
Diffuse Bio
@diffuse_bio
We build AI models to design any protein, for any purpose.
We’ve just launched Minibinder Design on DiffuseSandbox.com! You can now design minibinders alongside scFvs and nanobodies. We’ve also upped our design limit. Read more on our blog post: diffuse.bio/new-feature-re…

New features available now on our protein GenAI platform DiffuseSandbox! scFv design with DSG2-mini is now live. We’ve also made open-source models RFAntibody + pMPNN available. diffusesandbox.com 1/

👋We’re excited to launch DSG2-mini, our newest AI protein design model, now available in DiffuseSandbox⏳🎁, our new app for protein binder design. Click through to design a protein yourself! diffusesandbox.com 1/
Foundation AI models in biology can result in a 7 orders of magnitude better hit rate for protein binders We are only beginning to see what can happen to biopharma in this next phase of AI
We prompted DSG-1 to design nanobody binders, a therapeutically relevant class of proteins. Remarkably, DSG-1 designs bound the target with a 3% hit rate, about seven orders of magnitude better than industry-standard discovery approaches. 4/

I’m excited to share some of our progress at @Diffuse_Bio today, about a year and a half into our journey! 1/
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