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Jake Batchelder

@jakebatch11

Jake Batchelder reposted

I am thrilled to announce I'll be joining @StJude Children's Research Hospital as a Postdoctoral Research Fellow at @TheBlanchardLab. Looking forward to being part of an exceptionally talented research group and immerse myself in working with #smFRET and #CryoEM methods #postdoc


Jake Batchelder reposted

Here is a nice post in @NaturePortfolio summarizing our recent findings on the chemotherapeutic CX-5461, written with @MinPAN47830227, @jakebatch11 and @TheBlanchardLab. cancercommunity.nature.com/posts/the-chem…


Jake Batchelder reposted

New paper out from our lab investigating the use of the putative RNA-POL I inhibitor CX-5461 in pediatric neuroblastoma. I believe this study represents a fantastic example of why the details of drug mechanism are deeply important for patient safety. nature.com/articles/s4146…

nature.com

The chemotherapeutic CX-5461 primarily targets TOP2B and exhibits selective activity in high-risk...

Nature Communications - CX-5461 recently progressed through phase I clinical trial as a first-inhuman inhibitor of RNA-POL I. Here, the authors demonstrate that CX-5461 synergizes with...


Jake Batchelder reposted

Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores pnas.org/content/early/…

TheBlanchardLab's tweet image. Tuning the Baird aromatic triplet-state energy of cyclooctatetraene to maximize the self-healing mechanism in organic fluorophores pnas.org/content/early/…

Jake Batchelder reposted

So proud to be a part of this outstanding collaborative effort to explore the unexpected discovery and physiological significance of an EMT-associated ribosome biogenesis program: disq.us/t/3ehf3jj


Jake Batchelder reposted

Our previous paper showed that variant rRNA alleles are conserved and exhibit tissue-specific expression (Parks et al. Sci Adv). We now show that a conserved rRNA allele in E. coli is upregulated under stress and can regulate gene expression and phenotype. cell.com/cell-reports/f…


Jake Batchelder reposted

In a new @ScienceAdvances study, @TheBlanchardLab and team found that each person contains a wide variety of #ribosomes. Study suggests that genetic variation of rDNA may affect the way proteins are built, linking to developmental disorders. bit.ly/2oJo51k

WeillCornell's tweet image. In a new @ScienceAdvances study, @TheBlanchardLab and team found that each person contains a wide variety of #ribosomes. Study suggests that genetic variation of rDNA may affect the way proteins are built, linking to developmental disorders. bit.ly/2oJo51k

Jake Batchelder reposted

A paper just published in Science Advances, "Variant ribosomal RNA alleles are conserved and exhibit tissue-specific expression," reveals that the sequences of ribosomal RNA within the mammalian ribosome may be significantly more divergent than expected: advances.sciencemag.org/content/4/2/ea…


Jake Batchelder reposted

Grad school can be rough! #Doctors #research #sciencefunny

SantaCruzBio's tweet image. Grad school can be rough!

#Doctors #research #sciencefunny

Jake Batchelder reposted

Crick and Reynolds is the take for pirates in mccutchen deal. @extrabaggs @PavlovicNBCS on it. i only wish tony watson was still with the pirates so he could have combined to form a crick and watson combo in their pen (nerd joke)


@dodgerhat this is a great tweet. Why didn’t you like it???


Jake Batchelder reposted

When you start a business but you have a life also

MensHumor's tweet image. When you start a business but you have a life also

Jake Batchelder reposted

Madison Bumgarner's first pitch is a called strike, and all is right with the world. OK. Maybe not.


Jake Batchelder reposted

Mets fans waking up, finding out they've signed Tim Tebow... 😱😭

CryingJordan's tweet image. Mets fans waking up, finding out they've signed Tim Tebow... 😱😭

Jake Batchelder reposted

"Nothing was funny for Seneca." atmilb.com/ZQgJK7

Four years ago today, home plate umpire Mario Seneca ejected Daytona Cubs ORGANIST Derek Dye after he played Three Blind Mice. @MiLB



Jake Batchelder reposted

#Marlins Giancarlo Stanton Last 215 plate appearances: 11 HR #SFGiants Madison Bumgarner Last 215 plate appearances: 11 HR


Jake Batchelder reposted

MLB opening day. That special time of year when everyone unites to begin 7 straight months of rooting against the Yankees.


Jake Batchelder reposted

For all the Davidson lefty student athletes as well as our very own @GavinViano #lefty #southpaw #catsarewild

Davidson_DAF's tweet image. For all the Davidson lefty student athletes as well as our very own @GavinViano #lefty #southpaw #catsarewild

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