JAMA Oncology
@JAMAOnc
JAMA Oncology is a member of the JAMA Network, a consortium of peer-reviewed, general medical and specialty publications.
Potrebbero piacerti
In active surveillance for #ProstateCancer, #MRI was most reliable for ruling out significant cancer in low PSA density cases but failed to achieve sufficient accuracy in broader populations. ja.ma/4r12e2O
Meta-analysis: Among patients with intermediate-, high-, or very high-risk prostate cancer, the ideal duration of ADT with radiotherapy demonstrated nonlinear benefits, with diminished gains after 12 months and variation in benefit by risk group. ja.ma/4oOZmVc
💬 Viewpoint: #Medicaid cuts and work requirements in the 2025 budget law risk reduced access to cancer prevention, delayed diagnoses, later-stage disease at presentation, and caused worse cancer outcomes. ja.ma/3JJX22H
💬 Viewpoint: Trust in medicine has declined due to the #COVID19 pandemic and abundant online health information, highlighting the need for transparent, patient-focused communication. ja.ma/4hWen4W
Among patients with advanced urothelial cancer, upfront enfortumab vedotin dose reduction was linked to a 50% reduction in treatment interruption risk but did not compromise overall survival. ja.ma/47L9DdG
💬 Viewpoint: #OvarianCancer's unique attributes complicate early detection, necessitating personalized risk-based strategies for better prevention and outcomes. ja.ma/3Jwfzzu
Cross-disciplinary international position statement summarizes the current understanding of CV toxic effects associated with ICI therapy, including strategies for diagnosis, treatment, and potential rechallenge and an outline of relevant knowledge gaps. ja.ma/47FVdNs
Among women under 50, those with the highest ultraprocessed food intake had 45% higher odds of early-onset colorectal conventional adenomas versus those with the lowest intake; no significant association was seen for serrated lesions. ja.ma/4r2lqxo
In a nonrandomized phase 2 trial of adults with advanced dMMR/MSI-H noncolorectal cancers, combined nivolumab/ipilimumab showed an objective response rate of 63% and 6-month progression-free survival rate of 71%. ja.ma/4i68zWQ
💬 Viewpoint: Addressing food insecurity, particularly among #cancer patients, requires systemic policy changes that prioritize sustainable funding and support for large-scale food assistance programs. ja.ma/4qRuiWy
💬 Viewpoint: Oncology is shifting toward personalized, less aggressive treatments for "good-risk" metastatic prostate cancer and similar tumors, prioritizing efficacy and quality of life over overtreatment. ja.ma/43g6Yrb
A 78-year-old man with a history of nonmelanoma skin cancers presented with left-sided upper and lower facial weakness. What is your diagnosis? ja.ma/49DWPs8
The JAMA Network invites research submissions on #AI in clinical settings, prioritizing rigorous methodologies and validation for informed medical practice. 🔗 See the full submission criteria: ja.ma/4hhwv92
Viewpoint: GLP-1 receptor agonists induce weight loss but may lead to pronounced muscle mass reduction, raising concerns for patients with cancer at risk of frailty and decreased physical function. ja.ma/49LbiT8
Rare pathogenic variants in 16 #cancer predisposition genes were linked to both single and multiple cancer diagnoses, suggesting multigene panel testing could be beneficial. ja.ma/4hMGweD
Semaglutide and tirzepatide prescriptions for obesity have increased among patients with preexisting cancer, with notable variation by cancer type and absence of cancer-specific guidelines. ja.ma/3JzvqNE
AI technologies hold potential to enhance acute myeloid leukemia management by improving risk stratification, early detection, and treatment optimization through integration of clinical, morphological, and genetic data. ja.ma/3Xk9au8
Older age in unrelated donors linked to lower survival in allogeneic hematopoietic cell transplant with conventional calcineurin inhibitor-based graft-vs-host disease prophylaxis, but this association is mitigated with posttransplant cyclophosphamide. ja.ma/4ornu09
Consistent moderate physical activity—about 17 metabolic equivalent task-hours/week over 3 decades—was associated with optimally reduced risk of digestive system cancers in a large cohort study. ja.ma/49pLUlS
While the use of fertility-preserving #HormonalTherapy for early-stage endometrial #cancer has increased, survival outcomes are comparable to #hysterectomy in patients under 40. ja.ma/3LdSq5i
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