Greg Duncan
@GregDuncs
Assistant professor @ UMN. My lab studies how myelin regulates the function and health of neurons. Father and husband who loves the outdoors.
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nature.com/articles/s4146… I am excited to announce our work on how myelin loss culminates in neurodegeneration has been published at Nature Communications. While I have previously covered our findings as a preprint in more detail below, our key findings are:
New work from Yasmine Kamen shows that differentiating oligodendrocytes are filled with the zymogen procaspase-3. This provides a specific marker for new oligodendrocytes and suggests a role for this pathway in oligodendrocyte fate decisions. biorxiv.org/content/10.110…
And the completion of this story was only possible because of all the help from the most amazing @Anya_A_Kim and Björn Neumann in the Franklin lab!🥰
Why is age the main risk for Alzheimer’s disease? Mouse models reveal that the loss of myelin integrity is causally linked to enhanced plaque deposition. Great work by @ConstanzeDepp, @TingSun_MPINAT et al. in Nature nature.com/articles/s4158…
Excited to see our preview of the great work from Su et al. published in Neuron on how astrocyte endfeet regulate myelination. Their work gives an excellent insight into how astroycte-oligo interactions shape myelination. cell.com/neuron/fulltex… cell.com/neuron/fulltex…
A great opportunity 👇
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