Sharon B. Cantor
@CantorLab
Professor studying DNA replication and role in cancer, chemoresistance, and developmental diseases
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Fascinating, congratulations Arnab-along with our recent MC paper, the role of the hereditary breast cancer genes in HR appears more and more indirect
Want to know how homologous recombination defects are caused upon loss of BRCA2? Check out our recent efforts in uncovering this phenomenon just out in Science! science.org/doi/10.1126/sc…
Australian Cell Cycle, DNA repair and Telomere meeting draft schedule is now online! Join us with 5 plenary speakers, 16 invited national speakers, 22 selected speakers, 61 poster presenters and lots and lots of fun science. Less than one month to go. australiancellcycle.org/draft-schedule/
Happy to share new work from my lab by co-authors Peng and Lee-when BRCA1 is absent, RAD51 is busy authors.elsevier.com/sd/article/S10…
Excited to share our latest research “DNA2 enables growth by restricting recombination-restarted replication” in @Nature defining DNA2’s essential function and elucidating links to primordial dwarfism and cancer. Thanks to the team and all collaborators! nature.com/articles/s4158…
nature.com
DNA2 enables growth by restricting recombination-restarted replication
Nature - DNA2 suppresses recombination-restarted replication and checkpoint activation at stalled forks, and its loss triggers recombination-dependent synthesis, checkpoint signalling and...
Exciting to see our protein binder design pipeline BindCraft published in its final form in @Nature ! This has been an amazing collaborative effort with Lennart, @csche11h, @sokrypton, @befcorreia and many other amazing lab members and collaborators. nature.com/articles/s4158…
LTRI is hiring! Excellent opportunity to start your own lab, work with amazing colleagues and access our top-notch scientific cores. All within the vibrant scientific core of downtown Toronto!
JOB ALERT 🚨 We are hiring TWO principal investigators in cell, molecular, systems, or chemical biology in Toronto, Canada. We provide a generous startup, fully funded salary and academic appointment at U of Toronto. nature.com/naturecareers/… Please repost!
Well deserved!
The #EMGS is pleased to announce the winner of the 2025 Samuel H. Wilson Award for Studies on DNA Repair, Dr. Mark Hedglin, PhD! Don't miss his presentation, "Rad6 Is Dynamically Accessible for Activation Within the Rad6(Rad18)2 Complex: Mechanistic Insights into a Ubiquitin…
Online Now: The DNA replication checkpoint limits Okazaki fragment accumulation to protect and restart stalled forks dlvr.it/TLZkmH
🛟Wow cyclic peptides are cool! Excited to share a new publication on "Potent Cyclic Peptide Inhibitors Disrupt the FANCM–RMI Interaction". Work led by @yuhenglau to which we contributed structures and ideas. The top hits mimic native MM2...but in reverse! pubs.acs.org/doi/10.1021/ac…
Now online! Centromeric DNA amplification triggered by viral proteins activates nuclear cGAS dlvr.it/TL7Js6
Three days, fresh data, & sparkly debates on how replication gaps drive cancer & disease. Grateful for every talk & discussion. Thank you for pushing science forward—next stop: great papers. Science moves fast when we move together! @CicciaAlberto @LabVincenzo
📢 For all DNA fiber enthusiasts! 🟥🟩 We are thrilled to announce the release of our long-awaited AI-based workflow for the automated and quantitative analysis of DNA fibers. It's an exciting step forward—check it out on bioRxiv! lnkd.in/dQWUPtsP
Our new preprint is now on bioRxiv! 📄 We introduce qAID, an AI-based workflow for automated analysis of DNA replication dynamics. Glad to have contributed a small part to this study.
Quantitative AI-based DNA fiber workflow to study replication stress biorxiv.org/content/10.110… #biorxiv_cellbio
Great opportunity to share your work!
Submit poster abstracts by 4/3, 11:59pm MST for the DNA Replication Gaps, Cancer, and Disease conference in Daejeon, South Korea. Join experts to explore DNA errors and cancer. Apply now: keysym.us/KSDNARep25 youtu.be/_aPIkDQg1rw #KSDNARep25 @CantorLab @CicciaAlberto
youtube.com
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KSQA: Dr. Kyungjae Myung (DNA Replication Gaps)
Submit poster abstracts by 4/3, 11:59pm MST for the DNA Replication Gaps, Cancer, and Disease conference in Daejeon, South Korea. Join experts to explore DNA errors and cancer. Apply now: keysym.us/KSDNARep25 youtu.be/_aPIkDQg1rw #KSDNARep25 @CantorLab @CicciaAlberto
youtube.com
YouTube
KSQA: Dr. Kyungjae Myung (DNA Replication Gaps)
NIH Grants Fueled $95 Billion In FY 2024 Economic Activity, Finds New Report forbes.com/sites/michaelt…
Gaps may be small but meeting will be big! come join us!youtube.com/watch?v=KgBUEc…
youtube.com
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DNA Replication Gaps, Cancer and Disease Meeting Promo
Thanks UMASS
Research by @UMassChan scientists Drs. Sharon Cantor (@CantorLab) and Jenna Whalen (@jenna_whal) provides a new explanation for how cancer-fighting drugs attack and destroy #BRCA1 and #BRCA2 tumor cells. 🧬 Learn more: bit.ly/4h33Pz9
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