Joseph A. Miccio, MD
@JAMRadOnc
Father, husband, and radiation oncologist | Assistant Professor @PennStateHershey | former resident @yaleradonc | Pitt Panther fan (H2P)
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🎗️October is Breast Cancer Awareness Month. Radiation treatment is more than a therapy - it's a step toward healing and renewed hope. Every beam is aimed at a future free from cancer. To everyone walking this path; your strength inspires us all. 💗@PennStHershey
📢 Excited to welcome @VinitaTakiar, the new Chair of the Department of Radiation Oncology! We’re excited for the leadership, expertise, and vision Dr. Takiar brings to our team. #Welcome #RadOnc @PennStHershey
🧵1/ 🚨New case report out in Cureus: Face the Pain: Radiobiological and Clinical Considerations of Re-radiosurgery to the Trigeminal Nerve 👉 A deep dive into a unique case of medically refractory TGN in the setting of a petroclival meningioma. 🔗 doi.org/10.7759/cureus…
Interested in an updated overview of small cell lung cancer geared towards a general audience? Check out our review article published in JAMA! @Sokim_33 @Annechiangmd @YaleMed @YaleCancer @YaleRadOnc
Small cell lung cancer (SCLC) is a smoking-related malignancy that presents at an advanced stage in 70% of patients. This narrative review summarizes the epidemiology, molecular characteristics, clinical presentation, and management of SCLC. ja.ma/4j5YgRF
Epidural spinal cord compression (ESCC) scale for cancer metastasis
🚨🔥 1/2 @OncoAlert Hot off the press. Just published @NEJM in conjunction with presentation on updated data @myESMO #ESMO2024 Results of #ADRIATIC trial of #Durvalumab vs #Placebo after #Chemoradiotherapy in Limited-Stage #SmallCell #LungCancer. 👇🏼 nejm.org/doi/full/10.10…
🚨Check out this editorial!🚨 “Personalizing Treatment Decisions for Locally Advanced Rectal Cancer to Balance Quality of Life, Function, and Cancer Control” @ASCOPost @ASCO @KarynAGoodman @EricDozoisMD @MayoRadOnc @QuadShotNews @ACROresident #CRC brnw.ch/21wO4pn
There has been a dramatic transformation of care for pts w locally advanced #RectalCancer w overarching goal to better balance disease control w long-term #QoL & function. Experts discuss treatments, recent trial data: brnw.ch/21wO4pn @KrishanJethwa #GICSM #ASCODailyNews
Excited to share about NRG GI-011 (aka LAP100) – anticipated opening in mid/early 2025. In this Phase III RCT, we are assessing the benefit of dose-escalated radiotherapy in patients with locally advanced unresectable pancreas cancer. 🧵1/11
Palliative radiotherapy versus best supportive care in patients with painful hepatic cancer (CCTG HE1) out on @TheLancetOncol thelancet.com/journals/lanon… This phase 3 trial investigated whether radiotherapy ☢️improves hepatic pain in patients with hepatocellular carcinoma or liver…
Just finished learning the AJCC 8th edition? Get ready for the 9th edition in less than 3 months! Kudos for Frank Detterbeck and team for this @accpchest summary of staging updates in lung cancer. @IASLC @YaleCancer @YaleThoracic @YaleRadOnc sciencedirect.com/science/articl…
Preparing to give a lecture on physician wellness & professional fulfillment to med students @CleClinicLCM - here are some useful references 1/
Burnout & moral injury in medicine have affected so many health care workers. As a mid-career physician, here’s what I’ve learned to combat it - I hope others find it to be helpful. In Search of Joy and Meaning in Modern Medicine @JCOOP_ASCO ascopubs.org/doi/pdf/10.120…
Limited stage small cell lung carcinoma treated with concurrent chemo-radiotherapy, adjuvant Durva IO improved OS and PFS, a new standard of care.
NRG GU008 — an important trial for patients with node positive prostate cancer. Currently open and enrolling patients!
#PRIMR creates compelling videos for doctors and patients. INNOVATE trial: apalutamide + standard treatment = better outcomes? To enroll, patients must have lymph node-positive prostate cancer + elevated PSA after surgery. Watch: primrmed.com/cancer-clinica… @RonaldChenMD @NRGonc
ARS Appropriateness Use Criteria for Unresectable Locally Advanced Non–Small Cell Lung Cancer Strong push for IMRT; discussion of nuances for PD-L1 negative / EGFR mutant / poor performance status or pulmonary function Kudos to @rad_onc and @KHigginsMD! jamanetwork.com/journals/jamao…
🔥🚨@OncoAlert Hot Off the Press BIG NEWS Press Release by @AstraZeneca #ADRIATIC phase 3 trial of #Durvalumab vs #Placebo after concurrent chemoradiotherapy in pts with limited-stage #SmallCell #LungCancer met dual primary endpoints of ⬆️#OS & ⬆️#PFS 👇🏼 astrazeneca.com/media-centre/p…
.@alexandra_p_24 led a study in @JCO_ASCO showing that using smoking duration, instead of pack-years, to determine #lungcancerscreening eligibility is more equitable and greatly increases opportunities for early lung cancer detection. ascopubs.org/doi/10.1200/JC…
Updated Analysis of Comparative Toxicity of Proton and Photon Radiation for Prostate Cancer | Journal of Clinical Oncology ascopubs.org/doi/10.1200/JC… 11 years ago we published our findings of no difference. Given more time and more progress, we looked again… @cpgYALE @YaleCOPPER
Check out our work culminating in a web tool to predict the risk of brain metastasis in patients newly diagnosed with cancer! Paper: pubmed.ncbi.nlm.nih.gov/38388667/ Webtool: tinyurl.com/brain-mets Thanks to all of our collaborators especially @NicholasZaorsky and @mwang_cwru!!
Estimating the risk of brain metastasis for patients newly diagnosed with cancer Our team built highly predictive models to help physicians and @NCCN guidelines in recommending brain MRI pubmed.ncbi.nlm.nih.gov/38388667/ rdcu.be/dzlqQ Webtool: tinyurl.com/brain-mets
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