Jake Kelly MD
@jakekellymd
Performance Cardiologist | VO₂ Max, Metabolic Health & Longevity Strategist | Ironman Triathlete | Father of 3 |
قد يعجبك
The day after Thanksgiving is the perfect low-pressure day to move. 15 minutes of Zone 2 is enough to improve insulin sensitivity, nudge VO₂ max, and set the tone for the weekend. It’s not about intensity. It’s about identity.
SGLT2i & cardiometabolic health benefits @scottisaacsmd & @MichaelMindrum nature.com/articles/s4157…
A golden review article on the cardiometabolic benefits of SGLT2 inhibitors. Similar to GLP1a's, this class of type 2 DM medication now has well established and remarkable benefits in protecting the heart and kidneys for those with and without diabetes. nature.com/articles/s4157……
Fiber Diversity. Awesome Review @ProfWhelan sciencedirect.com/science/articl…
How much fibre, and what different types of fibre, are in foods? Not as easy to answer as you might imagine! It can be affected by conditions, ripening, cooking, cultivar and method of analysis Great review paper here from @DrHArmstrong doi.org/10.1016/j.food…
The best Thanksgiving tradition isn’t the meal; it’s the movement before it. Walk. Jog. Trot. Expand your healthspan.
Chronic disease isn’t sudden. It’s patterned. Movement ↓ Sleep ↓ VO₂ ↓ Insulin ↑ Small wins reverse the slope.
Great list @FitFounder. I wonder if post of us should use the $100,000 to buy back our time to achieve 1. 7-8 hours of sleep 2. 30-60 minutes of exercise time daily 3. More friend/family time, i.e., less stress
If I had $100,000 to invest in my health, I'd buy these: - Sauna - Hot tub - Home gym - Air purifier - Meal prep - Cold plunge - Health coach - Water flosser - Standing desk - Under desk treadmill - Functional blood work - Red light therapy lamp - Incandescent light bulbs -…
Graphic illustration of the "resistance" all of us encounter in our "battle" against aging @gbiondizoccai jacc.org/doi/10.1016/j.…
Must-read review in the latest issue of JACC on Social Determinants of Cardiovascular Aging jacc.org/doi/10.1016/j.…
A Sunday walk. A little strength. A few minutes to plan the week. That’s where healthspan lives: in the margins, not the extremes. #Longevity #healthylifestyle
Cardiometabolic health. This is the goal. This is “Prevention Medicine” @gregmushen & @doctorinigo
Wow! I asked Nano Banana pro to create a scientific illustration of our Lactagenesis hypothesis and the 2 studies where we proved that it is an oncometabolite. This illustration compiling our 3 articles looks really good! Lactate is a master regulator of carcinogenesis through…
Reduce ApoB/LDL-C - doesn't matter how - diet (fiber) exercise, sleep, meds @Drlipid
Anecdotal Study of 1 -- Me -- I have chronic stable CAD (CAC > 300 15 years ago). With that and other risk factors I had, I easily would have qualified for inclusion in the VESALIUS CV Trial. Fortunately, as soon as PCSK9i came on the market I went on Repatha and now a decade…
Caffeine levels & Coffee timing. I'm backing up my last cup of joe during the day.
Caffeine late in the day is one of the worst things you can do for your sleep A controlled sleep lab study gave people 400 mg of caffeine at 0, 3, or 6 hours before bed: all timings disrupted sleep Even the 6 hour dose cut total sleep time by ~70 minutes!
Hypertension doesn’t need complicated solutions. Walk daily. Lift twice a week. Sleep 7–8 hours. Small levers, big drops. #Longevity
Metabolic health doesn’t collapse overnight. It whispers. Fasting insulin → TG/HDL → tiredness → hunger → weight → VO₂ drop. Catch the signals early.
VO₂ max predicts how long you live and how well. The good news? You can train it. The return on effort is unmatched. #Longevity #VO2max #ROOL
Weight loss surgery with potential better health outcomes and reduced healthcare costs than GLP-1s? @MWeintraubMD & @AndrewJSauer
Compared with GLP-1 RAs, metabolic bariatric surgery (MBS) was linked to fewer inpatient stays (–25%) 🏥, outpatient visits (–27%) 🩺, and ED visits (–38%) 🚑, in a retrospective real-world analysis. MBS patients showed lower rates of obesity-related comorbidities, including…
I’ve been waking up early again. Not from stress. From alignment. Sometimes your biology tells you when your life is moving in the right direction.
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