CancerDepMap's profile picture. We construct systematic key datasets, analytical and visualization tools to accelerate precision cancer medicine #depmap
Our other account: @depmap.org

The Cancer Dependency Map

@CancerDepMap

We construct systematic key datasets, analytical and visualization tools to accelerate precision cancer medicine #depmap Our other account: @depmap.org

Przypięty

New DepMap Release! ⭐ 35 CRISPR screens ⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org) ⭐ First 281 WES -> WGS ⭐ New Resources page 📣 DepMap is now on dbGaP (phs003444.v1.p1) Read our release notes for more info!

CancerDepMap's tweet image. New DepMap Release!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org) 
⭐ First 281 WES -> WGS  
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1) 
Read our release notes for more info!

The Cancer Dependency Map podał dalej

In a new study, researchers from @MGHCancerCenter and colleagues' 'cell line atlas' provides a crucial resource for developing therapies for biliary tract cancer. The study was published in @CD_AACR. Read more: massgeneralbrigham.org/en/about/newsr… @getz_lab @DrFranVazquez

MGBResearchNews's tweet image. In a new study, researchers from @MGHCancerCenter and colleagues' 'cell line atlas' provides a crucial resource for developing therapies for biliary tract cancer. The study was published in @CD_AACR.

Read more: massgeneralbrigham.org/en/about/newsr… @getz_lab @DrFranVazquez…

The Cancer Dependency Map podał dalej

A new cell line atlas of biliary tract cancers uncovers new subtypes and potential drug targets for better treatment of these deadly diseases. Learn more: broad.io/DepMap-BTCs @MGBResearchNews @targetcancer

broadinstitute's tweet image. A new cell line atlas of biliary tract cancers uncovers new subtypes and potential drug targets for better treatment of these deadly diseases. Learn more: broad.io/DepMap-BTCs 

@MGBResearchNews @targetcancer

The Cancer Dependency Map podał dalej

theprismlab.org/white-papers/p… @CancerDepMap - PRISM screens can work with ADCs, bystander effects non-withstanding.

Muller_Lab's tweet image. theprismlab.org/white-papers/p…

@CancerDepMap - PRISM screens can work with ADCs, bystander effects non-withstanding.

The Cancer Dependency Map podał dalej

(1/3) Excited to share our latest work using @CancerDepMap to uncover a new synthetic lethality in two distinct patient populations! We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO nature.com/articles/s4158…

DrFranVazquez's tweet image. (1/3) Excited to share our latest work using  @CancerDepMap to uncover a new synthetic lethality in two distinct patient populations!

We found that SKI complex inactivation through two independent genomic alterations creates a dependency on PELO

nature.com/articles/s4158…

🚨Exciting New Synthetic Lethal Target from #depmap!

Scientists have discovered a genetic vulnerability — found in 5 percent of adult cancers — that could be a promising drug target. broad.io/PELO-News

broadinstitute's tweet image. Scientists have discovered a genetic vulnerability — found in 5 percent of adult cancers — that could be a promising drug target. broad.io/PELO-News


📢 Registration is now open for an exciting Gordon Conference on synthetic lethality organized by Ben Schwartz (GSK), Mathew Garnett (Sanger), and Francisca Vazquez (DepMap Director, Broad Institute) Highly recommended! Register here grc.org/synthetic-leth…

CancerDepMap's tweet image. 📢 Registration is now open for an exciting Gordon Conference on synthetic lethality organized by Ben Schwartz (GSK), Mathew Garnett (Sanger), and Francisca Vazquez (DepMap Director, Broad Institute)

Highly recommended! 

Register here
grc.org/synthetic-leth…

DepMap keeps growing—and so does the portal! To help navigate the portal, new in 24Q4 we’ve launched a new resource page 🚀! Check it out and share your feedback. depmap.org/portal/resourc…


Thank you for the suggestion!

Tip for further improvement: make HLA genotypes searchable for cell lines in DepMap. Would help a lot for TCR targeting therapeutics development



The Cancer Dependency Map podał dalej

New DepMap Release! ⭐ 35 CRISPR screens ⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org) ⭐ First 281 WES -> WGS ⭐ New Resources page 📣 DepMap is now on dbGaP (phs003444.v1.p1) Read our release notes for more info!

CancerDepMap's tweet image. New DepMap Release!
⭐ 35 CRISPR screens
⭐ NEW data from our Pediatric Dependencies Accelerator Program (learn more at PedDep.org) 
⭐ First 281 WES -> WGS  
⭐ New Resources page
📣 DepMap is now on dbGaP (phs003444.v1.p1) 
Read our release notes for more info!

The Cancer Dependency Map podał dalej

NEW content online! The present and future of the Cancer Dependency Map go.nature.com/4fiZ6sw

NatureRevCancer's tweet image. NEW content online! The present and future of the Cancer Dependency Map go.nature.com/4fiZ6sw

The Cancer Dependency Map podał dalej

Dear #DepMap portal users, we need your support for our NIH grant application funding the DepMap portal. If you like the portal, please consider answering this two-question survey so we can learn how you use it.

How do you use the DepMap Portal? 💻 As we enter the final year of our grant, we need your insights! Take this quick 2-question survey to help us understand what you like and what you'd like to see in the future. Your feedback is invaluable!  broad.io/dmp2024

CancerDepMap's tweet image. How do you use the DepMap Portal? 💻

As we enter the final year of our grant, we need your insights! Take this quick 2-question survey to help us understand what you like and what you'd like to see in the future. Your feedback is invaluable!  broad.io/dmp2024


How do you use the DepMap Portal? 💻 As we enter the final year of our grant, we need your insights! Take this quick 2-question survey to help us understand what you like and what you'd like to see in the future. Your feedback is invaluable!  broad.io/dmp2024

CancerDepMap's tweet image. How do you use the DepMap Portal? 💻

As we enter the final year of our grant, we need your insights! Take this quick 2-question survey to help us understand what you like and what you'd like to see in the future. Your feedback is invaluable!  broad.io/dmp2024

The Cancer Dependency Map podał dalej

We identified PHF6 as a critical #dependency for the survival of #SMARCB1-mutant cancers through #CRISPR screenings conducted in collaboration with @cancerdepmap.


🥳 The DepMap Portal Webinar is Today! 💻 Use the link below to join the Webinar at 12pm EST today. We look forward to seeing you there! broadinstitute.zoom.us/j/93295343885?…


📢 DepMap is hosting a webinar! Join members of the DepMap team on Thursday, Aug 1 starting at 12pm EST to learn more about the latest DepMap release and deep dive into Data Explorer 2.0. RSVP to let us know you're attending! bit.ly/45QLrFB


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