AppliedBioPhys's profile picture. Creator of ECIS® 😎 Pioneering impedance-based tools for real-time, label-free cell research and drug discovery. Study cells in vitro with precision and ease.

Applied Biophysics

@AppliedBioPhys

Creator of ECIS® 😎 Pioneering impedance-based tools for real-time, label-free cell research and drug discovery. Study cells in vitro with precision and ease.

Hyperosmolar stress slashed corneal barrier integrity by up to 69%—but L-carnitine helped restore it. With #ECIS Z-Theta, researchers showed: 🔹 NaCl cut TER 30–69% & slowed migration 🔹 L-carnitine partly rescued TER & repair 📄Full Paper: 10.1016/j.exer.2025.110499

AppliedBioPhys's tweet image. Hyperosmolar stress slashed corneal barrier integrity by up to 69%—but L-carnitine helped restore it.

With #ECIS Z-Theta, researchers showed:
🔹 NaCl cut TER 30–69% & slowed migration
🔹 L-carnitine partly rescued TER & repair

📄Full Paper: 10.1016/j.exer.2025.110499
AppliedBioPhys's tweet image. Hyperosmolar stress slashed corneal barrier integrity by up to 69%—but L-carnitine helped restore it.

With #ECIS Z-Theta, researchers showed:
🔹 NaCl cut TER 30–69% & slowed migration
🔹 L-carnitine partly rescued TER & repair

📄Full Paper: 10.1016/j.exer.2025.110499
AppliedBioPhys's tweet image. Hyperosmolar stress slashed corneal barrier integrity by up to 69%—but L-carnitine helped restore it.

With #ECIS Z-Theta, researchers showed:
🔹 NaCl cut TER 30–69% & slowed migration
🔹 L-carnitine partly rescued TER & repair

📄Full Paper: 10.1016/j.exer.2025.110499

Using #ECIS Z-Theta, researchers tracked how Müller glial EVs affect RPE barrier function: 🔵 Normoxic EVs: Barrier stable ✅ 🟡 Hypoxic EVs: Barrier weakens, TER drops over 72h 💡 #ECIS reveals how hypoxic EVs compromise retinal integrity Full paper: mdpi.com/2079-7737/14/8…

AppliedBioPhys's tweet image. Using #ECIS Z-Theta, researchers tracked how Müller glial EVs affect RPE barrier function:

🔵 Normoxic EVs: Barrier stable ✅
🟡 Hypoxic EVs: Barrier weakens, TER drops over 72h 
💡 #ECIS reveals how hypoxic EVs compromise retinal integrity

Full paper: mdpi.com/2079-7737/14/8…

We are saddened to share that our colleague and friend, Dr. Ivar Giaever—Nobel Laureate and co-founder of Applied BioPhysics—passed away peacefully on June 20 at the age of 96. His brilliance, humor, and visionary spirit continue to inspire us. He will be deeply missed. 🕊️💙

AppliedBioPhys's tweet image. We are saddened to share that our colleague and friend, Dr. Ivar Giaever—Nobel Laureate and co-founder of Applied BioPhysics—passed away peacefully on June 20 at the age of 96. His brilliance, humor, and visionary spirit continue to inspire us. He will be deeply missed. 🕊️💙

🔎 TEERZ doesn’t just give more data—it gives better answers. 📉 Same trend as manual TEER, but with: ✅ Real-time, high-res data ✅ Full 96-well tracking ✅ Zero interruptions Why settle for snapshots when you can see the full story? #TEER #TEERZ #ECIS #CellBiology #Biotech

AppliedBioPhys's tweet image. 🔎 TEERZ doesn’t just give more data—it gives better answers.

📉 Same trend as manual TEER, but with:
✅ Real-time, high-res data
✅ Full 96-well tracking
✅ Zero interruptions

Why settle for snapshots when you can see the full story?

#TEER #TEERZ #ECIS #CellBiology #Biotech

🧬 New #GPCR insights via #ECIS! UIC researchers show CLIC1/CLIC4 regulate Rac1 in endothelial cells—not through ion channel activity, but via structural domains (C-termini). 📖 Study: lnkd.in/giTdG6h7 🔍 About ECIS TEER: lnkd.in/gEqFH5Bt #BarrierFunction #TEER

AppliedBioPhys's tweet image. 🧬 New #GPCR insights via #ECIS!
UIC researchers show CLIC1/CLIC4 regulate Rac1 in endothelial cells—not through ion channel activity, but via structural domains (C-termini).

📖 Study: lnkd.in/giTdG6h7
🔍 About ECIS TEER: lnkd.in/gEqFH5Bt

#BarrierFunction #TEER

Discover how ECIS® evolved from a bold scientific idea into a trusted tool that’s transformed live cell research for over 40 years. ⬇️Link below⬇️#ECIS 🧑‍🔬tinyurl.com/3kpprc6n

AppliedBioPhys's tweet image. Discover how ECIS® evolved from a bold scientific idea into a trusted tool that’s transformed live cell research for over 40 years. ⬇️Link below⬇️#ECIS

🧑‍🔬tinyurl.com/3kpprc6n

🧬 Calling all cell biologists & bioengineers! Join us at IBCA 2025 – the 6th Int'l Conference on Impedance-Based Cellular Assays! Register now 👇 📃lnkd.in/gi2dUQQu #IBCA2025 #CellBasedAssays #ECIS #ImpedanceAssays #CellBiology

AppliedBioPhys's tweet image. 🧬 Calling all cell biologists & bioengineers! Join us at IBCA 2025 – the 6th Int'l Conference on Impedance-Based Cellular Assays! Register now 👇

📃lnkd.in/gi2dUQQu

#IBCA2025 #CellBasedAssays #ECIS #ImpedanceAssays #CellBiology

🦠New study from Univ. of Regensburg shows how #ECIS tracks virus-induced cytopathic effects in real time—offering a powerful, non-invasive alternative to traditional neutralization assays. 🔗lnkd.in/gRcFRxcQ #Virology #VirusNeutralization #Biotech #Pseudovirus #Impedance

AppliedBioPhys's tweet image. 🦠New study from Univ. of Regensburg shows how #ECIS tracks virus-induced cytopathic effects in real time—offering a powerful, non-invasive alternative to traditional neutralization assays.

🔗lnkd.in/gRcFRxcQ
#Virology #VirusNeutralization #Biotech #Pseudovirus #Impedance

Exciting new paper from Dr. A. Chowdhury & UQ @MDPIOpenAccess 🧪 Real-time venom research with #ECIS 🐍 Viper & cobra venoms cause cell damage 🛡️ DTIs (varespladib + marimastat) offer protection ⚖️ Supports alternatives to animal testing 📄 Full paper: mdpi.com/2072-6651/17/4…

AppliedBioPhys's tweet image. Exciting new paper from Dr. A. Chowdhury & UQ @MDPIOpenAccess 

🧪 Real-time venom research with #ECIS
🐍 Viper & cobra venoms cause cell damage
🛡️ DTIs (varespladib + marimastat) offer protection
⚖️ Supports alternatives to animal testing

📄 Full paper: mdpi.com/2072-6651/17/4…

Congratulations to Catherine on graduating from SBA THRIVE 🎉We’re proud of her dedication to leadership, growth, and innovation. Her fresh ideas and strategies inspire our team and drive us forward.🚀Here’s to continued success and impact! #Leadership #Innovation #GrowthMindset

AppliedBioPhys's tweet image. Congratulations to Catherine on graduating from SBA THRIVE 🎉We’re proud of her dedication to leadership, growth, and innovation. Her fresh ideas and strategies inspire our team and drive us forward.🚀Here’s to continued success and impact! #Leadership #Innovation #GrowthMindset

Join us for our upcoming webinar: Barrier Function Assays at 11:00 AM EDT on October 15, 2024 ➡️lnkd.in/gn3qbqSb This webinar will discuss how complex impedance measurements with #ECIS can be used to evaluate the barrier function and #TEER of confluent cells.

AppliedBioPhys's tweet image. Join us for our upcoming webinar: Barrier Function Assays at 11:00 AM EDT on October 15, 2024 ➡️lnkd.in/gn3qbqSb

This webinar will discuss how complex impedance measurements with #ECIS can be used to evaluate the barrier function and #TEER of confluent cells.

Watch 🤩our latest video to learn more about #ECIS and follow our page for updates! If you have any questions, let us know in the comments 👩‍🔬 ⏩tinyurl.com/yrnnfrwd


Join us for our upcoming webinar: Automated Cell Migration at 11:00 AM EDT on October 1, 2024 ➡ tinyurl.com/4a5dw93u This webinar will discuss how the #ECIS system employs electric signals to both wound and monitor the healing process of cells. #sciencetwitter


Join us for our upcoming webinar: Cell Invasion/Extravasation Assays @ 11:00 AM EDT -September 17, 2024 ➡ tinyurl.com/mtchyfya Topic: Observe the extravasation of cell layers in real-time and record quantitative data regarding the metastatic potential of the cancer cells.

AppliedBioPhys's tweet image. Join us for our upcoming webinar: Cell Invasion/Extravasation Assays @ 11:00 AM EDT -September 17, 2024  ➡ tinyurl.com/mtchyfya

Topic:  Observe the extravasation of cell layers in real-time and record quantitative data regarding the metastatic potential of the cancer cells.

We are excited to announce we have received a 2-year, $1.8M grant from NIH! 🥳 tinyurl.com/mt7ua5cp The SBIR grant will fund the R&D of the #ECIS Cell Assurance Monitor, a new approach to ensure the quality and integrity of cells grown in vitro. 👩‍🔬🧫


Congrats to our company President, Catherine, for being accepted into the SBA T.H.R.I.V.E. CEO Training Program! She is excited about this opportunity to collaborate with local business owners and learn from business leaders nationwide🥳Huzzah! #smallbiz @ThriveSBA @SBAUpstateNY

AppliedBioPhys's tweet image. Congrats to our company President, Catherine, for being accepted into the SBA T.H.R.I.V.E. CEO Training Program! She is excited about this opportunity to collaborate with local business owners and learn from business leaders nationwide🥳Huzzah! #smallbiz @ThriveSBA @SBAUpstateNY

Fun with Physics Friday! Just a little #ECIS humor 💪 to pump you up before the weekend! #TEER #biology #technology #sciencememes #sciencejokes #ScienceTwitter

AppliedBioPhys's tweet image. Fun with Physics Friday!  Just a little #ECIS humor 💪 to pump you up before the weekend! 

#TEER #biology #technology #sciencememes #sciencejokes #ScienceTwitter

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