CLebacle's profile picture. Improving patient outcomes & advancing the field. #BladderCancer #RoboticSurgery French Urologist at @Hopital_Bicetre @APHP

Cédric Lebâcle

@CLebacle

Improving patient outcomes & advancing the field. #BladderCancer #RoboticSurgery French Urologist at @Hopital_Bicetre @APHP

Cédric Lebâcle reposted

💥 MIBC is no longer surgery-first—oncology is rewriting the rulebook. 🩺 Surgery & Chemo (traditional backbone) Radical cystectomy ± peri-op cisplatin chemo remains standard, but morbidity & patient fitness limit its universal application. 🧬 Immunotherapy integration…

DrRishabhOnco's tweet image. 💥 MIBC is no longer surgery-first—oncology is rewriting the rulebook.

🩺 Surgery & Chemo (traditional backbone)
Radical cystectomy ± peri-op cisplatin chemo remains standard, but morbidity & patient fitness limit its universal application.

🧬 Immunotherapy integration…

Cédric Lebâcle reposted

Phase II SunRISe-1: TAR-200 (slow drug-releasing system for gemcitabine) achieved CR in 82% of pts with BCG-unresponsive high-risk NMIBC @JCO_ASCO 🩺@siadaneshmand#FDA priority review granted ascopost.com/news/august-20…

ASCOPost's tweet image. Phase II SunRISe-1: TAR-200 (slow drug-releasing system for gemcitabine) achieved CR in 82% of pts with BCG-unresponsive high-risk NMIBC @JCO_ASCO 
🩺@siadaneshmand
❕#FDA priority review granted 
ascopost.com/news/august-20…

Cédric Lebâcle reposted

Heal with steel in cN+ UTUC. 🩹🩹 🇹🇼 Nationwide cohort (n=288): RNU ↓ UTUC-specific mortality 69%→36%, 5-yr CSS 0%→39% vs. no surgery. Surgery still matters N+disease #UroOnc #UTUC nature.com/articles/s4159…

LauraBukavinaMD's tweet image. Heal with steel in cN+ UTUC. 🩹🩹
🇹🇼 Nationwide cohort (n=288): RNU ↓ UTUC-specific mortality 69%→36%, 5-yr CSS 0%→39% vs. no surgery.

Surgery still matters N+disease 
#UroOnc #UTUC nature.com/articles/s4159…
LauraBukavinaMD's tweet image. Heal with steel in cN+ UTUC. 🩹🩹
🇹🇼 Nationwide cohort (n=288): RNU ↓ UTUC-specific mortality 69%→36%, 5-yr CSS 0%→39% vs. no surgery.

Surgery still matters N+disease 
#UroOnc #UTUC nature.com/articles/s4159…

Cédric Lebâcle reposted

💫🌟📢 The impact of radical cystectomy (RC) on sexual health & QoL🌟💫 Presenter: @PignotG | Moderator: @CLebacle #BLADDR24 @OncoAlert @mirrorsmed 🔍 Key Points: 🟠RC impacts sexual function significantly. Yet, 41.2% of urologists avoid discussing sexual outcomes with…

nataliagandur's tweet image. 💫🌟📢 The impact of radical cystectomy (RC) on sexual health & QoL🌟💫
Presenter: @PignotG | Moderator: @CLebacle
#BLADDR24 @OncoAlert @mirrorsmed

🔍 Key Points:

🟠RC impacts sexual function significantly. Yet, 41.2% of urologists avoid discussing sexual outcomes with…
nataliagandur's tweet image. 💫🌟📢 The impact of radical cystectomy (RC) on sexual health & QoL🌟💫
Presenter: @PignotG | Moderator: @CLebacle
#BLADDR24 @OncoAlert @mirrorsmed

🔍 Key Points:

🟠RC impacts sexual function significantly. Yet, 41.2% of urologists avoid discussing sexual outcomes with…
nataliagandur's tweet image. 💫🌟📢 The impact of radical cystectomy (RC) on sexual health & QoL🌟💫
Presenter: @PignotG | Moderator: @CLebacle
#BLADDR24 @OncoAlert @mirrorsmed

🔍 Key Points:

🟠RC impacts sexual function significantly. Yet, 41.2% of urologists avoid discussing sexual outcomes with…
nataliagandur's tweet image. 💫🌟📢 The impact of radical cystectomy (RC) on sexual health & QoL🌟💫
Presenter: @PignotG | Moderator: @CLebacle
#BLADDR24 @OncoAlert @mirrorsmed

🔍 Key Points:

🟠RC impacts sexual function significantly. Yet, 41.2% of urologists avoid discussing sexual outcomes with…

Cédric Lebâcle reposted

💡 Highlights from #BLADDR24: Translating Data into Practice 🚨 Moderators: @CLebacle & Fred Witjes 🔥 Practical insights into intravesical instillation for bladder cancer: @OncoAlert @mirrorsmed Efficacy Tips: Limit voiding before therapy 🚫💧 & drink fluids after 💦. Toxicity…

nataliagandur's tweet image. 💡 Highlights from #BLADDR24: Translating Data into Practice 🚨
Moderators: @CLebacle & Fred Witjes
🔥 Practical insights into intravesical instillation for bladder cancer:
@OncoAlert @mirrorsmed
Efficacy Tips: Limit voiding before therapy 🚫💧 & drink fluids after 💦.

Toxicity…
nataliagandur's tweet image. 💡 Highlights from #BLADDR24: Translating Data into Practice 🚨
Moderators: @CLebacle & Fred Witjes
🔥 Practical insights into intravesical instillation for bladder cancer:
@OncoAlert @mirrorsmed
Efficacy Tips: Limit voiding before therapy 🚫💧 & drink fluids after 💦.

Toxicity…
nataliagandur's tweet image. 💡 Highlights from #BLADDR24: Translating Data into Practice 🚨
Moderators: @CLebacle & Fred Witjes
🔥 Practical insights into intravesical instillation for bladder cancer:
@OncoAlert @mirrorsmed
Efficacy Tips: Limit voiding before therapy 🚫💧 & drink fluids after 💦.

Toxicity…
nataliagandur's tweet image. 💡 Highlights from #BLADDR24: Translating Data into Practice 🚨
Moderators: @CLebacle & Fred Witjes
🔥 Practical insights into intravesical instillation for bladder cancer:
@OncoAlert @mirrorsmed
Efficacy Tips: Limit voiding before therapy 🚫💧 & drink fluids after 💦.

Toxicity…

Cédric Lebâcle reposted

Fantastic talks on practical surgical questions on DAY 2 of #BLADDR24 - Practical aspects of intravesical instillation by Fred Witjes - The optimal TURBT by Ben-Max de Ruiter - The impact of RC on sexual function/experience by @PignotG Moderation: @CLebacle @OncoAlert

mirrorsmed's tweet image. Fantastic talks on practical surgical questions on DAY 2 of #BLADDR24 
- Practical aspects of intravesical instillation by Fred Witjes
- The optimal TURBT by Ben-Max de Ruiter
- The impact of RC on sexual function/experience by @PignotG 

Moderation: @CLebacle 

@OncoAlert
mirrorsmed's tweet image. Fantastic talks on practical surgical questions on DAY 2 of #BLADDR24 
- Practical aspects of intravesical instillation by Fred Witjes
- The optimal TURBT by Ben-Max de Ruiter
- The impact of RC on sexual function/experience by @PignotG 

Moderation: @CLebacle 

@OncoAlert
mirrorsmed's tweet image. Fantastic talks on practical surgical questions on DAY 2 of #BLADDR24 
- Practical aspects of intravesical instillation by Fred Witjes
- The optimal TURBT by Ben-Max de Ruiter
- The impact of RC on sexual function/experience by @PignotG 

Moderation: @CLebacle 

@OncoAlert

Cédric Lebâcle reposted

So fun to debate my friend & colleague @b_szabados on role of ctDNA in #bladdercancer citing data from TOMBOLA IMvigor011, etc. Great moderation by @DanieleRaggi83 @tompowles1 @Uromigos @AndreaNecchi @MattGalsky @JoshMeeks @achoud72 @KilianGust @OncoAlert @mirrorsmed #BLADDR24

💫🌟Debate: The Role of ctDNA in Adjuvant MIBC Management Moderator: Daniele Raggie SUPER PRESENTATION !!👏👏@PGrivasMDPhD, @b_szabados #BLADDR24 @OncoAlert @mirrorsmed 🔸️ctDNA+ post-RC detected in 52% of patients; 75% had recurrence <4 months. 🚨 🔸️Only 3% of…

nataliagandur's tweet image. 💫🌟Debate: The Role of ctDNA in Adjuvant MIBC Management
Moderator: Daniele Raggie 
SUPER PRESENTATION !!👏👏@PGrivasMDPhD, @b_szabados
#BLADDR24  @OncoAlert @mirrorsmed

🔸️ctDNA+ post-RC detected in 52% of patients; 75% had recurrence &amp;lt;4 months. 🚨

🔸️Only 3% of…
nataliagandur's tweet image. 💫🌟Debate: The Role of ctDNA in Adjuvant MIBC Management
Moderator: Daniele Raggie 
SUPER PRESENTATION !!👏👏@PGrivasMDPhD, @b_szabados
#BLADDR24  @OncoAlert @mirrorsmed

🔸️ctDNA+ post-RC detected in 52% of patients; 75% had recurrence &amp;lt;4 months. 🚨

🔸️Only 3% of…
nataliagandur's tweet image. 💫🌟Debate: The Role of ctDNA in Adjuvant MIBC Management
Moderator: Daniele Raggie 
SUPER PRESENTATION !!👏👏@PGrivasMDPhD, @b_szabados
#BLADDR24  @OncoAlert @mirrorsmed

🔸️ctDNA+ post-RC detected in 52% of patients; 75% had recurrence &amp;lt;4 months. 🚨

🔸️Only 3% of…


Cédric Lebâcle reposted

Day One of #BLADDR24 Presenter: Dr Cédric Lebâcle Debate: Are we ready to de-intensify treatment and surveillance in low-grade NMIBC? PRO and CON PRO: The debate on whether we are ready to de-intensify treatment and surveillance in low-grade non-muscle invasive bladder cancer…

OncoAlert's tweet image. Day One of #BLADDR24
Presenter: Dr Cédric Lebâcle 
Debate: Are we ready to de-intensify treatment and surveillance in low-grade NMIBC? 
PRO and CON

PRO:
The debate on whether we are ready to de-intensify treatment and surveillance in low-grade non-muscle invasive bladder cancer…
OncoAlert's tweet image. Day One of #BLADDR24
Presenter: Dr Cédric Lebâcle 
Debate: Are we ready to de-intensify treatment and surveillance in low-grade NMIBC? 
PRO and CON

PRO:
The debate on whether we are ready to de-intensify treatment and surveillance in low-grade non-muscle invasive bladder cancer…
OncoAlert's tweet image. Day One of #BLADDR24
Presenter: Dr Cédric Lebâcle 
Debate: Are we ready to de-intensify treatment and surveillance in low-grade NMIBC? 
PRO and CON

PRO:
The debate on whether we are ready to de-intensify treatment and surveillance in low-grade non-muscle invasive bladder cancer…
OncoAlert's tweet image. Day One of #BLADDR24
Presenter: Dr Cédric Lebâcle 
Debate: Are we ready to de-intensify treatment and surveillance in low-grade NMIBC? 
PRO and CON

PRO:
The debate on whether we are ready to de-intensify treatment and surveillance in low-grade non-muscle invasive bladder cancer…

Cédric Lebâcle reposted

Big AI discovered a new structural class of antibiotics! The last one took 38 years with multiple compounds effective vs methicillin-resistant Staph aureus, without toxicity. Article: nature.com/articles/s4158…


Cédric Lebâcle reposted

A big day for bladder ca patients @US_FDA. Massive team effort. Platinum based chemo superseded at last. EV/pembro will transform the lives of many pts with this difficult disease. Still lots to do but it’s a pretty good day and worth pausing for a moment. bit.ly/3GLntQn


Cédric Lebâcle reposted

Des applis de suivi de malades du cancer remboursées, un « tournant » dans la prise en charge whatsupdoc-lemag.fr/article/des-ap…

whatsupdoc_mag's tweet image. Des applis de suivi de malades du cancer remboursées, un « tournant » dans la prise en charge
whatsupdoc-lemag.fr/article/des-ap…

Cédric Lebâcle reposted

#CFU2023 session TVIM : analyse PMSI sur > 5000 cystectomies en France : la cystectomie par voie robot-assistée permet de diminuer la durée moyenne de séjour (-2 j) et le coût moyen du séjour (-1600e). Encore un argument supplémentaire pour privilégier cette voie d'abord !

PignotG's tweet image. #CFU2023 session TVIM : analyse PMSI sur &amp;gt; 5000 cystectomies en France : la cystectomie par voie robot-assistée permet de diminuer la durée moyenne de séjour (-2 j) et le coût moyen du séjour (-1600e). Encore un argument supplémentaire pour privilégier cette voie d&apos;abord !
PignotG's tweet image. #CFU2023 session TVIM : analyse PMSI sur &amp;gt; 5000 cystectomies en France : la cystectomie par voie robot-assistée permet de diminuer la durée moyenne de séjour (-2 j) et le coût moyen du séjour (-1600e). Encore un argument supplémentaire pour privilégier cette voie d&apos;abord !

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