saurabhology's profile picture. Trying to understand how Lipids regulate Retinal metabolism ๐Ÿ‘๏ธ @lvprasadeye

Saurabh

@saurabhology

Trying to understand how Lipids regulate Retinal metabolism ๐Ÿ‘๏ธ @lvprasadeye

Saurabh reposted

Alzheimer's-related cognitive decline could be slowed by taking as few as 3000 steps a day, possibly due to the effects of regular exercise on brain health newscientist.com/article/250263โ€ฆ


Saurabh reposted

#NatMetabPicks | In @Cell_Metabolism led by @DominiqueLangin (@Inserm) Hormone-sensitive lipase localizes to the nucleus in adipocytes and regulates adipose tissue homeostasis independently of its cytosolic function. cell.com/cell-metabolisโ€ฆ


Saurabh reposted

Online Now: SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis dlvr.it/TNbfDK

MolecularCell's tweet image. Online Now: SLC25A45 is required for mitochondrial uptake of methylated amino acids and de novo carnitine biosynthesis dlvr.it/TNbfDK

Saurabh reposted

New Online! Transforming cell-surface signatures into customizable protein functions bit.ly/4oUWc21

NatRevMCB's tweet image. New Online! Transforming cell-surface signatures into customizable protein functions bit.ly/4oUWc21

Saurabh reposted

In a world first, a bespoke gene-editing therapy benefitted one child. Now reseachers plan to launch a clinical trial of the approach go.nature.com/47v4czt


Saurabh reposted

People who receive stem cell therapy within a week of their first heart attack have nearly a 60 per cent lower risk of developing heart failure years later newscientist.com/article/250208โ€ฆ


Saurabh reposted

CRISPR-based tools canโ€™t easily access the DNA in mitochondria, but researchers are finding other ways in go.nature.com/4naeHhG


Saurabh reposted

Obituary: John Gurdon (1933-2025) Biologist who made cloning possible go.nature.com/4oyd8eC


Saurabh reposted

When athletes devote large amounts of energy to running or cycling, they unconsciously cut back on energy output elsewhere go.nature.com/47fZPbt


Saurabh reposted

Nature research paper: Spatial metabolic gradients in the liver and small intestine go.nature.com/4n5QMzO


Saurabh reposted

In a new @ScienceAdvances study, Andrew Ward (@WardLab1) and James Ferguson highlight a method that uses cryoEM and the AI tool ModelAngelo to rapidly identify the most protective monoclonal antibodies, cutting discovery time from weeks to under a day and accelerating pandemicโ€ฆ

scrippsresearch's tweet image. In a new @ScienceAdvances study, Andrew Ward (@WardLab1) and James Ferguson highlight a method that uses cryoEM and the AI tool ModelAngelo to rapidly identify the most protective monoclonal antibodies, cutting discovery time from weeks to under a day and accelerating pandemicโ€ฆ

Saurabh reposted

Why does the naked mole rat have the longest lifespan and healthspan of any rodent, nearly 40 years? A 30-year long mystery unraveled @ScienceMagazine today! Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressingโ€ฆ

EricTopol's tweet image. Why does the naked mole rat have the longest lifespan and healthspan of any rodent, nearly 40 years?
A 30-year long mystery unraveled @ScienceMagazine today!
Its cGAS enzyme in cells has 4 missense mutations that upends its function, promoting DNA repair and suppressingโ€ฆ

Saurabh reposted

Why do we age? Evolutionary theory of antagonistic pleiotropy (AP) suggests: genes that enhance reproduction early in life often harm survival later. Is their evidence in humans? We asked do early menarche & early childbirth accelerate aging? 1/n elifesciences.org/articles/102447


Saurabh reposted

๐Ÿšจ Big news from @SusztakLab! Our paper is out in @NatureGenet: "From Million-Cell Atlases to One-Patient Reports" ๐Ÿงฌ๐Ÿง‘โ€โš•๏ธTogether with biostats wizard @NancyRZhang and physician-scientist trainee @KonstantinKltz, we built a cross-species single-cell kidney atlas and analyticsโ€ฆ

KSusztak's tweet image. ๐Ÿšจ Big news from @SusztakLab! Our paper is out in @NatureGenet: "From Million-Cell Atlases to One-Patient Reports" ๐Ÿงฌ๐Ÿง‘โ€โš•๏ธTogether with biostats wizard @NancyRZhang and physician-scientist trainee @KonstantinKltz, we built a cross-species single-cell kidney atlas and analyticsโ€ฆ

Saurabh reposted

I am honored to be named a 2025 ASCB Fellow! It is a privilege to be part of the ASCB community. ASCB was the first conference I attended as a grad student, and it has always been a welcoming, supportive home. Thank you for this kind recognition! โ˜บ๏ธ ascb.org/society-news/fโ€ฆ

ascb.org

Fourteen Visionary Scientists Named 2025 ASCB Fellows - ASCB

The American Society for Cell Biology (ASCB) is proud to announce the election of 14 outstanding scientists as 2025 ASCB Fellowsโ€”a prestigious honor recognizing their exceptional contributions to...


Saurabh reposted

A brief summary of our lab work and mission. So much more to do!

Stanford neuroscientist @Sergiu_P_Pasca is pioneering technology to recreate human brain tissue and neural circuits in the lab โ€” giving scientists unprecedented access to human brain development and opening new possibilities for treating disorders from psychiatric disease toโ€ฆ

Stanford's tweet image. Stanford neuroscientist @Sergiu_P_Pasca is pioneering technology to recreate human brain tissue and neural circuits in the lab โ€” giving scientists unprecedented access to human brain development and opening new possibilities for treating disorders from psychiatric disease toโ€ฆ


Saurabh reposted

Thank you Michael for your amazing leadership and for recognizing the relevance of our work. We really appreciate your support

Nice work in mice and humans demonstrating that apolipoprotein M may attenuate age-related macular degeneration. #NIHfunded @washumedicine @Certimlee @aptelab @WashUMedDOVS @NatureComms paper: brnw.ch/21wU2ZA

NEIDirector's tweet image. Nice work in mice and humans demonstrating that apolipoprotein M may attenuate age-related macular degeneration. 

#NIHfunded @washumedicine @Certimlee @aptelab @WashUMedDOVS 
@NatureComms paper: brnw.ch/21wU2ZA


Saurabh reposted

Nice work in mice and humans demonstrating that apolipoprotein M may attenuate age-related macular degeneration. #NIHfunded @washumedicine @Certimlee @aptelab @WashUMedDOVS @NatureComms paper: brnw.ch/21wU2ZA

NEIDirector's tweet image. Nice work in mice and humans demonstrating that apolipoprotein M may attenuate age-related macular degeneration. 

#NIHfunded @washumedicine @Certimlee @aptelab @WashUMedDOVS 
@NatureComms paper: brnw.ch/21wU2ZA

Saurabh reposted

Excited to share our latest work showing that glycogen accumulates in Tauopathy - and breakdown of glycogen rescues neurodegeneration and reduces ROS

Neurons burn #sugar differently. The discovery from the Kapahi lab could save the brain. Study in @NatMetabolism provides new approach in #Alzheimers research and could explain why #GLP1 drugs show promise against #dementia buckinstitute.org/news/neurons-bโ€ฆ @kapahi_pankaj @KapahiLab



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