FraClaps's profile picture. MD, PhD candidate @UniLeiden | Consultant Urological Surgeon @iov_irccs | Fellow @NKI_nl | Former fellow Fundaciòn IVO | @SIU_Italia Communications Office

Francesco Claps

@FraClaps

MD, PhD candidate @UniLeiden | Consultant Urological Surgeon @iov_irccs | Fellow @NKI_nl | Former fellow Fundaciòn IVO | @SIU_Italia Communications Office

Francesco Claps reposted

📣 Corso di Perfezionamento UNIPA: “Diagnostica e Procedure Urologiche Guidate da Imaging” 🗓️ Marzo–Novembre 2026 | 400 ore | 16 CFU Focus su imaging in urologia (eco, TC, RM mp, PET/CT) + procedure guidate. ⏳ Scadenza: 03/02/2026 Info: [email protected]


Francesco Claps reposted

🎆📢First of 2026! Should we really give MMC maintenance in intermediate-risk #NMIBC, and for how long? #EAU guidelines recommend adj chemo but the optimal schedule remains unclear We tried to answer this clinically relevant gap.👇🧵 @Uroweb @urotoday @oncodaily @SpringerNature

RobertoContieri's tweet image. 🎆📢First of 2026!
Should we really give MMC maintenance in intermediate-risk #NMIBC, and for how long?
#EAU guidelines recommend adj chemo but the optimal schedule remains unclear

We tried to answer this clinically relevant gap.👇🧵
@Uroweb @urotoday @oncodaily @SpringerNature
RobertoContieri's tweet image. 🎆📢First of 2026!
Should we really give MMC maintenance in intermediate-risk #NMIBC, and for how long?
#EAU guidelines recommend adj chemo but the optimal schedule remains unclear

We tried to answer this clinically relevant gap.👇🧵
@Uroweb @urotoday @oncodaily @SpringerNature

Francesco Claps reposted

Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus THM: •average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer) •#LATP not cost-effective (QALY) But... •only 4m f/u so doesnt account for ⬆️ PCa diag #TRANSLATE_Trial eu-focus.europeanurology.com/article/S2405-…

TranslateTrial's tweet image. Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus

THM:
•average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer)
•#LATP not cost-effective (QALY)

But...
•only 4m f/u so doesnt account for ⬆️ PCa diag

 #TRANSLATE_Trial

eu-focus.europeanurology.com/article/S2405-…
TranslateTrial's tweet image. Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus

THM:
•average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer)
•#LATP not cost-effective (QALY)

But...
•only 4m f/u so doesnt account for ⬆️ PCa diag

 #TRANSLATE_Trial

eu-focus.europeanurology.com/article/S2405-…
TranslateTrial's tweet image. Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus

THM:
•average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer)
•#LATP not cost-effective (QALY)

But...
•only 4m f/u so doesnt account for ⬆️ PCa diag

 #TRANSLATE_Trial

eu-focus.europeanurology.com/article/S2405-…
TranslateTrial's tweet image. Pleased to publish #CostEffectiveness data #LATPvsTRUS in @EurUrolFocus

THM:
•average cost TRUS=£917; LATP=£1062 (∵ device cost/takes longer)
•#LATP not cost-effective (QALY)

But...
•only 4m f/u so doesnt account for ⬆️ PCa diag

 #TRANSLATE_Trial

eu-focus.europeanurology.com/article/S2405-…

Francesco Claps reposted

Need an update on the molecular pathology of bladder cancer? I am delighted to share a comprehensive review article by Dr. Antonio Lopez-Beltran and colleagues, published in the 2026 Annual Review Issue of Histopathology @Histo_Journal @daniel_berney 🔗 Article:…

LiangChengMD's tweet image. Need an update on the molecular pathology of bladder cancer? I am delighted to share a comprehensive review article by Dr. Antonio Lopez-Beltran and colleagues, published in the 2026 Annual Review Issue of Histopathology @Histo_Journal @daniel_berney
🔗 Article:…
LiangChengMD's tweet image. Need an update on the molecular pathology of bladder cancer? I am delighted to share a comprehensive review article by Dr. Antonio Lopez-Beltran and colleagues, published in the 2026 Annual Review Issue of Histopathology @Histo_Journal @daniel_berney
🔗 Article:…
LiangChengMD's tweet image. Need an update on the molecular pathology of bladder cancer? I am delighted to share a comprehensive review article by Dr. Antonio Lopez-Beltran and colleagues, published in the 2026 Annual Review Issue of Histopathology @Histo_Journal @daniel_berney
🔗 Article:…

Francesco Claps reposted

#mdpijcm 🩺#HighlyCitedPaper Citations 29🙌 The Prognostic Significance of Histological Subtypes in Patients with 𝐌𝐮𝐬𝐜𝐥𝐞-𝐈𝐧𝐯𝐚𝐬𝐢𝐯𝐞 𝐁𝐥𝐚𝐝𝐝𝐞𝐫 𝐂𝐚𝐧𝐜𝐞𝐫 👉mdpi.com/2885444 👥@GGiannarini @AlessiaCim @Nicp85Pavan @ongarluc_1991 @FraClaps @MediPharma_MDPI

JCM_MDPI's tweet image. #mdpijcm
🩺#HighlyCitedPaper
Citations 29🙌
The Prognostic Significance of Histological Subtypes in Patients with 𝐌𝐮𝐬𝐜𝐥𝐞-𝐈𝐧𝐯𝐚𝐬𝐢𝐯𝐞 𝐁𝐥𝐚𝐝𝐝𝐞𝐫 𝐂𝐚𝐧𝐜𝐞𝐫
👉mdpi.com/2885444
👥@GGiannarini @AlessiaCim @Nicp85Pavan @ongarluc_1991 @FraClaps
@MediPharma_MDPI

Francesco Claps reposted

BCG-unresponsive NMIBC trials feel confusing—and inconsistent EFS reporting is a big reason why We analyze the CIS+ cohorts of 4-FDA registration trials to provide interpretable EFS estimates 🧵👇 @Annals_Oncology @tompowles1 @JoshMeeks @wandering_gu doi.org/10.1016/j.anno…

monda_steven's tweet image. BCG-unresponsive NMIBC trials feel confusing—and inconsistent EFS reporting is a big reason why
We analyze the CIS+ cohorts of 4-FDA registration trials to provide interpretable EFS estimates
🧵👇
@Annals_Oncology 

@tompowles1 
@JoshMeeks 
@wandering_gu 

doi.org/10.1016/j.anno…

Francesco Claps reposted

“Low-grade Non–Muscle-Invasive Bladder Cancer: Molecular Landscape, Treatment Strategies, and Emerging Therapies” - just published in Nature Reviews Urology @NatRevUrol.  This State-of-the-Art review by Drs. Roger Li @UrogerliMD, Lexi Wen, and colleagues @philippespiess

LiangChengMD's tweet image. “Low-grade Non–Muscle-Invasive Bladder Cancer: Molecular Landscape, Treatment Strategies, and Emerging Therapies” - just published in Nature Reviews Urology @NatRevUrol.  This State-of-the-Art review by Drs. Roger Li @UrogerliMD, Lexi Wen, and colleagues @philippespiess…
LiangChengMD's tweet image. “Low-grade Non–Muscle-Invasive Bladder Cancer: Molecular Landscape, Treatment Strategies, and Emerging Therapies” - just published in Nature Reviews Urology @NatRevUrol.  This State-of-the-Art review by Drs. Roger Li @UrogerliMD, Lexi Wen, and colleagues @philippespiess…

Great brainstorming session today at #EMUC25 focused on advancing the most current insights in urothelial carcinoma research 🚀

FraClaps's tweet image. Great brainstorming session today at #EMUC25 focused on advancing the most current insights in urothelial carcinoma research 🚀

Francesco Claps reposted

One slide says it all! Terrific distillation by @MichvdHeijden of what to do in emerging pt populations in #bladdercancer, namely pts who received perioperative IO. Mirrors discussions we have been having in #kidneycancer. #ESMO25

montypal's tweet image. One slide says it all! Terrific distillation by @MichvdHeijden of what to do in emerging pt populations in #bladdercancer, namely pts who received perioperative IO. Mirrors discussions we have been having in #kidneycancer. #ESMO25

Francesco Claps reposted

⚡️ Cost-effectiveness of treatments for BCG-unresponsive CIS - analysis from our multicenter IBCG team. Five strategies modeled: 🔹Radical cystectomy (RC) 🔹Pembrolizumab 🔹Nadofaragene firadenovec 🔹Nogapendekin (NAI-BCG) 🔹Gemcitabine + Docetaxel ➡️Comprehensive…

UroDocAsh's tweet image. ⚡️ Cost-effectiveness of treatments for BCG-unresponsive CIS - analysis from our multicenter IBCG team. Five strategies modeled:
 🔹Radical cystectomy (RC)
 🔹Pembrolizumab
 🔹Nadofaragene firadenovec
 🔹Nogapendekin (NAI-BCG)
 🔹Gemcitabine + Docetaxel
 ➡️Comprehensive…

Francesco Claps reposted

In a trial of men with suspected prostate cancer, biparametric MRI, which excludes the gadolinium contrast sequence, was noninferior to multiparametric MRI for detecting clinically significant cases. 🧵 ja.ma/4nhCVqy

JAMA_current's tweet image. In a trial of men with suspected prostate cancer, biparametric MRI, which excludes the gadolinium contrast sequence, was noninferior to multiparametric MRI for detecting clinically significant cases. 🧵 

ja.ma/4nhCVqy

Francesco Claps reposted

On September 9, 2025, the Food and Drug Administration approved gemcitabine intravesical system (Inlexzo, Janssen Biotech, Inc.) for adults with BCG - unresponsive NMIBC with CIS with or without papillary tumors. Also known as TAR-200: this gemcitabine intravesical system is…

UroDocAsh's tweet image. On September 9, 2025, the Food and Drug Administration approved gemcitabine intravesical system (Inlexzo, Janssen Biotech, Inc.) for adults with BCG - unresponsive NMIBC with CIS with or without papillary tumors. 

Also known as TAR-200: this gemcitabine intravesical system is…

Francesco Claps reposted

JUST IN: IMvigor011 in muscle-invasive bladder cancer (MIBC) hits both DFS & OS with PD-L1 inhibitor Atezolizumab in ctDNA+ population. Major news for Precision Oncology in adjuvant Solid Cancers! @NateraGenetics @tompowles1 @Roche natera.com/company/news/i…

DrChoueiri's tweet image. JUST IN: IMvigor011 in muscle-invasive bladder cancer (MIBC) hits both DFS & OS with PD-L1 inhibitor Atezolizumab  in ctDNA+ population. Major news for Precision Oncology in adjuvant Solid Cancers!

@NateraGenetics @tompowles1 @Roche 

natera.com/company/news/i…

Francesco Claps reposted

The Prostate Imaging for Recurrence Reporting (PI-RR) system standardizes MRI performance and interpretation after prostatectomy or radiation therapy and is an essential reference for radiologists in standardizing reporting of recurrent prostate cancer. bit.ly/3JdTjtG

RadioGraphics's tweet image. The Prostate Imaging for Recurrence Reporting (PI-RR) system standardizes MRI performance and interpretation after prostatectomy or radiation therapy and is an essential reference for radiologists in standardizing reporting of recurrent prostate cancer. bit.ly/3JdTjtG

Francesco Claps reposted

Confirmation of the results of our RCT showing that PLND reduces metastasis without affecting BCR. @UrologyMSK @Uroweb @EUplatinum @JUrology @VickersBiostats #prostatecancer

TouijerKarim's tweet image. Confirmation of the results of our RCT showing that PLND reduces metastasis without affecting BCR. @UrologyMSK @Uroweb @EUplatinum @JUrology @VickersBiostats #prostatecancer
TouijerKarim's tweet image. Confirmation of the results of our RCT showing that PLND reduces metastasis without affecting BCR. @UrologyMSK @Uroweb @EUplatinum @JUrology @VickersBiostats #prostatecancer
TouijerKarim's tweet image. Confirmation of the results of our RCT showing that PLND reduces metastasis without affecting BCR. @UrologyMSK @Uroweb @EUplatinum @JUrology @VickersBiostats #prostatecancer

Francesco Claps reposted

Our team is in Sevilla for #UROonco25 📩 #NMIBC Deintensify LG Biomarkers to ⬇️ cystoscopy in HG #MIBC ctDNA is the future #UTUC Tailored patient care Go for kidney-sparing treatment @Uroweb @EAU_Uroonco @EAUYAUrology

EAU_YAUrotheli's tweet image. Our team is in Sevilla for #UROonco25 

📩

#NMIBC 
Deintensify LG
Biomarkers to ⬇️ cystoscopy in HG

#MIBC 
ctDNA is the future

#UTUC 
Tailored patient care
Go for kidney-sparing treatment 

@Uroweb @EAU_Uroonco @EAUYAUrology
EAU_YAUrotheli's tweet image. Our team is in Sevilla for #UROonco25 

📩

#NMIBC 
Deintensify LG
Biomarkers to ⬇️ cystoscopy in HG

#MIBC 
ctDNA is the future

#UTUC 
Tailored patient care
Go for kidney-sparing treatment 

@Uroweb @EAU_Uroonco @EAUYAUrology
EAU_YAUrotheli's tweet image. Our team is in Sevilla for #UROonco25 

📩

#NMIBC 
Deintensify LG
Biomarkers to ⬇️ cystoscopy in HG

#MIBC 
ctDNA is the future

#UTUC 
Tailored patient care
Go for kidney-sparing treatment 

@Uroweb @EAU_Uroonco @EAUYAUrology
EAU_YAUrotheli's tweet image. Our team is in Sevilla for #UROonco25 

📩

#NMIBC 
Deintensify LG
Biomarkers to ⬇️ cystoscopy in HG

#MIBC 
ctDNA is the future

#UTUC 
Tailored patient care
Go for kidney-sparing treatment 

@Uroweb @EAU_Uroonco @EAUYAUrology

Francesco Claps reposted

Excellent comprehensive review + metaanalysis on the diagnostic role of #PSMA Pet in #ProstateCancer ✅ High diagnostic value of PSMA PET, especially when combined with #MRI ✅ NPV indicates limitations to guide LND - not enough to omit biopsy @EUplatinum @oncodaily @elio_mazzone

brookmans76's tweet image. Excellent comprehensive review + metaanalysis on the diagnostic role of #PSMA Pet in #ProstateCancer
✅ High diagnostic value of PSMA PET, especially when combined with #MRI
✅ NPV indicates limitations to guide LND - not enough to omit biopsy
@EUplatinum @oncodaily @elio_mazzone
brookmans76's tweet image. Excellent comprehensive review + metaanalysis on the diagnostic role of #PSMA Pet in #ProstateCancer
✅ High diagnostic value of PSMA PET, especially when combined with #MRI
✅ NPV indicates limitations to guide LND - not enough to omit biopsy
@EUplatinum @oncodaily @elio_mazzone
brookmans76's tweet image. Excellent comprehensive review + metaanalysis on the diagnostic role of #PSMA Pet in #ProstateCancer
✅ High diagnostic value of PSMA PET, especially when combined with #MRI
✅ NPV indicates limitations to guide LND - not enough to omit biopsy
@EUplatinum @oncodaily @elio_mazzone

🚨New in @EUPlatinum! 📌 PSMA PET for Prostate Cancer Diagnosis & Staging by @elio_mazzone et al 🧠 This comprehensive meta-analysis confirms the high diagnostic value of PSMA PET—especially when combined with MRI—but reminds us it’s not enough to skip biopsy or lymph node…

EUplatinum's tweet image. 🚨New in @EUPlatinum!
📌 PSMA PET for Prostate Cancer Diagnosis & Staging by @elio_mazzone et al
🧠 This comprehensive meta-analysis confirms the high diagnostic value of PSMA PET—especially when combined with MRI—but reminds us it’s not enough to skip biopsy or lymph node…


Francesco Claps reposted

A 🧵 on our recent study on surveillance for IR-NMIBC @EurUrolOncol authors.elsevier.com/c/1l7pU_wtP00L… There is limited evidence on follow-up for IR-NMIBC. We used data from >2000 primary Ta–T1 NMIBC to stratify IR-NMIBC by recurrence risk and propose a risk-adapted follow-up approach.

RobertoContieri's tweet image. A 🧵 on our recent study on surveillance for IR-NMIBC @EurUrolOncol authors.elsevier.com/c/1l7pU_wtP00L…
There is limited evidence on follow-up for IR-NMIBC. 
We used  data from >2000 primary Ta–T1 NMIBC to stratify IR-NMIBC by recurrence risk and propose a risk-adapted follow-up approach.

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