Don-Marc Franchini
@FranchiniDM
Research Scientist @ CRCT-IUCT Toulouse | T lymphocytes, RNP granules, immune checkpoints, small molecule drug discovery.
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P-bodies; sites of excess RNA accumulation, or actors in gene regulation? We tackle this long-held question by looking at the RNA content in p-bodies across the cell cycle. Feedback much appreciated. authors.elsevier.com/c/1jtTs3vVUPRn…
Please RT. Are you interested in performing your master thesis with us @imbmainz? We have exciting projects on nuclear myosin VI in genome stability. Details below imb.de/fileadmin/imb/… If interested please apply via the link or contact me directly.
Excited to see our story showing that the #stressresponse regulator #HSF1 modulates NK cell anti-tumour immunity out in @NatureCellBio. Thanks to fantastic work with @nkourtis @iannisaifantis1 and team @nyulangone 🧵👇 nature.com/articles/s4155…
1/Excited to share our latest study showing that RNA sequestration in P-bodies sustains myeloid leukemia - now out in @NatureCellBio! nature.com/articles/s4155…. 🧵 below:
I am very proud of the superstar postdoc @Yang_Haojun_01, who discovered how to translation control underlying fasting and ketogenic diet in health and cancer. nature.com/articles/s4158…
Excited to announce our latest publication from the amazing Ying Xie in @MolecularCell We find that stress granules and P-bodies fluidize the cytoplasm in response to diverse stresses. Tweetorial soon! cell.com/molecular-cell…
@Xisca_Aguilo and me have curated a collection on translational regulation and #cancer, out now in @NAR_Cancer_EIC 🔗academic.oup.com/narcancer/page… Contributions from @LorenzoMontana4 @s_millevoi @GebauerLab @johnprensner @Denicourt_Lab @Sblancolab @FallerLab and others #RNA #RBP
If you are interested in NK cells and cancer immunotherapy, two positions are open in @EricVivier1's lab at @CIML_Immunology. For more info 👇
I’m Thrilled to share the latest study of the team #NoLymIT @crctoncopole by @PabloCerapio in @pathsoc revealing heterogeneity of splenic marginal zone lymphoma by single cell/spatial analyses. …thsocjournals.onlinelibrary.wiley.com/doi/10.1002/pa…
Delighted to share this review published in @TrendsMolecMed I have been involved in with a long-time collaborating team @TeamRNAReg @crctoncopole PD-L1 at the crossroad between RNA metabolism and immunosuppression sciencedirect.com/science/articl…
I am recruiting a talented and dedicated postdoc! tRNA epitranscriptomics-immunoOncology Please apply @ [email protected] giga.uliege.be/upload/docs/ap… @Translacore @EACRnews @epitran @TSI_lab_LIH @ArnBlomme
Delighted to share our article on the Discovery of SOCS7 as a versatile E3 ligase for protein-based degraders published @iScience_CP. Thanks to the authors @AnaisCornebois @MarieSorbara @Margot_Cristol @CordelierPierre and our collaborators from @sanofi! cell.com/iscience/fullt…
Our recent work (led by @sammykeyport) on evolution of biomolecular condensation is now highlighted as a featured article (and is open access) 🔬 nature.com/collections/bb… nature.com/articles/s4146…
***PhD Opportunity*** "(Inter)Facing mechanotransduction-related aspects of brain tumour cell metastasis and therapeutic resistance" If 1) these key words raise your curiosity, 2) you could imagine to live in Glasgow🏴 and 3) work at the @StrathBiomedEng , please contact me😊!
🚨Postdoc position announcement!!! Please share and RT.🚨 The Scipioni Lab is seeking a highly motivated and skilled postdoctoral researcher to work on cutting-edge projects involving the design, development, and implementation of advanced microscopes (see below) 1/4
Online Now: Time-resolved profiling of RNA binding proteins throughout the mRNA life cycle dlvr.it/T5GfWv
Finally, out! DDX6 modulates P-body and stress granule assembly, composition, and docking: doi.org/10.1083/jcb.20… We show that the P-body protein and RNA helicase DDX6 regulates stress granules by limiting RNA and RNA binding protein partitioning.
Make sure not to miss this workshop on RNA and cancer research organized by students together with @FabienneMEGGET2 of the RNA focus research axis of the @crctoncopole. Great science is guaranteed!
Curious about #RNA & #cancer research? Don't miss the 𝟐𝐧𝐝 𝐑𝐍𝐀&𝐜𝐚𝐧𝐜𝐞𝐫 𝐰𝐨𝐫𝐤𝐬𝐡𝐨𝐩 at the Cancer Research Center of Toulouse on May 23. Present your research next to international keynote speakers and industry sponsors. Submit here: rnacancer.sciencesconf.org.
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