#oxphos search results
Mitochondriaの主な役割は脂質のβ酸化でありATP生成能力は二次的なものにすぎない? glucose代謝がpentoseリン酸経路(PPP)および小胞体上のmitochondria外酸化的リン酸化とclosed loopとして結合している可能性 #oxphos #mitochondria doi.org/10.1016/j.bioc…
The increase in abnormal #mitochondria and impaired #OXPHOS may happen due to a reduced amount of the mitochondrial CL. More: lipotype.com/lipidomics-res… #research #lipid #lipidomics #LipidMetabolism #lipotype #lipidome #MassSpectrometry #cardiolipin #arabidopsis
•Human ApoE4 astrocytes display increased glycolytic activity & reduced #OXPHOS •ApoE4 induces defective #autophagy & #mitochondrial dysfunction in human astrocytes •Mitigating #cholesterol burden restores mitochondrial respiration in ApoE4 astrocytes sciencedirect.com/science/articl…
The mitochondrial respiratory chain (MRC) produces 90% of the ATP or chemical cell energy in the human body. Any dysfunction in this chain causes a group of rare diseases called #Oxphos, which mainly affect the heart🫀, lungs🫁 and brain🧠.
Scientists highlighted the pivotal roles of fatty acid oxidation-fueled #OXPHOS and NRF2 in LN #metastasis and suggested targeting these pathways as a promising therapeutic strategy for metastatic esophageal squamous cell carcinoma. @PNASNews | pnas.org/doi/10.1073/pn…
Reminder: Canola oil and inorganic iron-filled grain products are not the same as fruit. Fructose > #OXPHOS
#OXPHOS, CrCEST MRI & proton MR spectroscopy ft. Ryan Armbruster, Dushyant Kumar, Blake Benyard, Paul Jacobs, Ravi Nanga, Neil Wilson, Ravinder Reddy (@PennRadiology), Fang Liu (@UPennDBEI), @MccormackShana (@ChildrensPhila) & @annecappolamd (@PennIDOM) tinyurl.com/9kff9uax
synapse可塑性に於るenergy代謝 synapse可塑性誘導後supine ATPは1.5倍に増加、この増加は可塑性誘導supineから10μm以内に限定される ATP増加はmitochondria(Mit)のOXPHOSに依存しsupine刺激によるCa流入がMit Ca取込みを介しATP合成を促進 #synapse #OXPHOS #papers doi.org/10.1101/2025.0…
Platelet function & blood clotting depend on mitochondria: —Mitochondrial #OXPHOS generates the energy for responding to environmental stress & vascular damage —#MitochondrialDysfunction yields reduced oxygen consumption & reduces platelets Cell Rep 2023 doi.org/10.1016/j.celr…
•Mitochondrial gene expression is required for platelet activation •ELAC2 is essential for platelet function •PTCD1 and MTIF3 are essential for megakaryocyte function & platelet aggregation •Loss of mitoch RNA-binding proteins leads to thrombocytopenia & excessive bleeding
#InsulinResistance is just an emergency. Imagine you are driving a car and you step on the gas (insulin). You expect an increase in engine speed, acceleration, but nothing. The red light on the dashboard lights up and the car goes into emergency mode (activates HIF1a). #OXPHOS
📢New Study📖in Print Coordinated transcriptional upregulation of oxidative metabolism proteins in long-lived endocrine mutant mice by Ahmed M. Elmansi & Richard A. Miller. link.springer.com/article/10.100… @umichmedicine #longevity #βoxidation #oxphos #mitochondria #ncor1 #ghrko
Glad to share a FREE LINK to our @ImmunityCP by @SWculek et al. #OXPHOS #metabolism is differentially used and required for maintenance by #macrophages in tissues (TMFs), depending on the organ and the homeostatic or inflammatory state (1/12) authors.elsevier.com/a/1gXO13qNrUu3…
Patients w/cervical cancer need more people advocating for them & @JulieSchwarz14 has devoted her career to doing just that, getting all the way down to the molecular level and back to the patient. Plus, #oxphos #warburgeffect for the metabolism nerds don’t miss this lecture!
Don't miss this special @SitemanCenter #gynonc lecture by Dr. @JulieSchwarz14 - on @WUSTLmed campus 5/24. "Advancing personalized medicine approaches in #CervicalCancer"
We're looking for an intern student (Master's or equivalent level) to work with me on the #dynamics of the #OXPHOS system in #cellular #senescence in @KarolaSzczepan1 lab @IMol_Institute! Project funded by @NCN_PL Details: euraxess.ec.europa.eu/jobs/143533 Please, spread the word!
If you are curious about #cancermetabolism and #AML_leukemia vulnerabilities, check out our last article published in Cancer Research @CR_AACR by Griessinger et al @emmanuelgriess1, describing a unique sensitivity of #OxPhos AML LSCs to a 4°C cold shock. aacrjournals.org/cancerres/arti…
Check ⬇️ the latest story on #mitochondrialdisorders from the @jourdainlab led by our favorite MD and DJ Marcell Harhai 🎉 Very interesting approach showing how different nutrient sensitive #CRISPR screens compliment each other and highlight new genes required for #OXPHOS
Our updated inventory of genes required for #OXPHOS & findings on #mito defects in #Menieres is now out at @CellReports! 🎉 🧫 New galactose #CRISPR screen 🎯 481 genes required for #OXPHOS ⚙️ #FAM136A in IMS proteostasis 👂 Mito defects in #Menieres cell.com/cell-reports/f…
🔬 Investigadores del @CNIC_CARDIO liderados por José Luis Cabrera y José Antonio Enríquez, @GenoxphosLab, desvelan la evolución del sistema energético celular #OxPhos, el motor vital de nuestras células. Además, han desarrollado ConScore, una herramienta clave para detectar…
What's ironic about Mexican Coke is that instead of citric acid they use... Wait for it.... phosphoric acid! LOL Like and share if you get it #Metabolism #OxPhos #TND
synapse可塑性に於るenergy代謝 synapse可塑性誘導後supine ATPは1.5倍に増加、この増加は可塑性誘導supineから10μm以内に限定される ATP増加はmitochondria(Mit)のOXPHOSに依存しsupine刺激によるCa流入がMit Ca取込みを介しATP合成を促進 #synapse #OXPHOS #papers doi.org/10.1101/2025.0…
Scientists highlighted the pivotal roles of fatty acid oxidation-fueled #OXPHOS and NRF2 in LN #metastasis and suggested targeting these pathways as a promising therapeutic strategy for metastatic esophageal squamous cell carcinoma. @PNASNews | pnas.org/doi/10.1073/pn…
Evidence implicating disturbed #muscle #mitochondria #OXPHOS #proteome and #NAD+ #homeostasis in experimental #cancer #cachexia sciencedirect.com/science/articl… #ACVR #Serpina3N #activin #Nrk2
Review ▪ #MitochondrialDisorders of the #OXPHOS system →febs.onlinelibrary.wiley.com/doi/10.1002/18… #mitochondria #metabolism #cytochrome #inbornerrorsofmetabolism #respiratorychain #neurodevelopment
Altered mitochondrial dynamics in #PancreaticCancer Mitochondrial fusion as a novel tumor suppressor mechanism @TaniguchiMD @MDAndersonNews on a roll with a new @biorxivpreprint biorxiv.org/content/biorxi… #Metabolism #OXPHOS #RadOnc
The increase in abnormal #mitochondria and impaired #OXPHOS may happen due to a reduced amount of the mitochondrial CL. More: lipotype.com/lipidomics-res… #research #lipid #lipidomics #LipidMetabolism #lipotype #lipidome #MassSpectrometry #cardiolipin #arabidopsis
Scientists highlighted the pivotal roles of fatty acid oxidation-fueled #OXPHOS and NRF2 in LN #metastasis and suggested targeting these pathways as a promising therapeutic strategy for metastatic esophageal squamous cell carcinoma. @PNASNews | pnas.org/doi/10.1073/pn…
•Human ApoE4 astrocytes display increased glycolytic activity & reduced #OXPHOS •ApoE4 induces defective #autophagy & #mitochondrial dysfunction in human astrocytes •Mitigating #cholesterol burden restores mitochondrial respiration in ApoE4 astrocytes sciencedirect.com/science/articl…
Mitochondriaの主な役割は脂質のβ酸化でありATP生成能力は二次的なものにすぎない? glucose代謝がpentoseリン酸経路(PPP)および小胞体上のmitochondria外酸化的リン酸化とclosed loopとして結合している可能性 #oxphos #mitochondria doi.org/10.1016/j.bioc…
Before you diffuse tomorrow, check out our two talks in the immunity session..feedback welcomed...#mitos #oxphos #cellDeath #evo #ASCBEMBO19
🚨New Study Alert🚨 Check out @biorxivpreprint from H. Fujiwara, Reddy Lab @umichmedicine. Autoreactive T cells Repress #OXPHOS in intestinal epithelial cells by down-regulating #SDH. Exciting collaboration! Huge therapeutic potential for #GVHD. #IBD. biorxiv.org/content/10.110…
Paper in Press: "HIGD2A is required for assembly of the COX3 module of human mitochondrial complex IV" – #OxPhos #Mitochondria #respirasome mcponline.org/content/early/… @unimelb
Happy and proud to share our newest study describing the metabolic flexibility of #skeletal #progenitors: they respond to #OXPHOS block by reversing SDH and using alternative NAD+ regeneration to preserve #proliferation, #stemness and improve #bone repair. (1/3)
We're looking for an intern student (Master's or equivalent level) to work with me on the #dynamics of the #OXPHOS system in #cellular #senescence in @KarolaSzczepan1 lab @IMol_Institute! Project funded by @NCN_PL Details: euraxess.ec.europa.eu/jobs/143533 Please, spread the word!
In Science #Immunology: #OXPHOS promotes #Bcell pro-inflammatory cytokine production by regulating ATP signaling in #MultipleSclerosis. @PennMedicine @HMU_UNI scim.ag/6Rd
The #OXPHOS metabolic pathway regulates pro-inflammatory signaling in #MultipleSclerosis-patient #Bcells and #neuroinflammation in mice. @PennMedicine @HMU_UNI Learn more: scim.ag/6TI
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