Our new paper! It was amazing to work with such a great group of collaborators to bring together many types of data to explore the roles of pfaat1 and pfcrt in malaria drug resistance and fitness.
Out now in @NatureMicrobiol: Chloroquine resistance evolution in P. falciparum is mediated by the putative amino acid transporter AAT1 By Alfred Amambua-Ngwa, Timothy Anderson & colleagues. @txbiomed @seattlechildren @NotreDame @LSHTM nature.com/articles/s4156…
nature.com
Chloroquine resistance evolution in Plasmodium falciparum is mediated by the putative amino acid...
Nature Microbiology - Chloroquine resistance in Plasmodium falciparum is characterized using population genomics, genetic crosses and gene editing.
It is so exciting to see our new MCC preprint out. We teamed up with great collaborators to bring together historical population genomic data, genetic crosses and CRISPR editing to investigate pfaat1 biorxiv.org/content/10.110…
Button-Simons et al. describe two distinct genetic crosses of Plasmodium falciparum derived from parasites of Asian and African origin with the potential to map biologically important traits across parasite genomes. @mferdiglab @doubleholliday2 nature.com/articles/s4200…
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