gcchen12's profile picture. Chen lab @AcadSinica working on Autophahy and PTP signaling in development and diseases

Guang-Chao Chen

@gcchen12

Chen lab @AcadSinica working on Autophahy and PTP signaling in development and diseases

Guang-Chao Chen reposted

📣 UPDATE 11th International Symposium on Autophagy Missed the abstract submissions? Good news! Late poster abstract submissions are still open. Act fast, submissions close 10th October. Register here: isa11.org/registration

LazarouLab's tweet image. 📣 UPDATE 11th International Symposium on Autophagy 

Missed the abstract submissions?

Good news! Late poster abstract submissions are still open. Act fast, submissions close 10th October. 
Register here: isa11.org/registration

Guang-Chao Chen reposted

📣The #EDRC2025 will select proposals for six workshops, each with up to nine speakers (12 minutes presentations + 3 minutes Q/A). If you are interested in hosting a workshop, please send a one-page proposal to [email protected] by May 5, 2025 🧪🪰

edrc2025's tweet image. 📣The #EDRC2025 will select proposals for six workshops, each with up to nine speakers (12 minutes presentations + 3 minutes Q/A). If you are interested in hosting a workshop, please send a one-page proposal to edrc2025alicante@umh.es by May 5, 2025 🧪🪰

Guang-Chao Chen reposted

12 lessons students learn in the Sinclair Lab: Lesson 1. Write the way you speak

davidasinclair's tweet image. 12 lessons students learn in the Sinclair Lab:
 
Lesson 1. Write the way you speak

Guang-Chao Chen reposted

Lactate controls cancer stemness and plasticity through epigenetic regulation dlvr.it/TJwtQM

Cell_Metabolism's tweet image. Lactate controls cancer stemness and plasticity through epigenetic regulation dlvr.it/TJwtQM

Guang-Chao Chen reposted

MIF-ACKR3 causes irreversible fat loss by impairing adipogenesis in cancer cachexia dlvr.it/TJz6FK

Cell_Metabolism's tweet image. MIF-ACKR3 causes irreversible fat loss by impairing adipogenesis in cancer cachexia dlvr.it/TJz6FK

Guang-Chao Chen reposted

In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion. Learn more: scim.ag/4iT8mpD

ScienceMagazine's tweet image. In a new Science study, cryo–electron tomography captures the in-cell architecture of the mitochondrial respiratory chain, illuminating how the coordinated action of molecular machines drives life’s fundamental energy conversion.

Learn more: scim.ag/4iT8mpD

Guang-Chao Chen reposted

The deubiquitinase USP45 inhibits #autophagy through #actin regulation by Coronin 1B, say Yuchieh Jay Lin, Guang-Chao Chen, and colleagues @IBCSinica hubs.la/Q03bjMLh0

JCellBiol's tweet image. The deubiquitinase USP45 inhibits #autophagy through #actin regulation by Coronin 1B, say Yuchieh Jay Lin, Guang-Chao Chen, and colleagues @IBCSinica hubs.la/Q03bjMLh0

Guang-Chao Chen reposted

🚨 Call for Submissions! 🚨 We're thrilled to announce the opening of the Beth Levine PhD Prize! 🎓🏆 If you’ve completed an outstanding thesis in #Autophagy, this is your chance to get recognized. 📅 Deadline: May 19th, 2025 🔗 Apply now: cfatg.org/bourses/prix-d…

CFATG's tweet image. 🚨 Call for Submissions! 🚨
We're thrilled to announce the opening of the Beth Levine PhD Prize! 🎓🏆 If you’ve completed an outstanding thesis in #Autophagy, this is your chance to get recognized.
📅 Deadline: May 19th, 2025
🔗 Apply now: cfatg.org/bourses/prix-d…

Guang-Chao Chen reposted

Lysosomal acidification is key for cellular health, w/ impairment linked to aging & neurodegenerative disease. Lin et al identify USP45 as a negative regulator of #autophagy, inhibiting V-ATPase localization to autolysosomes via Coronin 1B-actin modulation hubs.la/Q03bjMk-0

JCellBiol's tweet image. Lysosomal acidification is key for cellular health, w/ impairment linked to aging & neurodegenerative disease. Lin et al identify USP45 as a negative regulator of #autophagy, inhibiting V-ATPase localization to autolysosomes via Coronin 1B-actin modulation hubs.la/Q03bjMk-0

Our new paper showing USP45 antagonizes autolysosomal function! rupress.org/jcb/article/22…


Guang-Chao Chen reposted

ATG9A is a weaving loom of #autophagy. doi.org/10.1083/jcb.20… Go ahead, satisfy your curiosity: Not only does #ATG9A contribute to phagophore formation but it works hard until the very end to close nascent phagophores and form the double membrane #autophagosome.

vpderetic's tweet image. ATG9A is a weaving loom of #autophagy. doi.org/10.1083/jcb.20…

Go ahead, satisfy your curiosity: Not only does #ATG9A contribute to phagophore formation but it works hard until the very end to close nascent phagophores and form the double membrane #autophagosome.
vpderetic's tweet image. ATG9A is a weaving loom of #autophagy. doi.org/10.1083/jcb.20…

Go ahead, satisfy your curiosity: Not only does #ATG9A contribute to phagophore formation but it works hard until the very end to close nascent phagophores and form the double membrane #autophagosome.

Guang-Chao Chen reposted

OptoTrap for endogenous protein clustering in Drosophila. COOL!! In vivo optogenetic manipulations of endogenous proteins reveal spatiotemporal roles of microtubule and kinesin in dendrite patterning | Science Advances science.org/doi/10.1126/sc…


Guang-Chao Chen reposted

Emerging roles of #ubiquitin in regulating dynamic changes of membrane protein complexes have diverse biological functions including #organelle structures, selective #autophagy and others...Thx Anne @acjacomin for your fantastic contribution😊😀


Guang-Chao Chen reposted

Our new paper proposing a method to simultaneously measure multiple organelles is out in @PLOSBiology! We aimed to explore landscapes of cells or organelles by combining multidimensional data obtained from fluorescence spectral imaging. Thanks to everyone at @MizLabUT !

How can we track the heterogeneity & dynamics of #organelles? @MizLabUT &co present a multi-parametric, fluorescence #spectroscopy method that allows simultaneous visualization of a wide array of organelles in different maturation states #PLOSBiology plos.io/4gFeJfs

PLOSBiology's tweet image. How can we track the heterogeneity & dynamics of #organelles? @MizLabUT &co present a multi-parametric, fluorescence #spectroscopy method that allows simultaneous visualization of a wide array of organelles in different maturation states #PLOSBiology plos.io/4gFeJfs


Guang-Chao Chen reposted

#RegistrationAlert The next @CFATG annual symposium in south of #France will have amazing keynote speakers, including @vpderetic, @EileenWhitePhD and @Lab_Vassiliki. Do not miss it! All info: atoutcom.com/autophagy/

CFATG's tweet image. #RegistrationAlert The next @CFATG annual symposium in south of #France will have amazing keynote speakers, including @vpderetic, @EileenWhitePhD and @Lab_Vassiliki. Do not miss it! All info: atoutcom.com/autophagy/

Loading...

Something went wrong.


Something went wrong.