Patricia Marqués González
@Pmarques_G
Postdoctoral researcher at Karolinska Institutet. Aging, metabolism, immunology and more 🧬✨
In Vivo Chemical Reprogramming Is Associated With a Toxic Accumulation of Lipid Droplets Hindering Rejuvenation onlinelibrary.wiley.com/doi/full/10.11…
A Cellular and Transcriptomic Atlas of the Aged Mouse Hematopoietic System onlinelibrary.wiley.com/doi/full/10.11…
Wow, mind-blowing study showing that immune T cells release “telomere Rivers” into circulation after acquiring them from other cells. In aged mice, telomere Rivers extended lifespan by 17 months (though n = 10), with some mice living nearly 5 years 🤯
CD4⁺ T cells confer transplantable rejuvenation via Rivers of telomeres biorxiv.org/content/10.110…
The Normal Aging Lung Single Cell Atlas is finally out!!! Lung aging is cell-type dyssynchronous, with alveolar epithelial & endothelial cells showing ⬆️ changes in gene expression, somatic mutations burden, transcriptional entropy. 👏🏼 @ruben_deman 👏🏼 nature.com/articles/s4146…...
Terrible noticia. La falta de confianza en las vacunas acarrea graves consecuencias. Esta es una de ellas.
🔴ÚLTIMA HORA | La OMS retira a España el estatus de país libre de sarampión social.elpais.com/pdami1
🎙️ We’re excited to kick off 2026 with our first @YicsaC webinar featuring @OElsallabi (@univUda Italy 🇮🇹). 🧬 Senescence, ovarian aging & senotherapeutics 👉 Register: us06web.zoom.us/meeting/regist… #yICSAWebinarSeries #Senescence #AgingResearch #ECRs #PostdocLife
One of my former research assistants was killed by ICE in Minneapolis today😢 Alex was the kindest, sweetest human and a ICU nurse with a bright future ahead of him May his soul rest in peace and this senseless carnage stop💔
Aroca-Crevillén, @AndrsHidalgo16 et al identify a circadian checkpoint in #neutrophils, mediated by the CXCL12–CXCR4 axis, that limits tissue injury by inhibiting their intrinsic circadian clock hubs.la/Q03_6K9C0 📘 #Immunology Update Winter 2026 👉hubs.la/Q03_6Jb90
New research shows how exercise protects aging muscle by rebalancing mTORC1. In young muscle, mTORC1 is carefully regulated, allowing protein building while still clearing out damaged components. With aging, this balance breaks down. A transcription factor called DEAF1 becomes…
Senotherapeutics for Brain Aging Management mdpi.com/2035-8377/17/1…
Senescent Cell Clearance Ameliorates Temporal Lobe Epilepsy and Associated Spatial Memory Deficits in Mice onlinelibrary.wiley.com/doi/10.1002/an…
Rejuvenation of white adipose tissue in a longitudinal heterochronic transplantation model biorxiv.org/content/10.648…
DNA-damaging chemotherapy reshapes cardiac-resident macrophage composition and function | Science Immunology science.org/doi/10.1126/sc…
Academia isn't a calling—it's a job. Stop glorifying burnout. Clock in, do great work, clock out. Your worth isn't measured in unpaid overtime
Senescent CD8+ T Effector Memory Cells are Functionally Impaired, Enriched in Aging and Disease, and a Barrier to Immunotherapy biorxiv.org/content/10.648…
Mitochondria migrate toward the cell membrane in response to high glucose levels, and this movement may play a role in regulating #insulin release. spkl.io/6014Air4w Shankar Mukherji & colleagues @BiophysJ
Mitochondrial RNA cytosolic leakage drives the SASP | Nature Communications nature.com/articles/s4146…
Mitochondrial dysfunction in cellular senescence: a bridge to neurodegenerative disease nature.com/articles/s4151…
Check out our latest paper on in vivo engineering of human HSPCs using lentiviral vectors and virus-like particles! @NatureBiotech
In vivo gene editing of human hematopoietic stem and progenitor cells using envelope-engineered virus-like particles go.nature.com/4a39S6X
🚨 NEW: One of the largest COVID-19 vaccine studies ever (28 MILLION people in France) just dropped. Results? • 74% lower risk of death from severe COVID-19 • 25% lower risk of all-cause mortality • No increase in 4-year mortality • Vaccinated people had lower risk of death…
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