JAustin_Science's profile picture.

James Austin

@JAustin_Science

James Austin reposted

Hooray to this good soul for this wonderful diagram for understanding neutralising antibody graphs. And remember folks neut Ab are v important but other parts of the immune system can kick in (binding antibodies, T cells in particular) and may prevent severe disease

Here is my (hopefully) simple guide to interpreting Neutralisation data charts

TheGazmanRants's tweet image. Here is my (hopefully) simple guide to interpreting Neutralisation data charts


James Austin reposted

To those who have had the infection and are relying on that to keep them protected - here is the evidence for vaccination from the #SIREN study led by @SMHopkins: The problem is your protection from natural infection will wane.

LanceTurtle's tweet image. To those who have had the infection and are relying on that to keep them protected - here is the evidence for vaccination from the #SIREN study led by @SMHopkins:

The problem is your protection from natural infection will wane.

The immune system didn't evolve to stop you being PCR positive for respiratory viruses, it evolved to stop you dying. Bottom line - get vaccinated and get that booster dose! 5/5



James Austin reposted

A novel NETs assay directly reflects NETs deposition within lungs and could be used to guide therapeutic targeting of CXCR1/2 in sepsis @BJAJournals @CHToh1 bit.ly/3IxHERm

BJAJournals's tweet image. A novel NETs assay directly reflects NETs deposition within lungs and could be used to guide therapeutic targeting of CXCR1/2 in sepsis
@BJAJournals @CHToh1 

bit.ly/3IxHERm

James Austin reposted

Great to have our work on immune response after extended dosing interval for Pfizer BNT162b2 now formally out in peer review in Cell. Here's a 🧵from 1 of the paper's 1st authors outlining the paper. Great teamwork from the many involved - see end of thread for collaborators 👋

1/ Proud to be part of this @pitchstudy ‘Immunogenicity of standard and extended dosing intervals of @pfizer BNT162b2 mRNA vaccine’ which is out in @CellCellPress cell.com/cell/fulltext/… Thread below 👇



James Austin reposted

1/ Proud to be part of this @pitchstudy ‘Immunogenicity of standard and extended dosing intervals of @pfizer BNT162b2 mRNA vaccine’ which is out in @CellCellPress cell.com/cell/fulltext/… Thread below 👇


James Austin reposted

Well done team - a massive effort by many many people. Liverpool team includes @ShonaCMoore @JAustin_Science , Luisa Hering, Dan Wootton and Andy Cross (not on Twitter) @HPRUezi @LivUni_IVES @livuninews *ignored the “do you want to read the article first” message!* 😆


Having the monsters around for the monster mash was a good idea - Worth the post-night nightmares #MumsBirthday !

JAustin_Science's tweet image. Having the monsters around for the monster mash was a good idea - Worth the post-night nightmares #MumsBirthday !

Just won a £10 off a meal at the pub quiz @ElephantWoolton - my tacky taste in music finally come good 😂.


James Austin reposted

Proud to be part of such a great team @pitchstudy. Massive congratulations to all involved @JessTyerman @chrisjaduncan @rebecca37704429 @Susannajd et al. Big thanks to the participants and the staff @NewcastleHosps

Our @pitchstudy paper on the impact of Pfizer dosing interval (which we preprinted in July) is now live @CellCellPress. Many thanks to all our many collaborators & the HCWs who participated @LanceTurtle @Thushan_deSilva @Carroll_Lab_Ox @AlexRichter3 @chrisjaduncan Chris Dold



James Austin reposted

Graphical abstract designed by @UniofNewcastle PhD student @Alex_MRCDiMeN


James Austin reposted

Our @pitchstudy paper on the impact of Pfizer dosing interval (which we preprinted in July) is now live @CellCellPress. Many thanks to all our many collaborators & the HCWs who participated @LanceTurtle @Thushan_deSilva @Carroll_Lab_Ox @AlexRichter3 @chrisjaduncan Chris Dold

Our @pitchstudy paper on the impact of Pfizer dosing interval (which we preprinted in July) is now live @CellCellPress. Many thanks to all our many collaborators & the HCWs who participated @LanceTurtle @Thushan_deSilva @Carroll_Lab_Ox @AlexRichter3 @chrisjaduncan Chris Dold



James Austin reposted

Just Realised @rebecca37704429 was not tagged in original post - Becky led the first author team and brought this story all together


One is good, Two is better - Longer is stronger ? Our COVID publication looking at differences in Pfizer dosing regimens in non and previously infected subjects is now Live in Cell. cell.com/cell/fulltext/…


James Austin reposted

Fantastic collaboration lead superbly by @Susannajd . Lots of Elispots @sfaustini

Our @pitchstudy paper on the impact of Pfizer dosing interval (which we preprinted in July) is now live @CellCellPress. Many thanks to all our many collaborators & the HCWs who participated @LanceTurtle @Thushan_deSilva @Carroll_Lab_Ox @AlexRichter3 @chrisjaduncan Chris Dold



James Austin reposted

Congrats to the first authors @rebecca37704429 @stephanie200586 @JAustin_Science @skellydonal and to all the other contributors. Excellent team effort!


James Austin reposted

One day there'll be a national PITCH get together, but for now here was some of Oxford plus remote celebration from Liverpool

pitchstudy's tweet image. One day there'll be a national PITCH get together, but for now here was some of Oxford plus remote celebration from Liverpool

James Austin reposted

We are happy to announce that we are working with @PHE_uk on an exciting new study seeking to understand why some people become infected after vaccination or prior infection while others do not. Read more at: oxfordbrc.nihr.ac.uk/new-study-laun… @NDMOxford @OxfordMedSci


James Austin reposted

As we enter ‘code red’ in the #ClimateEmergency, photographers share how #photography can help to raise environmental awareness, start conversations and inspire urgent action. greenpeace.org/international/…


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