Collier Lab
@LabCollier
Joel Collier’s Biomaterials for Immunoengineering Lab @DukeU http://collier.pratt.duke.edu
Check out our latest publication - Differential Sensitivity to Interepitope Spacing in Mast Cells and B Cells Enables Design of Hypoallergenic Allergen Vaccine Immunogens | ACS Nano pubs.acs.org/doi/10.1021/ac… Congrats to Ben Cossette and co-authors!
pubs.acs.org
Differential Sensitivity to Interepitope Spacing in Mast Cells and B Cells Enables Design of...
Therapeutic allergen vaccine immunogens can trigger IgE-mediated mast cell activation, resulting in allergic reactions. Here, we report on a mode of hypoallergenic immunogen design that enables...
Looking forward to #SFB2025 this week! I will be presenting my current work on a targetless immunotherapy for septic shock. Hope to see you there!
🔥New Collier Lab publication🔥 We employed supramolecular peptide nanofibers to interfere with C3a and C5a activity in vivo and better understand the role of both anaphylatoxins in LPS-induced sepsis. Congrats @HFreireHaddad and co-authors! onlinelibrary.wiley.com/doi/full/10.10…
advanced.onlinelibrary.wiley.com
Multi‐Target Peptide Nanofiber Immunotherapy Diminishes Complement Anaphylatoxin Activity in Acute...
This study investigates an active immunotherapy platform based on supramolecular peptides that can target two complement anaphylatoxins, C3a and C5a, to diminish acute inflammation. The materials’...
Congratulations to Ben Cossette for defending his thesis today, titled “Engineering Hypoallergenic Allergen Vaccine Immunogens Based on Self-Assembling Supramolecular Peptide Nanofibers”. Good luck on your next adventures, we will miss you! 🥜👨🏻🔬
Congratulations to Joel Collier @DukeU on receiving the prestigious Clemson Award for Basic Research from @SFBiomaterials for his seminal contributions to biomaterials field! The award was presented @ SFB Southeast Symposium held @ibbgatech along w/ a live streamed plenary talk!
Excited to have been present in an outstanding presentation by @Collier_Joel today during his SFB Clemson Award Talk for Basic Science. Amazing work! Congratulations Joel! 🎉 Excited to be your colleague @DukeUBME @DukeEngineering
New Collier lab publication! We utilized supramolecular peptide materials in an anti-cytokine active immunotherapy to target IL-1B mediated inflammation. Congrats Shamitha Shetty and co-authors! onlinelibrary.wiley.com/doi/10.1002/ad…
advanced.onlinelibrary.wiley.com
Anti‐Cytokine Active Immunotherapy Based on Supramolecular Peptides for Alleviating IL‐1β‐Mediated...
Supramolecular peptide nanofiber immunogens are designed using B-cell epitopes from IL-1β and exogenous T-cell epitopes. Without adjuvant, these materials raise durable antibody responses that...
Our lab members attended @DukeUBME department retreat early this week. We won best group video for the rapid fire talks! 🏖️🔬
🔥New publication in @ACSBiomaterials: Supramolecular Peptide Self-Assemblies Facilitate Oral Immunization Congrats to @ECurvino and co-authors @miawoodruff1 Emily Roe @HFreireHaddad @PabloCorderoA doi.org/10.1021/acsbio…
pubs.acs.org
Supramolecular Peptide Self-Assemblies Facilitate Oral Immunization
Oral immunization is a promising strategy for preventing and treating gastrointestinal (GI) infections and diseases, as it allows for direct access to the disease site. To elicit immune responses...
Huge congratulations to @LabCollier superstar undergrad @miawoodruff1 ! Mia was awarded with the NSF GRFP and will be joining @WilsonLabVU at @VanderbiltU in the Fall. We are so proud!
New publication alert! We developed a complement C5a-targetting active immunotherapy with applications in models of sepsis and arthritis. Congrats Kelly Hainline and co-authors @HFreireHaddad Anna Gilpin @ECurvino @shynivarghese sciencedirect.com/science/articl…
Check out our new publication in ACS Biomaterials Science & Engineering. Congrats to first author Ben Cossette and all coauthors! 👨🔬💉 pubs.acs.org/doi/10.1021/ac…
pubs.acs.org
Self-Assembling Allergen Vaccine Platform Raises Therapeutic Allergen-Specific IgG Responses...
Allergen immunotherapies are often successful at desensitizing allergic patients but can require life-long dosing and suffer from frequent adverse events including instances of systemic anaphylaxis,...
Congratulations to two of our favorite @DukeUBME friends, @seguralab for the Clemson award for contribution to the literature and @LabCollier for the Clemson award for basic research. So fortunate to have such incredible colleagues!!!
🌟Exciting News!🌟 Announcing the 2024 Society For Biomaterials Award Recipients! 🏆 Join us in celebrating excellence & achievement as we proudly unveil the outstanding individuals who have left an indelible mark on our Society. 🎉👏🎉bit.ly/3tJVuOb
Congrats to our @SFBImmuneEng @SFBiomaterials awardees Tanvi Pathrikar @BajpayeeLab, @HFreireHaddad @LabCollier, and Rebeca Stiepel @AinslieLab! Amazing Webinar talks yesterday! (also to Sehwan Jeong who could not make it). Thanks also to our SFB/IE community for your support!
🚨New @LabCollier paper🚨 We took advantage of natural antibodies against phosphorylcholine to design a supramolecular peptide nanofiber active immunotherapy for IBD. 🎉Congrats @ECurvino and co-authors! @seguralab @HFreireHaddad @miawoodruff1 @aalexaandersonn
Engaging natural antibody responses for the treatment of inflammatory bowel disease via phosphorylcholine-presenting nanofibres rdcu.be/dr9Bd
New Project is up in our website! A few months ago @PabloCorderoA passed his prelim exam and became a PhD candidate. In my lab, when students complete this major milestone, we celebrate their success and add their project to our lab website with a unique logo.
Make sure to check out Helena’s presentation on her award-winning poster from SFB Immune Engineering SIG on Dec 6th at 12:00 pm! bit.ly/3Fy3luU
Exciting News! Join us for the Immune Engineering SIG's webinar featuring talks from their 2023 Poster Awardees. 🏆 Don't miss three great research presentations on December 6th at 12 PM ET. Mark your calendars! 🗓️ bit.ly/3Fy3IuU @SFBImmuneEng #ImmuneEngineering
If you’re at BMES this week, check out some of the work from our group on Thursday and Friday. See you in Seattle!
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