#isoforms search results
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
Cool discussion on #3rdgenseq #isoforms #transcripts #alternativesplicing #genomeassembly #longreads with @ISBSIB @markrobinsonca
"Internet cognitive isoforms are cognitive illusions -- similar to optical illusions but involves thinking instead of seeing something that is not real or is a distortion of reality." ~ @TahirRahmanMD #Isoforms #Beliefs #EOB
"On social media, the more 'views' or 'likes' (thumbs ups, hearts) that a social media post receives, the more it is believed — even if it is wrong -- allowing the growth and nurturance of internet cognitive isoforms." ~ @TahirRahmanMD #SocialMedia #Isoforms #Psychology
Won one of the poster prizes at the p53/p63/p73 #isoforms conference!!! 🤩🤩 Quite unexpected, as there isn't a lot of data to show. Still happy to know that my scientific discussion skills are improving! Yay 💯 #gradlife #academics
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
Day 1 at the #RNAUK2022 meeting. Great talks on splicing #isoforms and exciting new #Bioinformaticstools Thanks to the organising committee: @RolandA64475798 @unibirmingham
Ushijima et al. show a role for #phytochromes in regulation of alternative #promoter usage, resulting in light-dependent protein #isoforms with altered subcellular localization that help the plant respond metabolically to fluctuating light conditions. bit.ly/2iaOFgB
Sequence full-length #isoforms with greater sensitivity and efficiency than ever before. Introducing ISO-SEQ , the latest technology from GENEWIZ on our new @PacBio® Sequel® platform. Read about it here. hubs.ly/H09rzj_0
Generated ~80-100mln reads per @nanopore PromethION flow cell @keygene using @WobbleGenomics normalized cDNA on 🌱 samples. Below you see an image of the effect on 5 most abundant spike-in control transcripts. #isoforms #annotation #raretranscripts
Join a session of our live webinar series to learn how the SMART-Seq Pro® Application Kit and ICELL8® cx system facilitate detection of #isoforms, #genefusions, and SNPs with #singlecell #RNAseq. Review the live webinar schedule and register now: ow.ly/A9VM50JenqB
“How different are protein #isoforms from the same gene? What isoforms are expressed? How can we study multiple dimensions of isoform function?” Gloria Sheynkman, PhD @GSheynkman of @DanaFarber is sharing her research on #SystemsBiology approaches to study protein isoforms.
The MAS-Seq method applies the power of #HiFisequencing to single-cell RNA sequencing to identify full-length #isoforms with high accuracy. #PacBio #ASHG22
A high-resolution #quantitative #proteomics map of post-translational modifications on multiple #isoforms of #Tau reveals the importance of PTMs in #Alzheimer’s #disease. Resource article online now! bit.ly/36xpUDE
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gI0meZ
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gHZ1VO
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
N-Terminal deleted isoforms of E3 ligase RNF220 are ubiquitously expressed and required for mouse muscle differentiation doi.org/10.1016/j.moce… #Isoforms #MuscleDifferentiation #Neurodegeneration #RingFingerProtein220 #Variants
Indeed a nice cool study, @syncellbiolab, @anubhav_dhar, @SuchetaDey69384, @MullickSan22454, @Nishaant_PB, @deepak_iisc and Angana. Wonderful to be collaborating with you on this work and looking at #actin #isoforms in #yeast and #mammalian_cells using #UExM.
Preprint: IntAct-U-ExM enables robust, isoform-specific expansion microscopy of actin networks in yeast and mammalian cells. A cool study led by @anubhav_dhar in collab with @Sudiya14 @deepak_iisc #actin biorxiv.org/content/10.110…
Isoform Switching: A Key to Metabolic Flexibility! 🔄 Cells adapt to nutrient changes 🍽️ by regulating isoform usage 🔬, fine-tuning metabolic responses for survival & efficiency ⚖️. #Metabolism #GeneRegulation #Isoforms #Biotech #PrecisionMedicine cell.com/cell-metabolis…
cell.com
Isoform usage as a distinct regulatory layer driving nutrient-responsive metabolic adaptation
Transcriptome modulation is essential for metabolic adaptation to nutrient environments; however, the role of isoform usage is not yet fully understood. Here, Li et al. outline the landscape of...
In this new article we explore TAMA Merge, a powerful tool within #OmicsBox 3.3. that enables researchers to combine novel #isoforms from different conditions into a unified #transcriptome, ensuring even rare isoforms are accurately captured. biobam.com/combining-tran…
"Internet cognitive isoforms are cognitive illusions -- similar to optical illusions but involves thinking instead of seeing something that is not real or is a distortion of reality." ~ @TahirRahmanMD #Isoforms #Beliefs #EOB
"On social media, the more 'views' or 'likes' (thumbs ups, hearts) that a social media post receives, the more it is believed — even if it is wrong -- allowing the growth and nurturance of internet cognitive isoforms." ~ @TahirRahmanMD #SocialMedia #Isoforms #Psychology
A recent @ScholarRock article highlights the value in developing highly-specific antibodies that differentiate between #isoforms and latent forms. Read how their LTBP-49247 #antibody selectively binds & inhibits latent TGF-β1. science.org/doi/10.1126/sc…
Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer. #LongRead @nanopore #RNA #Isoforms #Sequencing #OvarianCancer @NatureComms nature.com/articles/s4146…
nature.com
Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
Nature Communications - Long-read sequencing allows the detection of RNA isoforms, but is hampered by low throughput and potential artefacts. Here, the authors develop the scTaILoR-seq...
R2Dtool github.com/comprna/R2Dtool for handling, integrating, and viualising isoform-resolved RNA feature data - led by @_AJSethi #bioinformatics #RNA #isoforms academic.oup.com/bioinformatics…
I forgot to add that SCALPEL predictions can be experimentally validated. So, for your next #scRNAseq project, remember to quantify transcript #isoforms! #SCALPEL #singlecell #newtool
🚨 New preprint from the @PlassLab !! Really happy to present #SCALPEL, a fast and easy-to-use tool for isoform quantification at the single-cell level! #scRNAseq #isoforms #singlecell #nextflow @p_cmrc @idibell_cat biorxiv.org/content/10.110…
🚨 New preprint from the @PlassLab !! Really happy to present #SCALPEL, a fast and easy-to-use tool for isoform quantification at the single-cell level! #scRNAseq #isoforms #singlecell #nextflow @p_cmrc @idibell_cat biorxiv.org/content/10.110…
A single human #gene can produce multiple different #RNA and protein molecules, called #isoforms, allowing it to perform multiple functions. Long-read sequencing helps @UKSBCoA researchers identify and measure these RNA isoforms from a single gene across.. rna-seqblog.com/long-read-rna-…
Scientists at the @universityofky used a cutting-edge technology called @nanopore #PromethION. This powerful tool allows for the sequencing of long strands of #RNA, providing a detailed picture of the different RNA #isoforms present in each sample. rna-seqblog.com/mapping-medica…
rna-seqblog.com
Mapping medically relevant RNA isoform diversity in the aged human frontal cortex with deep...
In the quest to understand and treat neurological diseases, scientists are investigating RNA isoforms. These are different versions of RNA produced from the same gene, and they can play distinct...
Next week at #nanoporeconf PhD Researcher Sofia Kudasheva will be discussing her work using a combined #sequencing approach to identify novel #isoforms in the study of neurodevelopmental disorders. okt.to/k3mqY2 @nanopore @kudasonya1 @WHaerty
Next month at #nanoporeconf PhD Researcher Sofia Kudasheva will be discussing her work using a combined #sequencing approach to identify novel #isoforms in the study of neurodevelopmental disorders. okt.to/uYJO8v @nanopore @kudasonya1 @WHaerty
Researchers at @WeillCornell performed this massive undertaking in a manner that recorded each individual cell and the long read #RNA sequences it produces. This allowed the researchers to identify #isoforms from hundreds of thousands of individual... rna-seqblog.com/new-atlas-of-m…
rna-seqblog.com
New atlas of mRNA variants captures inner workings of the brain
Investigators at Weill Cornell Medicine have assembled the most comprehensive atlas to date of messenger RNA (mRNA) variants in the mouse...
ScIsoX: a multidimensional framework for measuring isoform-level transcriptomic complexity in single cells. #SingleCell #scRNAseq #Isoforms @GenomeBiology genomebiology.biomedcentral.com/articles/10.11…
Cool discussion on #3rdgenseq #isoforms #transcripts #alternativesplicing #genomeassembly #longreads with @ISBSIB @markrobinsonca
Ushijima et al. show a role for #phytochromes in regulation of alternative #promoter usage, resulting in light-dependent protein #isoforms with altered subcellular localization that help the plant respond metabolically to fluctuating light conditions. bit.ly/2iaOFgB
"Internet cognitive isoforms are cognitive illusions -- similar to optical illusions but involves thinking instead of seeing something that is not real or is a distortion of reality." ~ @TahirRahmanMD #Isoforms #Beliefs #EOB
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
A high-resolution #quantitative #proteomics map of post-translational modifications on multiple #isoforms of #Tau reveals the importance of PTMs in #Alzheimer’s #disease. Resource article online now! bit.ly/36xpUDE
You can do more with MAS-Seq. Understand cell heterogeneity, accurately capture UMIs and identify full-length #isoforms. One MAS-Seq kit comes with reagents to characterize a 3,000 - 10,000 cell single-cell #RNAseq experiment. #PacBio #ASHG22
Sequence full-length #isoforms with greater sensitivity and efficiency than ever before. Introducing ISO-SEQ , the latest technology from GENEWIZ on our new @PacBio® Sequel® platform. Read about it here. hubs.ly/H09rzj_0
Identify & characterise novel #isoforms, novel driver mutations, & #cancer fusion genes with @PacBio #MASSeq Kits! There's still #24hrs⏰ to take advantage of our 50% OFF offer for new users! ➡️Contact Steven for pricing: [email protected] #Genomics #SingleCell
"On social media, the more 'views' or 'likes' (thumbs ups, hearts) that a social media post receives, the more it is believed — even if it is wrong -- allowing the growth and nurturance of internet cognitive isoforms." ~ @TahirRahmanMD #SocialMedia #Isoforms #Psychology
Join a session of our live webinar series to learn how the SMART-Seq Pro® Application Kit and ICELL8® cx system facilitate detection of #isoforms, #genefusions, and SNPs with #singlecell #RNAseq. Review the live webinar schedule and register now: ow.ly/A9VM50JenqB
We're currently offering 50% off @PacBio MAS-Seq Kits for new users! With #MASSeq you can identify & characterise novel #isoforms, novel driver mutations, & #cancer fusion genes. mscience.com.au/view/promotion…
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gHStX9
Day 1 at the #RNAUK2022 meeting. Great talks on splicing #isoforms and exciting new #Bioinformaticstools Thanks to the organising committee: @RolandA64475798 @unibirmingham
“How different are protein #isoforms from the same gene? What isoforms are expressed? How can we study multiple dimensions of isoform function?” Gloria Sheynkman, PhD @GSheynkman of @DanaFarber is sharing her research on #SystemsBiology approaches to study protein isoforms.
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gI0meZ
#Isoforms of Fas - one is, one isn't #apoptotic - balanced by an #RNA binding #protein #RBM5 - through #spliceosome buff.ly/2gHZ1VO
A big part of the project was devoted to define the origins of the splicing #isoforms that shape the TAD of NF-YA across vertebrates. 🔎 For example, we found that #sharks probably lost the main alternatively spliced exon of NF-YA (implications on bone formation?) 🦈 (6/8)
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