Sanchez-Gurmaches Lab
@JSG_Lab
Assistant Professor at CCHMC. #obesity #metabolism #brownfat #adipocyte. Tweets and opinions are those of JSG and do not reflect my employer's.
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Excited to share our recent work on organoid vascularization, now out in @CellCellPress! Grateful to all our amazing collaborators who made this possible! @CuSTOM_CCHMC @UCLAstemcell
Congrats @MingxiaGu and all the teams collaborating on this latest advance in stem cell and lung organoid research, just out @CellCellPress! "Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut organoids" cell.com/cell/fulltext/…
cell.com
Co-development of mesoderm and endoderm enables organotypic vascularization in lung and gut...
Recapitulating the concurrent development of germ layers through the co-differentiation of mesoderm and endoderm within a single spheroid enabled the generation of vascularized lung and intestinal...
Excited to share our new publication in @MolMetab on sex-specific actions on human adipose tissue through Sex Hormone Binding Globulin (SHBG)! Our study provides new insights into how SHBG regulates lipolytic pathways through adipocyte internalization. sciencedirect.com/science/articl…
A nitroalkene derivative of salicylate, SANA, induces creatine-dependent thermogenesis and promotes weight loss go.nature.com/3SZcRDD
Congratulations to Zoltan Arany appointed Chair of the Department of Physiology, Perelman School of Medicine!
🌟Call for Papers🌟 📚 #Metabolic and #Lipidomic Reprogramming in #Cancer: Mechanisms and Therapeutic Potential 👨🔬Guest Editors: Dr. Sara Vicente-Muñoz, and Dr. Mariaelena Pistoni 🔗More Info: mdpi.com/journal/metabo… ⏰Submission Deadline: 31 December 2025
Great lecture today by Dr. Francesc Villarroya at the @EASOobesity congress. Glad to had the opportunity of listening for the first time about brown adipose tissue repressors.
💠Bona diada de Sant Jordi!💠 Dpt Bioquímica i Biomedicina Molecular UB 🌹🐉📚 ub.edu/portal/web/dp-… @BQBiomedMolUB @BiologiaUB @IBUB_UB
♂ Dia Internacional de les Dones 📢 Des de @recercauniscat ens afegim a les reivindicacions #8M🚺 a través de l’Estratègia d’igualtat de gènere en la ciència (EIGEC) que preveu #LaLleidelaCiència, elaborada en col·laboració amb @igualtatcat 🔗gen.cat/43rnghW #8M2025
I don’t often comment on policy, but this moment is too important. Like many labs across the U.S., mine has trained undergrads, grad students & postdocs who now advance human health & our understanding of the natural world. (📸: My lab over the years.)
1/ New paper alert! Excited to share our latest work on hepatic mitochondrial subpopulations and their distinct roles in MASH progression! 👉 Read here: nature.com/articles/s4200… #LiverResearch #Mitochondria #Metabolism #MASH #MASLD
nature.com
Functional compartmentalization of hepatic mitochondrial subpopulations during MASH progression
Communications Biology - Isolation and characterisation of hepatic cytoplasmic (CM) and peridroplet mitochondria (PDM) from simple steatosis to advanced MASH. PDM showed higher pyruvate oxidation...
#11F, International Day of Women and Girls in Science, we want to highlight the scientific talent of the women who drive research forward at #IBUB. We are not all of them, but they represent all of us. 💜🔬 #11FdonesIBUB #11FdoneSTEMUB
🚨We are hiring!🚨 We have postdoctoral positions available! If you're passionate about studying cardiac regeneration and development, join our team in vibrant and beautiful Montreal! Please help spread the word 🫶 For more details see here research.chusj.org/RECHERCHE/fi...
Congrats @ManasiHalurkar !! @CincyResearch @CincyChildrens @NatureComms
I am delighted to share that our paper about the widely used UCP1-CreEvdr transgene is out in Nature communications!🎉 I am thankful to @JSG_Lab for pushing through to make an impact to the field. This wouldn’t be possible without all the co-authors, I am very thankful to all!😄
Today, we report that chronic intermittent fasting impairs beta-cell maturation & function in adolescent mice. Using scRNAseq, we delineated a maturation score for beta-cells. Long-term good if you're older, might be harmful if you are still developing! 👇 cell.com/cell-reports/f…
The widely used Ucp1-Cre transgene elicits complex developmental and metabolic phenotypes @NatureComms nature.com/articles/s4146…
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