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MacMODR's profile picture. McMaster's Centre for Metabolism, Obesity & Diabetes Research translates world leading basic science into clinical practice to improve metabolic disease.

@MacMODR

@MacMODR

McMaster's Centre for Metabolism, Obesity & Diabetes Research translates world leading basic science into clinical practice to improve metabolic disease.

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@MacMODR
 @MacMODR
Oct 17

New research in @CommsMedicine from @machealthsci & @PHRIresearch investigators shows that hidden abdominal & liver fat may silently harm arteries even in those who look healthy. healthsci.mcmaster.ca/skinny-fat-lin…

MacMODR's tweet image. New research in @CommsMedicine from @machealthsci & @PHRIresearch investigators shows that hidden abdominal & liver fat may silently harm arteries even in those who look healthy. healthsci.mcmaster.ca/skinny-fat-lin…
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jclinicalinvest's profile picture.
Journal of Clinical Investigation
@jclinicalinvest
Sep 18

MASH: the nexus of metabolism, inflammation and fibrosis This review by Gregory R. Steinberg @DrGregSteinberg & colleagues @McMasterU is part of JCI’s ongoing series, Evolving Insights into #MASLD and MASH Pathogenesis and Treatment with series editor Scott Friedman:…

jclinicalinvest's tweet image. MASH: the nexus of metabolism, inflammation and fibrosis This review by Gregory R. Steinberg @DrGregSteinberg & colleagues @McMasterU is part of JCI’s ongoing series, Evolving Insights into #MASLD and MASH Pathogenesis and Treatment with series editor Scott Friedman:…
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EricMDesjardins's profile picture.
Eric M. Desjardins
 @EricMDesjardins
Aug 1

Targeting hepatocyte and tumour lipid metabolism through ACLY inhibition promotes B-cell infiltration/aggregation via CXCL13, resulting in reduced tumour burden in MASH-HCC mouse models nature.com/articles/s4158…

EricMDesjardins's tweet card. Nature - Using metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma mouse models, an ATP citrate lyase inhibitor reduces tumour burden and enhances efficacy of current...
ACLY inhibition promotes tumour immunity and suppresses liver cancer
Source: nature.com
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Jul 31

“This is one of the first studies to show that targeting metabolism in tumours can enable the immune system to kill liver cancer cells, and opens the door to more effective prevention and treatment strategies for this deadly disease,” @DrGregSteinberg healthsci.mcmaster.ca/mcmaster-resea…

healthsci.mcmaster.ca

Promising new treatment for liver cancer

Liver cancer cells thrive on fat, posing a serious risk of cancer diagnosis for millions of people living with fatty liver disease. But researchers at McMaster University in collaboration with...

Source: healthsci.mcmaster.ca
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Cell Metabolism
 @Cell_Metabolism
Jul 29

New! Online now: Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice dlvr.it/TMB0yf

Cell_Metabolism's tweet image. New! Online now: Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in obese mice dlvr.it/TMB0yf
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machealthsci's profile picture.
McMaster Health Sciences
@machealthsci
Jul 29

Researchers from across @McMasterU’s Faculty of Health Sciences have secured nearly $19M from @CIHR_IRSC’s Spring 2025 Project Grant Competition. Explore the full list of newly funded research teams and topics 👇 ow.ly/V8ab50WwI1S

machealthsci's tweet card. The Canadian Institutes of Health Research (CIHR) has invested more than $18.8 million in 28 projects led by McMaster University’s Faculty of Health Sciences (FHS) following the Spring 2025 Project...
CIHR awards Health Sciences researchers nearly $19M - Faculty of Health Sciences
Source: healthsci.mcmaster.ca
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Jul 30

Published in @Nature, the findings offer a promising path to better prevention & treatment strategies. nature.com/articles/s4158…

MacMODR's tweet card. Nature - Using metabolic dysfunction-associated steatohepatitis-driven hepatocellular carcinoma mouse models, an ATP citrate lyase inhibitor reduces tumour burden and enhances efficacy of current...
ACLY inhibition promotes tumour immunity and suppresses liver cancer
Source: nature.com
MacMODR's profile picture. McMaster's Centre for Metabolism, Obesity & Diabetes Research translates world leading basic science into clinical practice to improve metabolic disease.
@MacMODR
 @MacMODR
Jul 30

Liver cancer rates are📈in Canada, driven by #fattyliverdisease 🔗to #obesity & #diabetes. Current treatments are limited. Researchers @MacMODR & #EspervitaTherapeutics developed a drug that blocks fat production in tumors, helping #Bcells attack cancer.

MacMODR's tweet image. Liver cancer rates are📈in Canada, driven by #fattyliverdisease 🔗to #obesity & #diabetes. Current treatments are limited. Researchers @MacMODR & #EspervitaTherapeutics developed a drug that blocks fat production in tumors, helping #Bcells attack cancer.
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Jul 30

Liver cancer rates are📈in Canada, driven by #fattyliverdisease 🔗to #obesity & #diabetes. Current treatments are limited. Researchers @MacMODR & #EspervitaTherapeutics developed a drug that blocks fat production in tumors, helping #Bcells attack cancer.

MacMODR's tweet image. Liver cancer rates are📈in Canada, driven by #fattyliverdisease 🔗to #obesity & #diabetes. Current treatments are limited. Researchers @MacMODR & #EspervitaTherapeutics developed a drug that blocks fat production in tumors, helping #Bcells attack cancer.
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Daniel J Drucker
 @DanielJDrucker
Jul 29

Here Professor Schertzer and colleagues identify that microbial-derived D-lactate contributes to host glucose and lipid metabolism and can be trapped therapeutically to improve metabolic disease during #obesity cell.com/cell-metabolis…

DanielJDrucker's tweet card. D-lactate from the gut microbiota influences blood glucose and fatty liver disease. Trapping D-lactate in the gut improves blood glucose and lowers liver inflammation and fibrosis during obesity.
Gut substrate trap of D-lactate from microbiota improves blood glucose and fatty liver disease in...
Source: cell.com
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McMaster Health Sciences
@machealthsci
Jul 29

Researchers from @McMasterU @universitelaval @uOttawa have made a discovery that could open the door to new therapies to treat metabolic diseases like type 2 diabetes and fatty liver disease. Learn more: healthsci.mcmaster.ca/trapping-gut-b… @CIHR_IRSC @Farncombe_GI @MacMODR

machealthsci's tweet card. A team of Canadian scientists has discovered a surprising new way to improve blood sugar levels and reduce liver damage: by trapping a little-known fuel made by gut bacteria before they wreak havoc...
Trapping gut bacteria’s hidden fuel improves blood sugar and liver health, study shows - Faculty of...
Source: healthsci.mcmaster.ca
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@MacMODR
 @MacMODR
Jul 29

sciencedirect.com/science/articl…

MacMODR's profile picture. McMaster's Centre for Metabolism, Obesity & Diabetes Research translates world leading basic science into clinical practice to improve metabolic disease.
@MacMODR
 @MacMODR
Jul 29

New findings from @Schertzerlab out in @cellmetabolism show that trapping microbial D-lactate in the gut ⬇️#bloodglucose, #liverinflammation & #fibrosis in #obese mice. D-lactate⬆️#bloodglucose through a shunt in the #Coricycle, adding to a 100-year-old discovery.

MacMODR's tweet image. New findings from @Schertzerlab out in @cellmetabolism show that trapping microbial D-lactate in the gut ⬇️#bloodglucose, #liverinflammation & #fibrosis in #obese mice. D-lactate⬆️#bloodglucose through a shunt in the #Coricycle, adding to a 100-year-old discovery.
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Jul 29

New findings from @Schertzerlab out in @cellmetabolism show that trapping microbial D-lactate in the gut ⬇️#bloodglucose, #liverinflammation & #fibrosis in #obese mice. D-lactate⬆️#bloodglucose through a shunt in the #Coricycle, adding to a 100-year-old discovery.

MacMODR's tweet image. New findings from @Schertzerlab out in @cellmetabolism show that trapping microbial D-lactate in the gut ⬇️#bloodglucose, #liverinflammation & #fibrosis in #obese mice. D-lactate⬆️#bloodglucose through a shunt in the #Coricycle, adding to a 100-year-old discovery.
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Feb 27

Another great addition to our March 6 seminar is Maya Bozzo-Rey – MSc (c) in @SergiClotet lab. Her presentation will explore kidney metabolism, epigenetics & sex differences in DKD, with a focus on metabolic responses to high glucose & epigenetic modifications.

MacMODR's tweet image. Another great addition to our March 6 seminar is Maya Bozzo-Rey – MSc (c) in @SergiClotet lab. Her presentation will explore kidney metabolism, epigenetics & sex differences in DKD, with a focus on metabolic responses to high glucose & epigenetic modifications.
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Feb 27

Also presenting on March 6 is Meghan Conn – 2nd year MSc (c) in the @SchertzerLab. @MeghanConn01's presentation will describe the metabolic changes that occur during repeated intermittent fasting(IF) & how features of obesity & early T2D affect the metabolic response to IF

MacMODR's tweet image. Also presenting on March 6 is Meghan Conn – 2nd year MSc (c) in the @SchertzerLab. @MeghanConn01's presentation will describe the metabolic changes that occur during repeated intermittent fasting(IF) & how features of obesity & early T2D affect the metabolic response to IF
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MacMODR's profile picture.
@MacMODR
 @MacMODR
Feb 27

Join us on March 6 for the next MODR Seminar, featuring #MODRtrainee Ann Kuganathan - 4th-year PhD(c) in the Krepninsky lab. @annswathyk will share her research on how follistatin improves vascular health & PVAT function in hypertension. 🔗…bolism-research.healthsci.mcmaster.ca/events/modr-se…

MacMODR's tweet image. Join us on March 6 for the next MODR Seminar, featuring #MODRtrainee Ann Kuganathan - 4th-year PhD(c) in the Krepninsky lab. @annswathyk will share her research on how follistatin improves vascular health & PVAT function in hypertension. 🔗…bolism-research.healthsci.mcmaster.ca/events/modr-se…
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McMaster Child Health Research
 @McMasterCHR
Feb 24

Good luck to all the learners, research staff, as well as family partners and new investigators putting the finishing touches on their #MCHRD2025 abstracts! Remember to submit your abstracts by this Wed. Feb. 26 at 11:59 PM EST via the MCHRD website ⬇️ pediatrics.healthsci.mcmaster.ca/research/mcmas…

McMasterCHR's tweet image. Good luck to all the learners, research staff, as well as family partners and new investigators putting the finishing touches on their #MCHRD2025 abstracts! Remember to submit your abstracts by this Wed. Feb. 26 at 11:59 PM EST via the MCHRD website ⬇️ pediatrics.healthsci.mcmaster.ca/research/mcmas…
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Melanie G Cree, MD, PhD

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Mac Prog for FacDev

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Bounce McMaster

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smitaluna's profile picture. Assoc Prof in GI @MacDeptMed | Senior Medical Officer @HamHealthSci | Master Certified Physician Development Coach| Wife,Mum,Medical Leader | Mcr➡️TO🇬🇧🇨🇦

Dr Smita Halder

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McMaster Engineering

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The Research Institute of St. Joe's Hamilton

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NASPEM

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Frank Ong

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Cell Reports Medicine

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Evelyn Tsakiridis

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Nature Reviews Endocrinology

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McMaster MPH Program

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McMaster SGS

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McMaster Faculty of Science

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Laiba

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TaARI_Canada

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Canadian Paediatric Society

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ChildObesity_jn's profile picture. The only peer-reviewed journal focused on actionable strategies to manage & prevent #obesity in children & adolescents

Childhood Obesity

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SUPRECONTENT's profile picture. We make films about health.

SUPRE

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paiPad's profile picture. Pediatric GI. Associate Professor. Microbial medicine researcher. All things: microbiome, nutrition, MASLD, child health. Proud papa. Made in Canada. OAMO.

Nikhil Pai (MD, CNSC, NASPGHAN-F, FRCPC, FAAP)

@paiPad
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CanChild Centre for Childhood Disability Research

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Cheryl C

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Stacey Marjerrison

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JCampbellLab's profile picture.

Jonathan Campbell

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ObesityAction's profile picture. The Obesity Action Coalition (OAC) is a National non-profit dedicated to improving the lives of those with obesity through education, advocacy & support.

OAC

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The Obesity Society

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WinRS

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DrBasmaAhmed's profile picture. MBBCh, MSc, PhD | Laboratory Medicine | Clinical Biochemistry is my passion | Metabolic health|

Basma Ahmed

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HATCHmcmaster's profile picture. Identify, evaluate & advocate for evidence-based interventions to improve the health of underserved children in #HamOnt & surrounding region.

HATCHmcmaster

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MSc Health Sci Education (HSED)

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Emilio Mottillo

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McMaster OCE

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SheriNsamenang's profile picture. Clinical & Health Psychologist at McMaster; Assistant Professor; Mother of 2 Boys; Living Intentionally and Non-judgementally; Striving for Wholeheartedness

Sheri

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itsdocfoley's profile picture. Science is the sport. Metabolism is my game....and hockey. Cats beat dogs, can't change my mind.

Kevin Foley

@itsdocfoley
clsa_elcv's profile picture. Canadian Longitudinal Study on Aging/l'Étude longitudinale canadienne sur le vieillissement. Long-term, national research platform following 50,000 participants

Canadian Longitudinal Study on Aging (CLSA)

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McMaster FHS Faculty Affairs

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ObesityCareWeek's profile picture. Obesity Care Week has a global vision for a society that understands, respects & accepts the complexities of obesity. #ObesityCareWeek

Obesity Care Week

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seanwharton's profile picture. Physician, general internal medicine, UofT graduate from Medicine and PharmD, McMaster residency. obesity medicine clinician and researcher

sean wharton

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matthewhirschey's profile picture. academic scientist. also building @heurekalabs . like the chocolate.

Matthew Hirschey💡

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IntJObesity's profile picture. IJO is a leading multidisciplinary obesity journal w/ 5yr impact factor 5.544; Publisher: @SpringerNature

International J Obesity

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Research Canada

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