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Alan Chenome

@PolariCode

Alan Chenome reposted

In @Nature: Using AI and other cutting-edge techniques, the Klinge lab has captured the first near-continuous "molecular movie" of ribosome formation—revealing, frame by frame, how cells build the protein factories that make life possible. More here: rockefeller.edu/news/38513-maj…


Alan Chenome reposted

Amazing talk as always!

nobolly's tweet image. Amazing talk as always!

Alan Chenome reposted

RESULTS!!! Okay so got 12k reads (bug seems very hard to crack) but the kind folks at @plasmidsaurus.bsky.social offered to rerun. In the meantime, I'm getting some very strong blast hits for a recently discovered species, Edaphobacter flagellatus. FASTQ: drive.google.com/drive/folders/…

In the spirit of #BlueSoup and my friend Elinne, I am sequencing the Triton X-100 contaminant. Stay tuned! Big thanks to @johnowhitaker for bankrolling the plasmidsaurus run. All data will be made public and strain sharable. Yay, community science!

ATinyGreenCell's tweet image. In the spirit of #BlueSoup and my friend Elinne, I am sequencing the Triton X-100 contaminant. Stay tuned!

Big thanks to @johnowhitaker for bankrolling the plasmidsaurus run. All data will be made public and strain sharable. Yay, community science!
ATinyGreenCell's tweet image. In the spirit of #BlueSoup and my friend Elinne, I am sequencing the Triton X-100 contaminant. Stay tuned!

Big thanks to @johnowhitaker for bankrolling the plasmidsaurus run. All data will be made public and strain sharable. Yay, community science!
ATinyGreenCell's tweet image. In the spirit of #BlueSoup and my friend Elinne, I am sequencing the Triton X-100 contaminant. Stay tuned!

Big thanks to @johnowhitaker for bankrolling the plasmidsaurus run. All data will be made public and strain sharable. Yay, community science!
ATinyGreenCell's tweet image. In the spirit of #BlueSoup and my friend Elinne, I am sequencing the Triton X-100 contaminant. Stay tuned!

Big thanks to @johnowhitaker for bankrolling the plasmidsaurus run. All data will be made public and strain sharable. Yay, community science!


Alan Chenome reposted

Hybrids reveal accessible chromatin trans genetic associations biorxiv.org/content/10.110… #biorxiv_genetic


Alan Chenome reposted

New OA Article: "A single-cell rice atlas integrates multi-species data to reveal cis-regulatory evolution" rdcu.be/eHce3 Chromatin accessibility in rice & related grasses: how regulatory DNA elements evolve across cell types & species; identifying potential silencers.

NaturePlants's tweet image. New OA Article: "A single-cell rice atlas integrates multi-species data to reveal cis-regulatory evolution" rdcu.be/eHce3

Chromatin accessibility in rice & related grasses: how regulatory DNA elements evolve across cell types & species; identifying potential silencers.

Alan Chenome reposted

TrimNN paper is out at Nature Communications today. We propose the idea of Cellular Community Motifs in spatial omics and use a graph neural network approach to explore cell organization rules, deciphering the relations between structure and functions nature.com/articles/s4146…


Alan Chenome reposted

Non-catalytic and catalytic TREHALOSE-6-PHOSPHATE SYNTHASES interact with RAMOSA3 to control maize development. biorxiv.org/content/10.110… #biorxiv_plants


Alan Chenome reposted

An in planta single-cell screen to accelerate functional genetics biorxiv.org/content/10.110… #biorxiv_plants


Alan Chenome reposted

👏👍🏼 to auxotrophic Agrobacterium. 5th week of culture and no Agro overgrowth. Less antibiotics needed in selection media 🧫. Great for #undergrad labs. Will transform my plant plasmids 🧬 into these strains🦠🧪. Petunia leaf explants 🌱 expressing the RUBY 🔴 gene. #ECSU

revealplant's tweet image. 👏👍🏼 to auxotrophic Agrobacterium. 5th week of culture and no Agro overgrowth.  Less antibiotics needed in selection media 🧫.  Great for #undergrad labs.  Will transform my plant plasmids 🧬 into these strains🦠🧪.  Petunia leaf explants 🌱 expressing the RUBY 🔴 gene. #ECSU

Alan Chenome reposted

Today is my first day at @genentech in Dr. Aviv Regev's Lab. Yes, yours truly, a (plant) geneticist. In a phenomenal group pioneering lab-in-the-loop methods to accelerate drug discovery.

SessenDaniel's tweet image. Today is my first day at @genentech in Dr. Aviv Regev's Lab.
Yes, yours truly, a (plant) geneticist. In a phenomenal group pioneering lab-in-the-loop methods to accelerate drug discovery.

Alan Chenome reposted

12 years ago, I typed my first "Hello world!". It is not easy to learn bioinformatics from scratch. But it is possible if you put in effort and have a clear pathway.

tangming2005's tweet image. 12 years ago, I typed my first "Hello world!". It is not easy to learn bioinformatics from scratch. But it is possible if you put in effort and have a clear pathway.

Alan Chenome reposted

Autobioluminescence with a single, easy-to-use transcript; designed with the help of our hero, iggypop. pnas.org/doi/10.1073/pn…


Alan Chenome reposted

🚨 New preprint alert! 🚨 We used single-cell RNA-seq + GRN analysis to uncover novel morphogenic genes that boost #maize transformation frequency 🌽 biorxiv.org/content/10.110… Thanks to @plaza_genomics and all other co-authors! #PlantScience #scRNAseq

LaurensPauwels's tweet image. 🚨 New preprint alert! 🚨

We used single-cell RNA-seq + GRN analysis to uncover novel morphogenic genes that boost #maize transformation frequency 🌽

biorxiv.org/content/10.110…

Thanks to @plaza_genomics and all other co-authors!

#PlantScience #scRNAseq

Alan Chenome reposted

📢We are #hiring! 📢Please RT! @mpipz_cologne has a group leader position available in the broad area of Plant Development and Diversity. Apply now! 👉bit.ly/4nkUvLa #plantscience

mpipz_cologne's tweet image. 📢We are #hiring! 📢Please RT! @mpipz_cologne has a group leader position available in the broad area of Plant Development and Diversity. Apply now! 👉bit.ly/4nkUvLa #plantscience

Alan Chenome reposted

🚨 Science Communication #OpportunityAlert: The McClintock Letters! Federal funding for scientific research is under unprecedented threat. But how the public responds to this threat depends on the stories they hear, and who they hear them from. Direct communication is how we…

ASPB's tweet image. 🚨 Science Communication #OpportunityAlert: The McClintock Letters! Federal funding for scientific research is under unprecedented threat. But how the public responds to this threat depends on the stories they hear, and who they hear them from. Direct communication is how we…

Alan Chenome reposted

Dear maize geneticists, we are compiling missense mutations linked to visible phenotypes in maize. If you know of studies with such data, pls let us know through Twitter or email @liu3zhen@ksu.edu. Thank you! @MaizeGDB


Alan Chenome reposted

John Fowler’s guest column in the Clayton Tribune- his hometown newspaper- to provide ideas that folks could connect with, relating how federal investment in scientific research provides benefits to all Americans, including those from a small town in northeast GA. @jefowlerjr

NAASC_NA_ICAR's tweet image. John Fowler’s guest column in the Clayton Tribune- his hometown newspaper- to provide ideas that folks could connect with, relating how federal investment in scientific research provides benefits to all Americans, including those from a small town in northeast GA. @jefowlerjr

Alan Chenome reposted

Our latest paper is out in its final form in @ThePlantCell We show that in plants the same DNA sequence can act as an insulator or silencer depending on the surrounding regulatory context. Read the full paper at: doi.org/10.1093/plcell…

TobiasJores's tweet image. Our latest paper is out in its final form in
@ThePlantCell 
We show that in plants the same DNA sequence can act as an insulator or  silencer depending on the surrounding regulatory context. Read the full paper at: doi.org/10.1093/plcell…

Alan Chenome reposted

Childcare shouldn’t be a barrier to presenting your research. The ASPB Plant Biology Conference Participation Fund offers childcare subsidies, travel grants & more to help scientists attend #PlantBio2025. 💚 Give back today: bit.ly/4kQXFUP #STEMEquity #SupportScience


Alan Chenome reposted

New data from the Bob Schmitz lab (Marand 2025) on cell type-specific cis-regulation in maize! This study, in @ScienceMagazine, reveals how DNA changes impact expression and maize traits. Explore the 176 tracks on our browser (Epigenetics and DNA Binding) science.org/doi/10.1126/sc…


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