Nathan Constantine-Cooke
@IBDNathan
PostDoc health data scientist in @charlie_lees' group @UoE_CGEM and @CataVallejosM's group @mrc_hgu. Modelling biomarkers in IBD.
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Happy to announce our #IBD research, in which we use faecal calprotectin over time to characterise Crohn's disease heterogeneity, is now available as an article in press with @AGA_CGH! (Open access and proofed versions to follow at a later date) cghjournal.org/article/S1542-…
The code for last week's PREdiCCt Study paper is now publicly available. github.com/nathansam/pred…
What can (and cannot) predict flares in people with #IBD in remission❓ 💡New insights from the PREdiCCt Study from @IBDNathan, @Bealoquebea, @charlie_lees & colleagues after following 2,629 people 🇬🇧 in self-reported remission for 4 years: ✅ Feeling well is not the same as…
We'll be shining a light on the PREdiCCt study in a forthcoming podcast episode! @IBDNathan, one of the study authors (and an #IBD patient himself, to boot), will be joining Nigel and me later this week to discuss the results and what they mean for those of us with Crohn's & UC.
A study of this scale only happens because of the people behind the numbers. As we share the first results from PREdiCCt in @Gut_BMJ, it is vital to acknowledge the immense human effort that made this possible over the last decade. Lisa Derr has been the brilliant engine room of…
What really defines an IBD flare? In the PREdiCCt study - published today in Gut - we explored the crucial disconnect between how a patient feels and what their biology says. Nik Plevris, consultant gastroenterologist at the Edinburgh IBD unit, dives into our findings on…
One of the most common questions in any IBD clinic is: What should I eat? Beatriz Gros, consultant gastroenterologist and researcher, shares the landmark dietary results from the PREdiCCt study, now published in Gut. We studied the habitual diets of over 1,000 patients in…
The first PREdiCCt study paper is published tomorrow in #Gut! Watch our video on the study design with videos also forthcoming from Nikolas Plevris and Beatriz Gros describing key results.
Why do people with Crohn's and Colitis flare? This is the fundamental question we set out to answer when we started the PREdiCCt study in 2016. On Tuesday, the first major results will be published in @Gut_BMJ We wanted to look beyond just the clinical data. We focused on…
Why do people with Crohn's and Colitis flare? This is the fundamental question we set out to answer when we started the PREdiCCt study in 2016. On Tuesday, the first major results will be published in @Gut_BMJ We wanted to look beyond just the clinical data. We focused on…
Nice to see an UpsetR plot in the wild cran.rstudio.com/web/packages/U…
⚠️ ❗ Real-world effectiveness of risankizumab in Crohn’s disease: a pan UK retrospective cohort study 🚨 🚨 👫 763 participants with CD 💉 Treatment persistence at 6 and 12 months was 95.4% and 89.2%, respectively ✅ Rates of clinical, CRP and FCAL remission were 52%…
🚨We’ve been on a roll with papers📄! Read about our pan-UK RWE study of risa in CD (across 25 health boards!). Huge thanks to the HCPs and 763 people living with IBD that contributed to this study.
⚠️ ❗ Real-world effectiveness of risankizumab in Crohn’s disease: a pan UK retrospective cohort study 🚨 🚨 👫 763 participants with CD 💉 Treatment persistence at 6 and 12 months was 95.4% and 89.2%, respectively ✅ Rates of clinical, CRP and FCAL remission were 52%…
Delighted to see this out. Many thanks to @AlexElford3 and @PlevrisN for driving this project, and for all contributing sites across the UK. It is a big cohort (n=763 patients treated with risa).
⚠️ ❗ Real-world effectiveness of risankizumab in Crohn’s disease: a pan UK retrospective cohort study 🚨 🚨 👫 763 participants with CD 💉 Treatment persistence at 6 and 12 months was 95.4% and 89.2%, respectively ✅ Rates of clinical, CRP and FCAL remission were 52%…
⏰ Final call — applications close Sunday Advanced Clinical Fellow (IBD Gastroenterology) — Edinburgh If you're an advanced gastroenterology trainee thinking about your next move, this IBD-focused fellowship at the Western General Hospital might be exactly what you're looking…
Today we report a 5-year effort led by @IBDNathan in collaboration with @PREDICTIBD in Denmark, to map inflammatory trajectories in IBD using calpro and CRP. Using latent class mixed models, we clustered patients by similar longitudinal biomarker profiles and identified eight FC…
Turbocharge your GI career in 2026! 🚀 The Edinburgh IBD Unit is hiring an Advanced Clinical Fellow. 🔹 World-leading center 🔹 Cutting-edge translational research 🔹 Advanced training in IBD + Data Science Follow in the footsteps of alumni like Nik Plevris & Beatriz Gros.…
Skittles and dinner @TheSheepHeid for the team Christmas dinner last night. Totally fabulous evening in Scotland’s oldest pub - to celebrate a fantastic year and thank everyone for their hard work.
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