Scheinberg Lab
@DASLab_MSKCC
Developing cutting-edge therapeutics for cancer treatment @sloan_kettering. Tweets are from lab members, not from Dr. Scheinberg, unless signed -DAS.
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Congratulations to my husband, Dr. Bourne!! @TheBourneImmuno I'm so proud of you. It's an honor to be along for the ride.
I successfully defended my thesis. I am now Dr. Christopher Michael Bourne!
Congratulations to Dr. Bourne (@TheBourneImmuno) my younger big brother for an incredible thesis today! You’re truly an inspirational person in and out of the lab. A phenomenal scientist, dedicated DEI activist, and a monster of a cyclist! UPenn is incredibly lucky to have you!
A huge congratulations to @TheBourneImmuno on his recent thesis defense! You've done phenomenal work, and we look forward to your future success. You will be great missed!
Welcome to the lab and to Twitter @stephani0713! We are excited to see the awesome work you will do.
Hello Science Twitter! Please join me in welcoming @stephani0713 to the Sci Twitter sphere! She is a @TriIMDPhD student rotating in the @DASLab_MSKCC with me! She is also a soon-to-be @BlackinCancer member! 🌟🌟
Fantastic talk by @emma_reynaud99 wrapping up months of amazing work imaging CAR T cells in action diagnosing & treating cancers @MSKCancerCenter @LabKrebs @DASLab_MSKCC @SchuringaJan Larsonlab #theranostics
Congratulations to Dr. Heather Jones on her successful thesis defense today!! She delivered an outstanding presentation. Be on the lookout for her upcoming study on TCR cross-reactivity.
Congratulations to former fellow @MgKlatt on this groundbreaking publication! Using Mass Spec, we identify a novel target, NDC80, and target it with TCR mimic antibodies.
I am celebrating! My 11th paper from my postdoc-time at the amazing @DASLab_MSKCC Lab is now out @BloodJournal. I thank all fantastic collaborators for their support but especially @EurekaThera for their help and unlimited enthusiasm for TCRmimics. ashpublications.org/blood/article/… 1/2
ROCK STAR! Check out this article on our grad student @TheBourneImmuno on his recent Sawyers fellowship award! A Young Scientist Earns MSK Fellowship: Here’s When He Had His ‘Aha’ Moment mskcc.org/news/young-sci…
mskcc.org
A Young Scientist Earns MSK Fellowship: Here’s When He Had His ‘Aha’
Chris Bourne is the first recipient of the MERIT Sawyers Fellowship.
Excited to share my work from @DASLab_MSKCC lab out today in @nchembio where we develop CAR-T cells that produce small molecule drugs at the tumor site. This is an exciting step forward in the utilization of engineered cells for drug delivery! nature.com/articles/s4158…
Stay tuned! This is a massive collaboration across multiple labs and disciplines at @sloan_kettering @WeillCornellGS @WeillCornell !!
One critique of this platform that uses bacterial enzymes is that host immune responses will reject it. In my thesis work, I adapt this project in fully immunocompetent mouse models. We've had very promising efficacy results so far!
In our @DASLab_MSKCC paper we demonstrate that T cells can be engineered to release small molecule chemotherapies at the tumor site. We do this using bacterial enzymes. In the current paper, we use immunodeficient mouse models as a human proof of concept.
2.5 years of revision and over 5 years of collaborative work, CONGRATULATIONS to @TJJardinero , @DASLab_MSKCC and all others who contributed to this manuscript 🎉🎉🥳🥳. This novel platform will change adoptive T cell therapy. My thesis work will build on this. More info 👇🏾👇🏾👇🏾
Excited to share my work from @DASLab_MSKCC lab out today in @nchembio where we develop CAR-T cells that produce small molecule drugs at the tumor site. This is an exciting step forward in the utilization of engineered cells for drug delivery! nature.com/articles/s4158…
Congratulations @TJJardinero and our collaborators in the Tan lab for this awesome work! We show how adoptive T cell therapies like CAR T cells can be used to deliver small-molecule drugs to tumors. This is the first manuscript of many to come on this project.
Excited to share my work from @DASLab_MSKCC lab out today in @nchembio where we develop CAR-T cells that produce small molecule drugs at the tumor site. This is an exciting step forward in the utilization of engineered cells for drug delivery! nature.com/articles/s4158…
Congratulations to @PedroCSilberman on winning First Place at the @WeillCornellGS 3 minute thesis contest!
Congratulations to our student @TheBourneImmuno on receiving this transitional fellowship. Well deserved we are all very proud of you! 🎉🎉
It comes full circle! 🥳🥳I've been selected as the inaugural MSK MERIT Sawyers fellow! This provides 5 years of funding, 2 as a student, and 3 as a post doc!💸💰 Thank you to @MSKEducation and the Sawyers family for their commitment to diversity and my career growth. ❤🤩
Congratulations to @LeilaPeraro2 on publishing this story in @MolTherapy! We show that CAR T cells generate humoral immune responses in patients and we engineer them to secrete antibody-cleaving enzymes.
Dr. David Scheinberg's team (@DASLab_MSKCC) at @sloan_kettering and @EinsteinMed utilized the IgG protease “IdeS” to reprogram CAR T cells to defeat humoral #immune attacks ⚔️. bit.ly/36ejtWg
Congratulations to our former MD-PhD student @freddyeescorcia on receiving the Lasker Clinical Scholar award! This award provides up to 10 years funding from the NIH intramural program. Well deserved!
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