GiusToLab's profile picture. Assistant Professor of Neurology @ColumbiaMed #PopulationGenetics #Epidemiology #Neuroscience #Alzheimer #ENDALZ  🏳️‍🌈

GiusTo Lab

@GiusToLab

Assistant Professor of Neurology @ColumbiaMed #PopulationGenetics #Epidemiology #Neuroscience #Alzheimer #ENDALZ 🏳️‍🌈

Pinned

𝘼𝙋𝙊𝙀-ε4 and ε2 effect in Alzheimer's Disease varies across populations! Check our findings in the largest collection of Hispanics/Latinos now published in @alzdemjournals 📰 alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

GiusToLab's tweet image. 𝘼𝙋𝙊𝙀-ε4 and ε2 effect in Alzheimer's Disease varies across populations!
Check our findings in the largest collection of Hispanics/Latinos now published in @alzdemjournals 

📰 alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

Check out our lab's latest software! 𝗦𝗔𝗚𝗔 runs 𝗴𝗲𝗻𝗼𝗺𝗲𝘄𝗶𝗱𝗲 𝗮𝘀𝘀𝗼𝗰𝗶𝗮𝘁𝗶𝗼𝗻 𝗮𝗻𝗮𝗹𝘆𝘀𝗲𝘀 with a simple one-line command! Anyone can access complex genetic analyses 🙌 [developed by the talented Basilio Cieza] 📌biorxiv.org/content/10.110…


GiusTo Lab reposted

Africa is making history with its first large-scale Alzheimer’s datasets 🧠✨ Read more in the link!

HIHGatUM's tweet image. Africa is making history with its first large-scale Alzheimer’s datasets 🧠✨ Read more in the link!
HIHGatUM's tweet image. Africa is making history with its first large-scale Alzheimer’s datasets 🧠✨ Read more in the link!
HIHGatUM's tweet image. Africa is making history with its first large-scale Alzheimer’s datasets 🧠✨ Read more in the link!
HIHGatUM's tweet image. Africa is making history with its first large-scale Alzheimer’s datasets 🧠✨ Read more in the link!

GiusTo Lab reposted

Presenting my preliminary results of APOE e4 and Ptau 217 over cognition in quechua and aymara population from GAPP study at #AAIC25 in Toronto. Thanks to @GiusToLab, @NiltonCustodio8 @marciosotoanari

ClaudiaRivFer's tweet image. Presenting my preliminary results of APOE e4 and Ptau 217 over cognition in quechua and aymara population from GAPP study at #AAIC25 in Toronto. Thanks to @GiusToLab, @NiltonCustodio8 @marciosotoanari

GiusTo Lab reposted

How does APOE status impact AD risk in Hispanics/Latinos? Research in A&D report APOE ε4 shows a heterogeneous effect on ADRD risk across Hispanic/Latino populations, with the strongest associations in Peruvians/Bolivians #AlzResearch alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

alzdemjournals's tweet image. How does APOE status impact AD risk in Hispanics/Latinos?

Research in A&D report APOE ε4 shows a heterogeneous effect on ADRD risk across Hispanic/Latino populations, with the strongest associations in Peruvians/Bolivians #AlzResearch

alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

GiusTo Lab reposted

What does heritability mean as measured multiple ways and what does it mean for our understanding of Alzheimer's? Alzheimer disease is (sometimes) highly heritable: Drivers of variation in heritability estimates for binary traits, a systematic review medrxiv.org/content/10.110…


Took a minute (4+ years😅), but we made it! We studied the heterogeneity of APOE and Alzheimer's Disease risk using the largest collection of Hispanic/Latino studies - an amazing collective effort🎉 alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

GiusToLab's tweet image. Took a minute (4+ years😅), but we made it!

We studied the heterogeneity of APOE and Alzheimer's Disease risk using the largest collection of Hispanic/Latino studies - an amazing collective effort🎉 

alz-journals.onlinelibrary.wiley.com/doi/10.1002/al…

v nice thread

I wrote about how population stratification in genetic analyses led to a decade of false findings and almost certainly continues to bias emerging results. But we are starting to have statistical tools to sniff it out. A 🧵:

SashaGusevPosts's tweet image. I wrote about how population stratification in genetic analyses led to a decade of false findings and almost certainly continues to bias emerging results. But we are starting to have statistical tools to sniff it out. A 🧵:


Congrats to our star clinical coordinator Jennifer Ortega Morales - she matched yesterday for the Internal Medicine Residency Program! #proudPI

GiusToLab's tweet image. Congrats to our star clinical coordinator Jennifer Ortega Morales - she matched yesterday for the Internal Medicine Residency Program!
#proudPI

Closing day at the Brain Ageing and Dementia in LMICs 2024 conference in Nairobi, Kenya 🇰🇪 Dr. @pericakvance taking the stage to present our @NIHAging funded DAWN study for which we have been recruiting thousands of seniors in US and Africa thedawnstudy.com

GiusToLab's tweet image. Closing day at the Brain Ageing and Dementia in LMICs 2024 conference in Nairobi, Kenya 🇰🇪 

Dr. @pericakvance taking the stage to present our @NIHAging funded DAWN study for which we have been recruiting thousands of seniors in US and Africa

thedawnstudy.com

see you in Vienna! #ENDALZ 🗓️program here: adpd.kenes.com/scientific-pro…

GiusToLab's tweet image. see you in Vienna! #ENDALZ

🗓️program here: adpd.kenes.com/scientific-pro…

We now have a zebrafish model 🐟 to better dissect the genetics underpinning Fetal Alcohol Spectrum Disorders #FASD - thanks to @CaKizil @gaattagca @NIAAAnews preprint here 👇🏼 biorxiv.org/content/10.110…

A new project from our lab! Fascinating #admixture study on this underrepresented South African population and the risk profile for Fetal alcohol spectrum disorders #FASD. 1% to 5% of U.S. first graders have FASD! @NIAAAnews medrxiv.org/content/10.110…

GiusToLab's tweet image. A new project from our lab!

Fascinating #admixture study on this underrepresented South African population and the risk profile for Fetal alcohol spectrum disorders #FASD.
1% to 5% of U.S. first graders have FASD! @NIAAAnews 

medrxiv.org/content/10.110…


Check out our poster #338 showing the performance of ptau-217 for #Alzheimer in a large South American cohort #AAIC2024 #biomarkers

GiusToLab's tweet image. Check out our poster #338 showing the performance of ptau-217 for #Alzheimer  in a large South American cohort

#AAIC2024 
#biomarkers

Living our best life with AAIC boxed lunch 😂

GiusToLab's tweet image. Living our best life with AAIC boxed lunch 😂

Join us today at 4:15 pm EST! #AAIC2024

GiusToLab's tweet image. Join us today at 4:15 pm EST!
#AAIC2024

GiusTo Lab reposted

1/ Even in the era of single-cell RNAseq, bulk-RNAseq data are still very valuable. 10 tools/papers related to bulk-RNAseq deconvolution.🧵


I'm chairing the "𝗚𝗲𝗻𝗼𝗺𝗶𝗰𝘀 𝗼𝗳 𝗔𝗗𝗥𝗗 𝗶𝗻 𝗱𝗶𝘃𝗲𝗿𝘀𝗲 𝗽𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀" session at the upcoming #AAIC2024 in Philly ! Come visit us! 📅Monday, July 29th ⏲️4:15-5:45pm EST ℹ️ aaic.alz.org/program/scient…

GiusToLab's tweet image. I'm chairing the "𝗚𝗲𝗻𝗼𝗺𝗶𝗰𝘀 𝗼𝗳 𝗔𝗗𝗥𝗗 𝗶𝗻 𝗱𝗶𝘃𝗲𝗿𝘀𝗲 𝗽𝗼𝗽𝘂𝗹𝗮𝘁𝗶𝗼𝗻𝘀" session at the upcoming #AAIC2024 in Philly ! Come visit us! 

📅Monday, July 29th
⏲️4:15-5:45pm EST
  ℹ️ aaic.alz.org/program/scient…

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