SchragLab
@LabSchrag
We study shared molecular mechanisms between Alzheimer's disease and Cerebral Amyloid Angiopathy
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#MondayTip 📊Pooled INTERACT data ✅Intensive BP lowering improves recovery in ICH ⏱️When started <3h (cutoff: 2.6h)➡️reduces haematoma growth ☝️Greatest benefit in mild–moderate ICH (ICH score) 🚨Early treatment improves outcomes👉supports CODE-ICH systems & future trial design
🎉 Congratulations to @hamm_heidi of @VandyPharm and @EricSkaar on being elected to @theNASciences! Their groundbreaking contributions to biomedical #research have earned them one of the highest honors in #science. 👏🏾👏👏🏻👏🏽 news.vumc.org/2025/05/08/hei…
news.vumc.org
Heidi Hamm, Eric Skaar elected members of the National Academy of Sciences
Two Vanderbilt faculty members have been elected members of the National Academy of Sciences in recognition of their research achievements.
Today, the New England Journal of Medicine published what may be a landmark moment: doctors used customized gene editing inside a living baby to treat a deadly genetic disease called carbamoyl-phosphate synthetase 1 (CPS1) deficiency. Is it time to prepare for a world where we…
Another great @VUMCDiscoveries Stroke Symposium @schrag_matthew !!! Dr. Eliza Miller was an amazing speaker and I learned so much more about stroke in pregnancy ! Shoutout to my mentee on his awesome poster!
Congratulations Angela, huge accomplishment.
I am honored + humbled to have been elected as a 2024 Fellow of the American Association for the Advancement of Science. @AAAS Fellows are distinguished scientists, engineers, + innovators across the globe. It is a privilege be part of such an illustrious group.
I am honored + humbled to have been elected as a 2024 Fellow of the American Association for the Advancement of Science. @AAAS Fellows are distinguished scientists, engineers, + innovators across the globe. It is a privilege be part of such an illustrious group.
Congratulations to the new 2024 AAAS Fellows class! They are a distinguished cadre recognized for their achievements across disciplines, including research, and teaching. aaas.org/news/aaas-welc…
Today at NANOS 2025, NANOS Board Member, Larry Frohman, MD presented the prestigious Thomas Carlow Distinguished Service Award to the incomparable (and legendary) Valerie Biousse, MD to a standing ovation. #nanos #nanos2025 #nanosconnect #nanosannualmeeting
Come to this year’s Vanderbilt Stroke Symposium- live or virtual. Would be great to connect at this outstanding annual CME event.
Congratulations to the new 2024 AAAS Fellows class! They are a distinguished cadre recognized for their achievements across disciplines, including research, and teaching. aaas.org/news/aaas-welc…
We are pushing the last inclusions in @TenCRAOS - 76 down, 2 to go! Soon time to prepare for presentation at #ESOC2025 in #Helsinki ! @IjasPetra @maztrocyte @LaurenSanders81 @clauszsimonsen @ESOstroke @LHL_Hjerneslag @Blindeforbundet eso-stroke.org/events/esoc-20…
It is with great pleasure that we anoint another chair from our division--please join us in congratulating *THE* Pooja Khatri on her new position as Chair of Neurology at Yale! Thank u for everything that u continue to do for us and for our patients!!! 🥳🥰
Promising result from THEIA trial for tPA in CRAO. Missed primary endpoint, but encouraging trend and acceptable safety. Congrats to THEIA team. @TenCRAOS and REVISION trials next. @SvenPoli @brianmacgrory @vbiouss @OanaDumitrascu5 @AnneHegeAamodt medscape.com/viewarticle/th…
Minimally Invasive Surgery for Spontaneous ICH: Meta‐Analysis of High‐Quality Randomized Clinical Trials Over 3000 pts in 14 high quality trials MIS wins! Nice work @chriskellnerMD and all! onlinelibrary.wiley.com/doi/10.1002/an…
Does prior treatment with IV thrombolysis lead to improved outcome after stroke #thrombectomy? Yes! Says this big meta-analysis. The authors said “we did not establish non-inferiority” of prior lysis I think that means prior lysis is better 🤔 thelancet.com/journals/lance…
Previously published work from the lab led by @Hyosung_Bio highlighting the relationship between astrocytic SERPINA3 and blood-brain barrier properties can be read about here! nature.com/articles/s4146…
nature.com
Reactive astrocytes transduce inflammation in a blood-brain barrier model through a TNF-STAT3...
Nature Communications - Inflammation of brain endothelial cells is seen in neurodegenerative conditions and in aging. Here the authors examine the role of astrocytes in blood brain barrier function...
Have you ever seen a case of autosomal dominant Alzheimer’s w/ ribbon like cortical calcifications? Wang and colleagues show us a case in @GreenJournal. Key Points: - The person had ‘recurrent headaches for 20 years, walking instability for 8 years, and memory loss and…
The countdown has begun!! Amazing work again by @AUHdk @clauszsimonsen and the ophthalmologists. Aarhus has now recruited their 11th patient and our study has just 10 to go. 68/78 So exciting! @IjasPetra @DrPeterVanacker @LouisaMChriste1 @LaurenSanders81 @Khanevski @maztrocyte
Tranexamic acid vs placebo within 2 h of #ICH onset (STOP-MSU): an international, double-blind, trial Primary outcome measure was ICH growth. Turns out that TXA has absolutely NO effect on ICH expansion, which was ~30% in both groups. Zilch. Nada. thelancet.com/journals/laneu…
It’s stroke symposium time - tomorrow (Thursday). Not too late to sign up.
It’s not too late to register for Vanderbilt’s annual Stroke Symposium taking place this Thursday (tomorrow!) Virtual attendance is available. Get CME credit and up to date. Registration: eventbrite.com/e/26th-annual-…
eventbrite.com
26th Annual Vanderbilt Neurology Stroke and Neuroscience Symposium
Don't miss this highly anticipated event to learn about recent advances in stroke care from prominent experts!
Shoutout to @anackenoff who did some of the foundational technical work for this project, to @LippmannLabVU for a major contribution and imaging expertise from Jose Maldonado/Neurovisualization lab. Preliminary draft at the link and we welcome feedback. biorxiv.org/content/10.110…
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