Sai Ma
@saima_lab
Assistant Professor @MountSinai || Buenrostro Lab and Regev Lab Alumni || @Broad || @Harvard || single-cell omics || gene regulation
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I am thrilled to announce that I will start my lab as an Assistant Professor in the Department of Genetics and Genomic Sciences @SinaiGenetics at Mount Sinai @IcahnMountSinai and a member of Icahn Genomics Institute @IcahnInstitute this fall!
Thanks so much for the generous support. We are very excited about the new project! @saima_lab
CONGRATS to Glickenhaus Research Scholar Awardees @wuzhengherbert & Sai Ma👏They aim to uncover how Fos family transcription factors mediate neural activity-dependent changes in gene expression, linking addiction-driven behaviors to molecular mechanisms👉icahn.mssm.edu/research/fried…
Glad to partner with Church Lab on finding a strategy to combat aging! Leveraging a human skin single cell atlas and we found a TF ATF3, an essential target in rejuvenating both epidermis and dermis through cell-cell interactions. Hope to say goodbye to aged skin :)
"Aged Skin? Hope Not Anymore!" Meet our technology from Church lab by experts from various disciplines @geochurch @saima_lab @rohitarorayyc @XaviRNA , "Human skin rejuvenation via mRNA," an innovative mRNA-based treatment to mitigate the effects of skin aging by targeting skin…
Super! Congratulations!
📢 Our latest paper is out in @CellCellPress! Led by the multi-talented @XinheZheng, we accelerated AAV-based gene delivery to 2 days & enabled in vivo CRISPR screens with single cell-level readout, a leap from existing capabilities 🤯 How does it work? (1/8)
Huge congratulations!
GoT-ChA! I am thrilled to announce that our paper "Mapping Genotypes to Chromatin Accessibility Profiles in Single Cells" is now out in @Nature !! 👩🔬👨🔬🧬If you want to link somatic mutations to epigenetic changes directly in patient samples: nature.com/articles/s4158… 👇🧵
Come join us and do some fun science!
Exciting joint postdoc position available!👇Join us & @saima_lab in applying spatial & multi-omics to study neural and genetic/epigenetic dynamics in cognition @SinaiBrain! Experimental background preferred. Competitive salary & subsidized housing provided. Retweets appreciated!
Check out this new single cell methylation approach from my PhD lab!
Droplet-based bisulfite sequencing for high-throughput profiling of single-cell DNA methylomes biorxiv.org/cgi/content/sh… #biorxiv_genomic
We then asked how loss of mSWI/SNF affects chromatin accessibility using SHARE-seq in a wonderful collaboration with @saima_lab and @JD_Buenrostro 🙏8/n
Our new preprint is out! A new computational tool to understand the chromatin-bind proteins using large-scale scATAC data
Single-cell ATAC-seq finds active regulatory elements across cell types, but its resolution can be limited. What if we could identify when and where proteins bind to chromatin? Introducing PRINT, a new single-cell footprinting tool from @JD_Buenrostro lab biorxiv.org/content/10.110…
I am delighted to be invited to IICD! Fantastic people, science, and environment! Looking forward to more interactions.
Another great talk in our seminar series. Thank you to Sai Ma (@saima_lab) from @SinaiGenetics for sharing details about his research and career path with our trainees and researchers.
Super excited to see this out and be part of the team!
Thrilled to share my primary PhD work: a Transcription Factor Atlas for understanding gene regulation and cell engineering @CellCellPress. We created a comprehensive TF ORF library and applied it to profile resulting expression changes. A thread 1/X sciencedirect.com/science/articl…
We are kicking off the new year with the first #FacultyHighlight of 2023. Dr. Sai Ma (@saima_lab) is a new addition to @IcahnMountSinai and an internal member of @SBDRCatMtSinai. His lab is recruiting graduate students and postdocs - definitely an excellent team to work with!
Check out how @JD_Buenrostro pairs chromatin accessibility information with gene expression across cells @HSCRB @Harvard @CellGenomics #ATACseq hscrb.harvard.edu/news/new-techn…
Super excited to see this work is out!
Congratulations to all authors and our amazing collaborators! Wen Yuan @Kwanhoya415 @saima_lab @Ashwins_shetty @JD_Buenrostro Michael Ziller @LodatoS_Lab @jzlevin Alexander Meissner and more!🙌
Join us and work on exciting science at Mount Sinai! Def reach out if you are interested!
Open postdoc positions with the Ma Lab in Single-Cell Biology! Research directions include technology development, gene regulation, cell fate mapping, and disease mechanism investigation. Learn more at: saimalab.com/index.php/join… @saima_lab #postdocs #postdocjobs #genetics
#Preprint Alert from our very own @Jin_Q_Cheong, a 5th yr PhD candidate in @WCM_IMP, and @arjunrshankar, a post-doc in the lab, on long-lasting epigenetic memory of #COVID19 in hematopoietic stem cells and their mature progeny cells! #thread 1/
Epigenetic Memory of COVID-19 in Innate Immune Cells and Their Progenitors biorxiv.org/cgi/content/sh… #bioRxiv
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