CORtisol NETwork
@CortisolNetwork
CORNET: a consortium identifying genes influencing variation in cortisol, an intermediate phenotype in cardiometabolic and neuropsychological disease
This is a landmark for us @CortisolNetwork, confirming not only functional effect of high-cortisol variants but also causative association with CVD. Thanks to @TheBHF @wellcometrust @crayfish27 @BHFEdin_team @seanbankier nature.com/articles/s1003…
nature.com
Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid...
Journal of Human Genetics - Variation in the SERPINA6/SERPINA1 locus alters morning plasma cortisol, hepatic corticosteroid binding globulin expression, gene expression in peripheral tissues, and...
For ‘International Day of women and girls in Science’ #WomenInScience we took a photo of 5 of us who were in @EdMassSpecCore Core Facility @EdinUniCVS - technicians, research coordinators, post docs and core managers. @shazias51 @UoETechnicians @TechsCommit @CoreTechLifeSci
Many congratulations @ld_boyle for best oral in adrenal/cardiovascular #SfEBES2019 @EdinUniMetabol @BWalker1963
Characteristically forensic dissection of role and mechanisms of cortisol dysregulation in common cardiometabolic disease in CET Lecture at #SFEBES2019 by @BWalker1963. Experimental med tour de force!
Talking Stress today @IKEAEdinburgh with "Stress Busters" @MidlothSciFest #EdUniCvs Talk to our scientists about Cortisol in humans, horses &whales, Mass Spectrometry & try mini Chromatography @EdinburghCRF @WhaleWiseLive @EdMassSpecCore @ScienceUoE
More outcomes from the CORtisol NETwork GWAMA of cortisol...
More @EdSciFest fun with our 'Stress Busters' stand @NtlMuseumsScot today until 4.30pm. Talk to our researchers about measuring cortisol using Mass Spectrometry & try some liquid chromatography @ScienceUoE @WhaleWiseLive @EdinUniCVS @EdinburghCRF @GeosciencesEd #EdUniEdSciFiFest
Day 2 at @EdSciFest @NtlMuseumsScot. Ready to talk stress, mass spec, chromatography and blow sampling with @CortisolNetwork @EdMassSpecCore @EdinUniCVS #oceanharmony #whaleresearch
All ready with our 'Stress Busters' stand @NtlMuseumsScot 19th&20thApril for #MedicalFrontiers Talk to our researchers about cortisol, mass spectrometry, chromatography, health&whales @EdSciFest #EdUniEdSciFiFest @EdMassSpecCore @EdUniCVS @WhaleWiseLive @EdiburghCRF @ScienceUoE
Ready at Scottish Parliament today for @EdSciFest #EdUniEdSciFest @EdinUniCVS @EdinburghCRF with our ‘Stress Busters’ stand. Learn all about cortisol, chromatography and Mass Spectrometry @ruthmorgan31 @WhaleWiseLive
Large cross-sectional study showing positive correlation between stress and multimorbidity. Further work required to understand biological pathways and test causality maturitas.org/article/S0378-…
Medicines Regulators take note: we need routes for approval of interventions that hit several birds with one stone
Multiple chronic conditions: an emerging healthcare challenge: bit.ly/2UTJNNz Over the next 20 years the number of people with two or more chronic conditions will almost double to nearly 10 million. #ESRCBetterLives #ThisIsSocialScience @MODEMproject @OfficialNIHR
Important progress testing if pharmacological intervention on excess cortisol improves cognitive decline
First participant dosed in #XanaHES, a Ph 1 dose escalation safety study of #Xanamem in healthy elderly volunteers. “We are very excited to have reached yet another important milestone in the development of Xanamem …” said @billketelbey $ACW #alzheimers actinogen.com.au/wp-content/upl…
Hair cortisol associated with adiposity in large cohort scholar.google.co.uk/scholar?q=hair…
Als Professor der #Biopsychologie forscht Clemens #Kirschbaum unter anderem zum Thema Stress und gehört – auch dank seines großen Teams – zu den meistzitierten Forschern der #TUDresden. Mehr über den Sprecher des Bereiches @TUD_Science: unsere-uni-tud.de/testimonial/un… #unsereUNI
Intraindividual stability of hair cortisol concentrations ncbi.nlm.nih.gov/m/pubmed/21917…
More research using CORNET data biorxiv.org/content/biorxi…
Great to see CORNET data being used - Susceptibility to corticosteroid-induced adrenal suppression: a genome... sciencedirect.com/science/articl…
Summary GWAS data from our morning plasma cortisol GWAS are available to download from here - enjoy! datashare.is.ed.ac.uk/handle/10283/2…
Lovely paper by our colleagues in the Netherlands sciencedirect.com/science/articl…
United States Trendler
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