Anatomic Incorporated
@AnatomicTech
Not Your Average Neuron™ Rapid production of human induced pluripotent stem cell-derived nociceptors for research and therapeutic applications.
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🎥 A glimpse into our 7-day directed differentiation of human iPSC-derived dorsal horn neurons. Fast. Reproducible. Ready for pain pathway discovery. #NotYourAverageNeuron #CompleteTheCircuit #neuroscience #drugdiscovery #iPSC #dorsalhorn #painresearch
Motor neurons alone can't explain ALS or CMT. Schwann Cell Precursors reveal how disrupted glial-neuronal crosstalk drives disease. Co-cultures model early pathogenesis, glial dysfunction, and myelination defects more accurately #CompleteTheCircuit #NotYourAverageNeuron
Add These Publications to Your Reading List📚 Explore all publications featuring Anatomic’s products in one place-a fast way to find relevant assays & new applications See how our models are advancing discovery: anatomic.com/publications #CompleteTheCircuit #NotYourAverageNeuron
The Kolber Lab at UTD has launched a core facility featuring a high-content screening assay for analgesic discovery using the Axion BioSystems Maestro Pro, now featured in their latest publication Read the article here: cell.com/cell-reports-m…
Team Anatomic hit the pavement together for the #Walk4CMT 💙 Grateful to be part of a community that's raising awareness, showing support, and walking toward a cure. Huge to @cmtausa for putting on a well organized and meaningful event!
Keepin it local🤙🏼Attended the 3rd MN Organoid Symposium put on by the @umnmedschool & @MayoClinic earlier this week. Big shoutout to our Scitech intern Devanshi who gave her first poster presentation! Reach out to learn more about applications in this space➡️[email protected]
🌉Vince will be speaking at the @AxionBioSystems World Tour: San Francisco User Group Meeting on April 17, 2025! 🎤“Completing the Circuit: Advanced hiPSC-Based Models of the Peripheral Nervous System for Disease Modeling and Drug Discovery" 🔗Register axionbiosystems.com/axion-world-to…
💡 Enhance your research! Integrate Schwann cell precursors (SCPs) into your motor neuron (MNs) cultures As SCPs mature, they migrate & align along axons, visualized using immunofluorescent staining—S100b/SOX10 (SCPs) & TUJ1 (MNs) #CompleteTheCircuit #ALSResearch
💎Check-out the purity💎 Images of RealDHN hiPSC-derived dorsal horn neuron cultures, generated without the need for genetic engineering or Mitomycin C treatment Visit anatomic.com/realdhn for more info on the molecular and functional characterization of the neurons!
Anatomic has been focused on developing CIPN-related assays for the last few years. The FDA’s new draft guidance underscores the need for better study designs and endpoints in CIPN research. Read the full guidance below! #CompleteTheCircuit #CIPNResearch
💎Check-out the purity💎 Images of co-cultures of RealSCP, hiPSC-derived Schwann cell precursors, and RealDRG, hiPSC-derived sensory neurons, generated without the need for genetic engineering or Mitomycin C #CompleteTheCircuit #NotYourAverageNeuron
It’s always tough to pick favorites when there’s so much exciting data to explore! 🤩 We have compiled our favorite data from over the years onto a new page for your easy access Check out our data highlights page at: anatomic.com/datahighlights
Harnessing a more physiological in vitro model for CIPN! Dr. Nanna Elman Andersen’s Ph.D. thesis explores chemotherapy-induced neurotoxicity using hiPSC-derived Schwann cells & sensory neurons, studying paclitaxel, vincristine & bortezomib portal.findresearcher.sdu.dk/en/publication…
Science is serious stuff, but sometimes it can’t help but make you smile. Especially when it smiles first 😁
🧒🏻👧🏽👦🏼👩🏽🦱Multiple donors. Same process. Sensory neurons derived from hiPSC lines (both healthy and diseased) express key ion channel targets for pain - NaV1.7, NaV1.8, and TRPV1 #NotYourAverageNeuron #CompleteTheCircuit #DiseaseModeling #PainResearch
🚨New Insights into Chronic Pain 🚨 Reduced KCC2 expression in the dorsal horn links to chronic pain and opioid use. KCC2 regulates chloride gradients for inhibition, and its dysfunction drives neuropathic pain. Findings support therapies targeting KCC2 biorxiv.org/content/10.110…
🔎How do you “spot” a melanocyte? You look with your naked eye! With RealMELO, Anatomic is going MACROSCOPIC! If your drug screen readout is pigmentation, the effects will be obvious in as little as 7 days post-thaw! #CompleteTheCircuit #Vitiligo #Melanoma #Cosmetics
📰RealDRG iPSC-derived nociceptors power a novel axonal electrophysiology platform! Using @mxwbio HD-MEAs + PDMS microstructures, this system aids nociceptor distinction & drug screening for neuropathic pain 🔗 Read more: biorxiv.org/content/10.110… #Pain #TRPV1
🔬👩🔬Twitch isn’t only for gamers. See motor neuron-induced myofiber contraction in our neuromuscular junction (NMJ) assay using Anatomic’s new RealMOTO hiPSC-derived motor neurons! #CompleteTheCircuit #NotYourAverageNeuron #ALS #CMT #StemCells #Microfluidics
Sensory neurons and Schwann cells are better together❣️Whether you are single or have date night plans, this is a scientific love story that you can study this Valentine’s day. #CompleteTheCircuit #NotYourAverageNeuron #PainResearch #CoCultures #CMT
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