Martinac Lab
@Martinac_Lab
Research in the Martinac laboratory focuses on ion-channel mediated mechanosensory transduction processes in living cells from bacteria to humans.
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Great review on mechanosensivity of TRP channels. Conclusion: if any TRP channels are primary mechanotransducers, most robust evidence for NOMPC and TRPV4, they are activated under specific mechanical conditions and may require auxiliary components. cell.com/trends/biochem…
A pervasive view is that TRP channels represent primary sensors of mechanical forces. Along with @PooleLab1 and @BorisMartinac we reviewed the evidence supporting this in @TrendsBiochem cell.com/trends/biochem…
We are almost full! Just a few months away from the Ion Channels GRS/GRC. If you’re considering attending, apply/register ASAP. It’s going to be fun!!!
Excited to share our latest collaboration with the @corrylab and Zhang Lab, this time on OSCA/TMEM63 channels out today in @Nature @VictorChangInst nature.com/articles/s4158…
Recently Published: High-content method for mechanosignaling studies using IsoStretcher technology and quantitative Ca2+ imaging applied to Piezo1 in cardiac HL-1 cells dlvr.it/T46Dgk
We used FIB-SEM and single corpuscle electrophysiology to determine the 3D structure of Meissner (Grandry) corpuscle and reveal active role of lamellar cells in touch detection. A study by @Yury_A_Nikolaev and Luke Ziolkowski. science.org/doi/full/10.11…
So excited together with @yiechanglin to have been part of this amazing study in @ScienceMagazine led by the labs of @Charles_D_Cox and Yixiao Zhang, who worked out why Piezo channels have different personalities in different cell types. science.org/doi/10.1126/sc…
Super happy to share new work from my lab at @VictorChangInst published today in @ScienceMagazine. Collaborative effort driven by amazing post doc Zijing Zhou with Yixiao Zhang's group and the labs of Richard Harvey, @DrNatashaHarvey and @CorryLab science.org/doi/10.1126/sc…
Post-doc position available in the Martinac Lab. Structure + function of mechanosensitive channels as part of an NIH project with Thomas Walz’s Lab at Rockefeller.
Congratulations to Professor @kovacic_jason appointed the next @OzCvA President. Prof Kovacic looks forward to targeting unmet needs in cardiovascular and stroke health, working closely with government, health, and industry partners: victorchang.edu.au/news/new-acva-…
Very happy to share our work on #SCAD genetics out today @NatureGenet We report exciting results supporting high polygenic heritability, variations mainly related to regulation #SMC #ECM and Tissue coagulation @ERC_Research @parcc_inserm @univ_paris_cite nature.com/articles/s4158…
📣 Our #PaulKornerSeminar starts at 12pm! Today some of our new starters will be presenting their PhD research: Qi (Kevin) Wu from @Renjing_Liu Lab, Kevin Law from @Martinac_Lab, Farzaneh Omidkhoda from Harvey Lab, and Sanjay Dutta and Christian Said from Macdonald/Hayward Lab.
Together, @JeromeMechBio @lyna_yunluo & @Charles_D_Cox & I are putting together a member-organized session at #BPS2023 @BiophysicalSoc on Mechanosensitive Membrane Proteins. Have a new #MechanoMembraneProtein story to share? Time is short! Email your abstract to us by Sep 9!!
Biophysical Society Announces 2023 Society Fellows biophysics.org/news-room/biop…
For registrants of the 4th International Symposium on Mechanobiology in Sydney: check out the amazing conference dinner venue (Museum of Contemporary Art Australia) with spectacular views of the Opera House and Harbour Bridge. mca.com.au/venue-hire/har…
Abstracts and early bird registration will be closing soon for the 4th International Symposium on Mechanobiology (JULY 31st)! Make sure to book your spot at the conference dinner, a venue that over looks the Opera House is surely not to be missed!
New research published in @NatureCVR shows that the stretch-activated, calcium-permeable Piezo1 channel is the mechanosensor that transduces cardiomyocyte stretch into the biochemical signalling pathway leading to #cardiac hypertrophy in mice nature.com/articles/s4156…
Looking forward to seeing all our favorite mechanobiology enthusiasts in Sydney in November. Some exciting developments on the meeting coming soon!
News and Views by @JohannesBacks on the implications of the recent study by @Martinac_lab showing that #Piezo1 links mechanosensation to #cardiac growth nature.com/articles/s4416… @uniklinik_hd, @dzhk_germany 👉rdcu.be/cPDBY
Breakthrough genetic test will pinpoint mutations harmful to the heart - Daily Telegraph - goo.gl/alerts/PZb5t #GoogleAlerts
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