Alexander Ploss
@PlossLab
Infectious disease biologist, innovator, entrepreneur
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Great #TWiV episode with @profvrr and @RichCondit interviewing our very own @maini_lab and John Tavis at the International #HBV meeting in Chicago! @PlossLab @ICE_HBV @HepBFoundation @GlobalHep
Thank you very much @MoAlQuraishi for an outstanding keynote lecture and great discussions at the International #HBV meeting in #Chicago. @HepBFoundation @iannaconelab
Please check out our newest study led by our very own @KeithBerggren biorxiv.org/content/10.110… Many thanks to our brilliant collaborators at @RobSchwartzLab @Crittermechanic @KleinerLabRNA @PrincetonMolBio @NCStateVetMed @Princeton #liver #HBV #epitranscriptome #RNA
Just a quick reminder that the abstract submission deadline for the international #HBV meeting hbvmeeting.org is June 28 (3pm EDT)! Please register and submit your abstracts! @iannaconelab @HepBFoundation and I are looking forward to welcoming you in #Chicago Please RT
Loke and colleagues quantify the relative and interactive contributions of genetic and environmental influences on heterogeneity in immune profiles and helminth susceptibility. Read it here: rdcu.be/dKPrZ nature.com/articles/s4159…
Deadline E X T E N D E D! Applications📄 are now⏳ being accepted for the 2024 MolBio Scholars program. For more info and to apply, visit: molbio.princeton.edu/graduate/molbi…
🆕Hepatology Snapshot❕ Formation and transcriptional regulation of hepatitis B virus covalently closed circular DNA Full text here👉journal-of-hepatology.eu/article/S0168-… @plosslab #LiverTwitter
Babies born to a mother with #hepatitisB have a greater than 90% 📈 chance of developing hepatitis B if they're not properly treated at birth. 👩🏽🍼 🔊If your doctor is aware that you have #hep B, they can prevent transmission to your baby. Learn more 💻 hepb.org/treatment-and-…
Adults in the U.S. have very low rates of vaccination, primarily because many were born before the vaccine became a health care standard & mandated for school. 💉The #hepB vaccine is widely used with 1 billion + doses given & is one of the safest & effective vaccines in the 🌍
Applications📄 are now⏳ being accepted for the 2024 MolBio Scholars program. For more info and to apply, visit: molbio.princeton.edu/graduate/molbi…
CRISPR is an amazing gene🧬-editing tool! And the @bsadamson Adamson lab is making it even better!! Read the explainer/press release about their major improvement to prime editing, published in Nature: molbio.princeton.edu/news/2024/adam…
It has been an immense privilege and honor to review with John MacMicking and Carl Nathan in @ScienceMagazine the past 40 years of IFN-gamma research, and reflect on its neglected and potential role as a medicine science.org/doi/epdf/10.11…
Please check out our newest study deciphering diff. in signaling strength betw type I&III #interferon receptors science.org/doi/10.1126/sc… Outstanding work by @EmilyMesev + fantastic collaboration with the terrific @toettch ! Thanks to everyone involved! @PrincetonMolBio @Princeton
Thank you very much @RMedzhitov for an excellent, thought provoking seminar and insightful discussions during your visit @Princeton EEB and @PrincetonMolBio #immunology @CJEMetcalf @Grahammunology
Fantastic collaboration with @cambearon on the development of qCARMEN! Outstanding work by lead author @realbriankang aided by Jiayu Zhang, Michael Schwoerer, Amy Nelson and many others. @PrincetonMolBio @Princeton @PrincetonCHW
Really excited to share the first preprint from a project that started in my lab! We hope that others find this approach for scalable, multiplexed, CRISPR-based quantification of gene expression useful. See the thread from first author @realbriankang summarizing qCARMEN:
World #HepatitisDay23 ! Get vaccinated, get tested, get treated. #eliminate #hepatitis #liver @NO_hep @PrincetonMolBio @EASLEUAffairs @AASLDtweets @HepBFoundation @Princeton
Our new work in @Nature to explain how retrotransposons synthesize the 2nd-strand DNA by a circularization process. Story: made some cool findings (we thought) -> actually scooped 40-yr ago by textbook knowledge -> textbook appear to be incorrect. nature.com/articles/s4158…
Our newest study is now online! #Hepatitis delta virus #HDV RNA decline post-inoculation in human NTCP transgenic mice is biphasic | mBio journals.asm.org/doi/10.1128/mb… Congratulations to @stephmaya8 Leeor & Fabian and everyone else involved! @PrincetonMolBio @LoyolaChicago @NO_hep
RNA is informant and agent. Controlled RNA export from cells could enable cell-cell delivery of functional and non-destructive tracking of cell dynamics. Our new paper, led by brilliant @FelixHorns, engineers RNA export for both capabilities: authors.elsevier.com/sd/article/S00…
Excited to share our labs first @Nature paper! In collaboration with @VintherLab we show that hepatitis C virus #RNA is capped with FAD protecting it from innate immune sensing. rdcu.be/df8p5 Congrats Anna Sherwood and Lizandro Rivera-Rangel 👏🏻🍾 #HCV @UCPH_health
Nature research paper: Hepatitis C virus RNA is 5′-capped with flavin adenine dinucleotide go.nature.com/44nyQYy
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