The Atkinson Lab
@AtkinsonLab
The Carl Atkinson Lab at Northwestern @NUFeinbergMed. Focuses include transplant immunology, complement biology, innate immunity, & more. Views are our own.
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As always, it was great to spend time with fellow complement scientists at #ICW2023. Proud of PhD candidate @dianna_nord for winning a "best oral presentation" prize for her work on complement in neutrophils. Thanks to @ComplementSoc for a great meeting in Newcastle.
In our latest forum article, @trendscancer, we discussed the critical roles of sphingolipids and the complement system in promoting cancer growth/survival. Check it out authors.elsevier.com/c/1hUGV8Z12yTu…. Thanks, @AtkinsonLab
Fantastic day at #ATC2023SanDiego! Dr. Atkinson delivered two incredible presentations sharing some of the lab's work on 1) complement inhibition in organ Tx and 2) strategies for targeted immunosuppression to the endothelium in lung Tx.
Congratulations to lab alumnus Dr. Danh Tran whose PhD dissertation work has won the AJT Basic Science Paper of the Year Award! @DanhTTran @SatishNadig #ATC2023SanDiego
Our laboratory had an excellent time at #ISHLT2023 in Denver last week! PhD students @dianna_nord and Blake Gill presented some of the lab's work. Always great to learn from and catch up with the @ISHLT community.
We are currently recruiting Post-Doctoral Associates with backgrounds in immunology, complement biology, or transplantation to join our team! Interested candidates - please email your CV to [email protected] to learn more.
A @UF team led by Andrew Judge, Ph.D., Carl Atkinson, Ph.D., & Sarah Judge, Ph.D. has received a $2.3 million grant from the @NIH_NIAMS to investigate strategies to treat muscle wasting and weakness caused by #PancreaticCancer. #CancerCachexia Read more: go.ufl.edu/u9czh7e
We are excited to share our latest publication in the Journal of Immunology @J_Immunol. The work, led by Dr. Jennifer Mulligan, reveals a novel regulatory relationship between complement activation and local vitamin D metabolism in airway epithelial cells. jimmunol.org/content/early/…
2 days into #ATC2022! Yesterday evening, our surgical research fellow Dr. Leah Plumblee presented the lab’s work utilizing ex-vivo treatments to stabilize cell junctions and improve outcomes in a porcine renal transplant model. #ATC2022Boston
Hello from Boston! Our lab members are at #ATC2022 this week to learn & collaborate with others in the transplant field. Today PhD candidate @dianna_nord presented the lab’s work on mitochondrial transplantation in #LTx.
Another patent for @AtkinsonLab and our lab @NM_Transplant on donor organ pre treatment with nanotherapy. One more step closer to the bedside. #sciencerocks
To all early-career complement biology researchers - fill out the ECCO survey! Doing so will help us understand our members' needs and to suggest ideas that will improve the field of complement research for all.
1.) ECCO represents and supports early-career researchers in the field of #complementbiology! In order to do that to the best of our abilities, we want to conduct a survey to identify ECCO members’ interests and needs: bit.ly/3poFv2n Please fill in our 10min-survey!🙏
More evidence supporting the efficacy of targeted complement inhibition! We recently collaborated with Stephen Tomlinson at @MUSChealth to show that P-selectin targeted complement inhibitors specifically localized to reperfused tissue and reduced injury in a murine limb Tx model.
New Research: Characterization of Novel P-Selectin Targeted Complement Inhibitors in Murine Models of Hindlimb Injury and Transplantation: The complement system has long been recognized as a potential druggable target for a variety of… frontiersin.org/articles/10.33… #immunology
We are excited to share our latest publication in collaboration with Dr. @SatishNadig on the immunoprotective effects of altering donor mitochondrial fission/fusion during cardiac transplantation! @amjtransplant doi.org/10.1111/ajt.16…
After contracting COVID-19, Dr. Sean Devine's lungs were scarred & unable to work on their own. He was flown to @UFHealth, one of two places in the U.S. at the time that had successfully performed a COVID-19 double lung transplant. Hear his story of strength, recovery and love.
We recently showed that VCA donor graft treatment pre-transplantation with CR2-Crry provided protection from IRI and delayed graft rejection. The results are published in our new paper with collaborators at @MUSChealth in the lab of Stephen Tomlinson: pubmed.ncbi.nlm.nih.gov/34394069/
We are extremely proud to annonce that lab member Alexander McQuiston successfully defended his PhD Dissertation earlier this month and will be starting as a post-doctoral fellow at Stanford later this fall. Congrats, Dr. McQuiston! You will be missed!
Important work by Sommer et al. showing organ-specific differences in tolerance induction in #transplantation. Why is this important? A “one-size-fits-all” approach in transplantation is unsuccessful, and we can't assume that all organs benefit from the same immunosuppression.
Although the clinically applicable protocol showed success in #kidney transplantation, the study by Sommer et al. did not show long-term survival in a #lung transplant model, highlighting the organ-specific differences in tolerance induction. bit.ly/3eDBCRM
“This surge is actually much bigger than anything that we've seen before.” Dr. Hiren Mehta describes the unbearable conditions inside UF Health Shands Hospital in Gainesville, Florida, as the COVID-19 crisis continues to worsen across much of the South. abcn.ws/2W0QTGe
COMPLEMENT ON THE PIPELINE: complement activation seems to add morbidity to inflammation and pro-thrombotic status in pts on hemodialysis. ⚡️💥Intradialytic Complement Activation Precedes the Development of Cardiovascular Events in Hemodialysis Patients ncbi.nlm.nih.gov/pmc/articles/P…
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