING IN CELL SURVIVAL AND CELL DEATH from @Elliott_Lab_Ox #Ubiq24
#TECPR1 replaces #ATG16 as receptor of the ATG5/ATG12 E3 ligase to conjugate #LC3 to damaged vesicles displaying sphingomyelin on their cytosolic face. New LC3 ligase for #autophagy and first ever receptor for sphingomyelin! Discovered by K.Boyle... embopress.org/doi/full/10.15…
We are excited to announce @Biochem_Journal, @StablixInc, @ubiquigent, @BiosynthGroup, @entactbio and @UbiQbio are all sponsors of our DUBS 2023 scientific meeting. Learn about the variety of sponsorship packages available here: ow.ly/jbz350ONUo1
It's been great to have you join us for these last few weeks, Yanis, and glad you saw Oxford in so much sunshine ☀️
Thanks @Elliott_Lab_Ox for hosting @mace_yanis from @LabSoap @nbidere - grateful to @ProteoCure @NantesUniv #DoctoralSchool @laliguecancer
Congratulations to the new Dr Schönewolff @EguesMaribel - first DPhil of the Lab! Thanks to examiners Yogesh & John for great scientific discussions! @YKulathu @ERADLab
Great Department Away Day @BiochemOxford last week full of interesting talks rounded off brilliantly by @larissadi2
A great PhD opportunity in structural biology!
We have a place available on our Wellcome Cellular Structural Biology program for 2023 entry and are accepting applications. It is a fantastic program. Encourage your students to apply!
Excited to share our most recent work on the giant ubiquitin ligase #BIRC6 out now in @ScienceMagazine science.org/doi/10.1126/sc…! Thread below 🧵 (1/7)
Congratulations also to @fisherlab1 (@moritzhunkeler) and @clausen_lab (@julianehrmann) for great BIRC6 publications too! science.org/doi/10.1126/sc… science.org/doi/10.1126/sc…
Amazing work from our colleagues @Elliott_Lab_Ox in Science today. Congratulations, what a monster of a structure and lovely biochemistry as well! science.org/doi/10.1126/sc…
Delighted to share our latest structural & biochemical work uncovering how the gigantic #ubiquitin ligase, BIRC6, regulates cell death - out now in @ScienceMagazine! science.org/doi/10.1126/sc… @BiochemOxford @larissadi2 @CaraEllison8 @adanpinto @BenedicktKessler
Great to show you around the @BiochemOxford Ivan and to chat about ubiquitin on a sunny day in Oxford!
Five miles #walkingmeeting with Paul Elliot from @BiochemOxford talking about structures of BIRC6 ubiquitin ligase complex that ubiquitinates #Caspases and is supressed by SMAC. 😊 @UniofOxford @Dunn_School @IBC2_GU @RMU_EMTHERA biorxiv.org/content/10.110…
Thanks for attending the very first Ubiquitomics Conference @UniofOxford! The presentations were excellent and generated very exciting discussions. A big shout out to all @KebleOxford for having us. Until the next one!
So excited to share latest work from @Elliott_Lab_Ox! We find BIRC6, an enormous #ubiquitin IAP ligase, directly inhibits caspases and we show how this is blocked by SMAC. biorxiv.org/content/10.110… Plus great mass spec collab with @adanpinto @kesslerlabox
What a week for BIRC6! Great complementary work by @clausen_lab biorxiv.org/content/10.110… and @fischerlab1 biorxiv.org/content/10.110… Happy reading everyone!
Delighted to share our latest work where we reveal how a gigantic ubiquitin ligase prevents cell death and is itself inhibited biorxiv.org/content/10.110…
And here's Day 2. Spread the word! Register here today: oxforduniversitystores.co.uk/conferences-an…
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