Luker Lab
@LabLuker
Molecular imaging lab at the University of Michigan studying breast cancer, metastases, and myelofibrosis
In our latest issue @luker_md, @LabLuker & co-workers from @UMichRadiology use a physiologically-relevant model of bone marrow disseminated tumor cells to tackle one of the biggest problems in clinical #BreastCancer: delayed recurrence. nature.com/articles/s4138…
Looking for a postdoctoral position? The Luker lab is hiring! jobs.sciencecareers.org/job/504972/pos…
jobs.sciencecareers.org
Postdoctoral Research Fellow - Ann Arbor, Michigan
Post-doc with expertise in multi-scale, quantitative imaging and cell biology to investigate metastasis-initiating cells in breast cancer.
We have a new #OpenAccess review @Cancers_MDPI, "Metabolic Regulation of Redox Balance in Cancer", led by @VineePurohit w/ @MadameSurgeon. We detail how cancer cells upregulate mechanisms that make & quench ROS and vulnerabilities. Plus: pretty figures!😀 mdpi.com/2072-6694/11/7…
The Luker lab is excited to congratulate Dr. Phil Spinosa, our collaborator who successfully defended yesterday. Phil’s PhD is in Chemical Engineering and his primary advisor is Dr. Jennifer Linderman. @UMichRadiology @UMichMedicine @UMengineering .
Maintaining mental health is a challenge in research but we can all help create a healthy research environment! @UMRogelCancer @UMichRadiology @UMichMedicine @UMengineering sciencemag.org/careers/2019/0…
A new study of single-cell #CXCR4 signaling dynamics suggests kinase inhibitors may inadvertently activate #metastatic pathways downstream of CXCR4. @UMich stke.sciencemag.org/content/12/589…
New multidisciplinary work from @LabLuker in @scisignal "establishes how changing environmental inputs modulate CXCR4 signaling in single cells and provides a framework to optimize the development and use of drugs targeting this signaling pathway." stke.sciencemag.org/content/12/589…
Read our most recent publication: Short-term cellular memory tunes the signaling responses of the chemokine receptor CXCR4 stke.sciencemag.org/content/12/589…
As if we needed another reason to love our #pets...🐶🐱 New @UMich research led by @umichsph's @mjanevic found that pets have the potential to help older adults cope and function better with #chronicpain, as well as improve sleep, mood, and more. READ: myumi.ch/LEly5
In a collaboration between @UMRogelCancer and @UMengineering, researchers built a device they believe could help predict the likelihood #BreastCancer will metastasize. #BCSM Read more: michmed.org/e9Ym6
Check out this version of one of the most famous classes on #happiness: myumi.ch/a83XM via @TheAtlantic #WeekendRead
Check out our latest work!
Elevated PAI1 (SERPINE1) drives glycolytic metabolism, actin rearrangement, and increased invasiveness in TNBC models. bit.ly/2Jc4J0C
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