Etienne Baratchart
@MathBioEB
Postdoctoral fellow I splash in #mathematics, swim in #modeling, immerse in #cancer #biology at @mathonco @MoffittResearch and drown in dinosaurs
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1/ We are thrilled to share our latest research in Cancer Discovery! Grateful to all collaborators in this work, work led by Paul Mischel and Ben Werner, and to @drimrannoorani and @magnushaughey for driving this work! Special thanks: team eDyNAmic, UCL, @TheCrick , and CGC/CRUK
A very well-written and thoughtful piece from Itai Yanai and Martin Lercher, with a nice visual showing how we “trim the tree” of the process, for publication. On a related note, I’d like to see more Math Onco papers show the discovery process within papers — e.g. the process of…
This is the first map of human brain mitochondria. 🧵1/11
Still at #ASTRO24? I’m presenting shortly the work of @keyurmedphys who developed an accurate model for toxicity-informed selection of proton therapy for prostate cancer. Join us in Room 145. @MGH_RI @HarvardRadOnc
Published today! We found that cancer cells adapting to drug treatments don't simply switch from a sensitive to resistant state; instead there's a ‘resistance continuum’ of resistant phenotypes with epigenetically reprogrammed states. 🧵⬇️ nature.com/articles/s4158… @Gustavo_SFranca
Powerful Title for a very powerful meeting Defining and Defeating Metastasis Register here 👉🏻embl.org/about/info/cou… @EMBO @embl #Cancer #Metastasis
Does cancer #evolution & intra-tumour heterogeneity predict long-term relapse? We tested the evolutionary paradigm in prostate cancer clinical trials with long follow-up, combining genomics with digital histopathology: nature.com/articles/s4301…
Biological self-organisation at its best! 🤩
Here's the hypnotic time-lapse I used : Dictostelium cAMP signal waves are in gold🟧 and nuclei in Blue🟦, enjoy! I used the dataset from this paper : elifesciences.org/articles/83796
"Adaptive therapy in cancer: the role of restrictions in the accumulation of mutations" biorxiv.org/content/10.110…
Read!!
Here's the hypnotic time-lapse I used : Dictostelium cAMP signal waves are in gold🟧 and nuclei in Blue🟦, enjoy! I used the dataset from this paper : elifesciences.org/articles/83796
I’m delighted that our paper on the Multicellularity Long Term Evolution Experiment (MuLTEE) has, at long last, been published. This paper establishes the foundations of what I’d like to work on for the rest of my career. 1/25 Free, full access link: rdcu.be/dbPA9
Workshop on "Measures and Representations of Interactions" looks very interesting! newton.ac.uk/event/mmvw03/ deadline to apply May 21
Happy to share our latest preprint. It’s started from failed attempts to find an effect of stroma on drug sensitivity in TNBC and made us revise our approach to chemo sensitivity assay, digging into tissue imaging&segmentation and some cool math modeling. biorxiv.org/content/10.110…
Postdoc position opening at City of Hope in ☀️☀️ California in #systemsbiology and #mathonco with a great interdisciplinary team cityofhopejobs.org/job/postdoctor…
Our preprint about differences in somatic mutation accumulation in oligodendrocytes vs. neurons in the aging human brain is out! A beautiful collaboration between @ChrisAWalsh1 and @peter_j_park labs, co-led together with @luquette_j and @sarabiz86. tinyurl.com/7a26ubmz
Check out our newest pre-print led by @cwrumstp Davis Weaver: Reinforcement Learning informs optimal treatment strategies to limit antibiotic resistance. We set out to train AI that could control a simulated E. Coli population given limited information. doi.org/10.1101/2023.0…
PhD position in Theoretical Eco-Evolutionary Dynamics (m/f/x) at the Leibniz Institute of Freshwater Ecology and Inland Fisheries, Berlin Deadline: 31 Jan 2023 karriere-igb.softgarden.io/job/26308733/P… #phdposition #mathbio
Check out MUSYC, a free online tool to quantify drug synergy: musyc.lolab.xyz i've been using this for the past few weeks and it's a great tool!
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