Today’s Insights IBD
@IBDinsights
#IBD patient advocate • #bileacids • strategic consultant • innovative solutions in healthcare • author of How I feel with Crohn’s/UC (pediatric resource)
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The first journals have arrived. How I Feel With Crohn’s/Ulcerative Colitis will be available next week as a free download. This comprehensive & compassionate resource is designed to inspire, comfort, and empower children living with #IBD.
There's a medical condition that affects many in the UK. Few HCPs seem to know about it. Often dismissed as #IBS. Can take years to get diagnosed - #bileacidmalabsorption. Latest episode of our #IBD Patients' podcast has been the fastest downloaded so far podcasts.apple.com/us/podcast/15-…
🌍 Why do the Faroe Islands have the highest #IBD incidence worldwide – 1 in 50 people? Prof. Johan Burisch 🇩🇰 shares insights on rising rates, local “hotspots,” and continued research collaboration with Faroese doctors. 📽️ Watch: youtu.be/8Wf7aouejW4 #miGutHealth #HorizonEU
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YouTube
miGut - Health Project | Interview with Johan Burisch
8. We found 116 genes associated with Crohn’s disease show differential expression in equivalent colon tissue cell types sampled from healthy and diseased individuals in an external dataset. This includes ZBTB38, a candidate susceptibility gene implicated in recent GWAS.
Important interview highlighting the pressing need for novel and innovative approaches in IBD research. #IBD #crohnsdisease
“Why do we need new targets for Crohn’s therapies?“ In this 1 Minute Inside IBD, the Promakhos Therapeutics team explains: ✨ Current drugs have hit their ceiling of efficacy ✨ There’s an upstream problem driving disease ✨ The real goal is restoring the innate immune system…
This study suggests that a diet with high TAC may help prevent the development of #IBD, particularly in individuals at high genetic risk of IBD and in mutation carriers of rs4880 in SOD2 ➡️ ow.ly/wyTk50WByvO
🧐 Curious about IBD research? On #AboutIBDPodcast, I talk with @propelacure president & CEO, Angela Clark. Propel a Cure funds research into the causes of #Crohns. Listen in any podcast app, see a video on YouTube, or use my website to choose either: bit.ly/AIBD180
Calling for any people with Crohn’s disease- could you please complete the following survey (less than 5 mins) to help me progress some research forwards 🙏🏽 forms.gle/kdUSc2MCad82dr…
Pleased to have been able to work with Chris Bannon and colleagues in Cambridge and elsewhere to help show a role for INL5 Discovery of role of gut hormone in chronic diarrhoea could aid development of new tests and treatments cam.ac.uk/research/news/…
Absolutely agree. Thank you for pointing this out. I was waiting for the #bileacids comments in this thread. Would include dietary interventions as well. While current bile acid binders may not work sufficiently for all patients, the combination of ileal disease and the role of…
Suggests that a trial of bile acid binders should be part of the run-in to clinical trials in CD (ileal disease or prior resection). This is part of what makes CD so noisy (along with fibrosis, obstruction, penetrating disease, etc)
To all #bileacids enthusiasts: this is an interesting post/newsletter!
1/2 There is a drug called ursodeoxycholic acid that dissolves gallstones. Urso means “bear” in Latin. Why is it called that? Why does our OSOPOLAR (POLAR BEAR) clinical trial have that name?
Happy to share our study on #EEN in #CrohnsDisease: ✅Early assessment by week 3 predicts remission at end of therapy ✅Adherence = better outcomes ✅Frequent dietitian review boosts completion rates 💡 Dietetic support is crucial to successful EEN therapy onlinelibrary.wiley.com/doi/10.1002/jg…
Another great read on #bileacids metabolism. “T6SS-mediated antagonism regulates the structure and composition of gut microbiota, affecting the entire gut metabolome, particularly the bile acids metabolism, subsequently reducing inflammation response in the intestine and…
#GUTOnline paper by Li et al on "Commensal Bacteroides T6SS alleviate GI-aGVHD via mediating gut microbiota composition and bile acids metabolism" via bit.ly/4dODN2q #GutMicrobiota
A shout-out to @UBC researchers who are refining a targeted drug delivery system -- GlycoCaging -- that could avert the systemic side effects of steroids and other #IBD medications. globalnews.ca/video/11160379… #crohns #crohnsdisease #ulcerativecolitis
globalnews.ca
UBC researchers claim breakthrough in inflammatory bowel disease |...
We are excited to present our recent virtual discussion with Dr. @JoanaTo62523004, who brings us up to date on the latest in #IBD prediction and prevention! She shares with us the remarkable headway that researchers are making in predicting disease risk years before onset, as…
There's still time to submit for this year's @NASPGHAN foundation grants for 2025! 💸With grants available at all career levels and interests, spanning from Carbohydrate malabsorption to Liver disease!!! Grant submissions due on 7/1!! tinyurl.com/jcu2shwk
🔬A very interesting research poster presented at the #ECCO2025 conference in Berlin this year by Van der Kruk et al. highlighted microbially conjugated bile acids (MCBAs) as potential biomarkers for dietary therapy outcomes in pediatric patients with Crohn’s disease. ❗️In…
We need your help to gain a greater perspective on this topic, please help us with your insights This would be much appreciated
🚨Just7⃣days left! 🤔How is AI transforming #IBD care🌍? Share your insights, 5–10 min📰 🩺GIs, surgeons, nurses, dietitians➡️ involved in IBD care! 📅 May 3⃣1⃣ @AmerGastroAssn @AmCollegeGastro @ELC_APAGE @ScrubsNHeels @JosephHabibi_MD @Bealoquebea 🔗redcap.link/ga8czjlu
Thanks to your support, THREE Propel a Cure sponsored research projects are challenging the status quo & offering real hope for better treatments—and a cure—for #crohnsdisease. On Propel a Cure Giving Day and #WorldIBDDay, your gift fuels the kind of bold, outside-the-box…
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