SaravanabhavanT's profile picture. Thangavel lab at CSCR, Vellore.
Gene editing. hematopoietic stem cells. Gene therapy.

Saravanabhavan Thangavel

@SaravanabhavanT

Thangavel lab at CSCR, Vellore. Gene editing. hematopoietic stem cells. Gene therapy.

In collaboration with @SrujanMare58687, we report “niche in a dish” system that eliminates the need for external cytokines during culture of hematopoietic stem cells for gene therapy applications. link.springer.com/article/10.118… @CSCR_CMC_inStem @DBT_inStem @DBTIndia @OffCMCVellore


Saravanabhavan Thangavel reposted

Proper contingent at the 13th Conclave @India_Alliance 2025. Fellows: @abimaneshID, @rohan_mic, @MahasampathG, Poonguzhali B; Team Science: Arul P Lionel, @SaravanabhavanT, Mohan Kumar Murugesan @CSCR_CMC_inStem; CRC&CRTP: Respind-Net @mahesh_moorthy -among others @OffCMCVellore

mahesh_moorthy's tweet image. Proper contingent at the 13th Conclave @India_Alliance  2025. Fellows: @abimaneshID, @rohan_mic, @MahasampathG, Poonguzhali B; Team Science: Arul P Lionel, @SaravanabhavanT, Mohan Kumar Murugesan @CSCR_CMC_inStem; CRC&CRTP: Respind-Net @mahesh_moorthy -among others @OffCMCVellore

Saravanabhavan Thangavel reposted

To introduce new medical students at @OffCMCVellore to the latest in regenerative medicine and genetic treatments @MohankumarKMur1 & @SaravanabhavanT shared insights on cell & gene therapy research highlighting breakthroughs at @CSCR_CMC_inStem @DBT_inStem @DBTIndia #GeneTherapy

CSCR_CMC_inStem's tweet image. To introduce new medical students at @OffCMCVellore to the latest in regenerative medicine and genetic treatments @MohankumarKMur1 & @SaravanabhavanT shared insights on cell & gene therapy research highlighting breakthroughs at @CSCR_CMC_inStem @DBT_inStem @DBTIndia
#GeneTherapy
CSCR_CMC_inStem's tweet image. To introduce new medical students at @OffCMCVellore to the latest in regenerative medicine and genetic treatments @MohankumarKMur1 & @SaravanabhavanT shared insights on cell & gene therapy research highlighting breakthroughs at @CSCR_CMC_inStem @DBT_inStem @DBTIndia
#GeneTherapy

New publication from our lab showing therapeutic dual-beneficial mutations gene editing for the gene therapy of sickle cell disease and β-thalassemia. stemcellres.biomedcentral.com/articles/10.11… @DBTIndia @CSCR_CMC_inStem @DBT_inStem @OffCMCVellore @Prathibhapbc #SickleCellDisease #GeneTherapy

SaravanabhavanT's tweet image. New publication from our lab showing therapeutic dual-beneficial mutations gene editing for the gene therapy of sickle cell disease and β-thalassemia.
stemcellres.biomedcentral.com/articles/10.11…
@DBTIndia @CSCR_CMC_inStem @DBT_inStem @OffCMCVellore @Prathibhapbc
#SickleCellDisease #GeneTherapy

Proud moment for us at @CSCR_CMC_inStem !

The Hindu: Indian scientists develop novel gene therapy for haemophilia Department of Biotechnology #DBT, Ministry of Science and Technology, Government of India Read: thehindu.com/sci-tech/healt…

DrJitendraSingh's tweet image. The Hindu: Indian scientists develop novel gene therapy for haemophilia
Department of Biotechnology #DBT, Ministry of Science and Technology, Government of India

Read:
thehindu.com/sci-tech/healt…


Read our commentary rdcu.be/dVl59 on the new findings on HSPCs from Mikkola's lab & potential improvements this can bring to the hematopoietic stem cell and gene therapy. Congratulations @Prathibhapbc #genetherapy #stemcells @CSCR_CMC_inStem @DBT_inStem @DBTIndia


Saravanabhavan Thangavel reposted

🎊🎉Congratulation to Dr. @SrujanMare58687  for joining the editorial board of Discover Nano-SpringerLink Journal @Discover_Jrnls #nanodiscovery #editorialship #discovernano

CSCR_CMC_inStem's tweet image. 🎊🎉Congratulation to Dr. @SrujanMare58687  for joining the editorial board of Discover Nano-SpringerLink Journal @Discover_Jrnls
#nanodiscovery #editorialship #discovernano

Saravanabhavan Thangavel reposted

Student Talk #ARR2024 Day 2 Chemical Technology Session @Prathibhapbc of @SaravanabhavanT Lab spoke on "Editing the HBG promoter in hematopoietic stem and progenitor cells through homology-directed repair for β-hemoglobinopathies treatment" + Q&A @CSCR_CMC_inStem @DBTIndia

DBT_inStem's tweet image. Student Talk #ARR2024
Day 2 Chemical Technology Session
@Prathibhapbc of @SaravanabhavanT Lab spoke on "Editing the HBG promoter in hematopoietic stem and progenitor cells through homology-directed repair for β-hemoglobinopathies treatment"  + Q&A
@CSCR_CMC_inStem 
@DBTIndia
DBT_inStem's tweet image. Student Talk #ARR2024
Day 2 Chemical Technology Session
@Prathibhapbc of @SaravanabhavanT Lab spoke on "Editing the HBG promoter in hematopoietic stem and progenitor cells through homology-directed repair for β-hemoglobinopathies treatment"  + Q&A
@CSCR_CMC_inStem 
@DBTIndia
DBT_inStem's tweet image. Student Talk #ARR2024
Day 2 Chemical Technology Session
@Prathibhapbc of @SaravanabhavanT Lab spoke on "Editing the HBG promoter in hematopoietic stem and progenitor cells through homology-directed repair for β-hemoglobinopathies treatment"  + Q&A
@CSCR_CMC_inStem 
@DBTIndia

Saravanabhavan Thangavel reposted

#ARR2024 Day 2 Session Molecular Basis of Disease - Part III Dr Sarvanabhavan Thangavel of our vellore unit @CSCR_CMC_inStem spoke on “Gene-edited hematopoietic stem and progenitor cells for gene therapy for Beta-hemoglobinopathies” An engaging Q&A followed @DBTIndia

DBT_inStem's tweet image. #ARR2024
Day 2 Session Molecular Basis of Disease - Part III 
Dr Sarvanabhavan Thangavel of our vellore unit @CSCR_CMC_inStem spoke on “Gene-edited hematopoietic stem and progenitor cells for gene therapy for Beta-hemoglobinopathies” 
An engaging Q&A followed
@DBTIndia
DBT_inStem's tweet image. #ARR2024
Day 2 Session Molecular Basis of Disease - Part III 
Dr Sarvanabhavan Thangavel of our vellore unit @CSCR_CMC_inStem spoke on “Gene-edited hematopoietic stem and progenitor cells for gene therapy for Beta-hemoglobinopathies” 
An engaging Q&A followed
@DBTIndia
DBT_inStem's tweet image. #ARR2024
Day 2 Session Molecular Basis of Disease - Part III 
Dr Sarvanabhavan Thangavel of our vellore unit @CSCR_CMC_inStem spoke on “Gene-edited hematopoietic stem and progenitor cells for gene therapy for Beta-hemoglobinopathies” 
An engaging Q&A followed
@DBTIndia
DBT_inStem's tweet image. #ARR2024
Day 2 Session Molecular Basis of Disease - Part III 
Dr Sarvanabhavan Thangavel of our vellore unit @CSCR_CMC_inStem spoke on “Gene-edited hematopoietic stem and progenitor cells for gene therapy for Beta-hemoglobinopathies” 
An engaging Q&A followed
@DBTIndia

Our group is hiring for JRF and technician positions to work on gene editing. Apply at cscr.res.in/research-oppor… or contact me. Application deadline: March 25, 2024.


Next-gen mRNA vaccine with indigenous LNPs! Congratulations @SrujanMare58687 for this beautiful work! Our contribution was to demonstrate the M2-macrophage-specific delivery of mRNAs by LNPs. @karthikvk1996. #mRNA #LNPs @CSCR_CMC_inStem @DBT_inStem @OffCMCVellore @DBTIndia

Dendritic cell targeting SMART-lipid nanoparticles enabled mRNA vaccine elicits cross-reactive humoral responses against the omicron sub-variants dlvr.it/T3Mk6n #genetherapy #celltherapy



What a great way to start the year! Vigneshwaran @vigneshvnkt from our lab, was awarded the Sun Pharma Science Foundation's Science Scholar Award for 2023.  Congratulations Vignesh! We are very proud of you! @SunPharma_Live @DBTIndia @DBT_inStem @CSCR_CMC_inStem @OffCMCVellore

We are excited to announce the winners of Sun Pharma Science Foundation’s ‘Science Scholar Awards’ 2023. We hope this recognition encourages these young minds to pursue research as a career and commit themselves towards the advancement of science. #ReachingPeopleTouchingLives



Registration for our 8th annual cell and gene therapy symposium is now open! Important topics and a fascinating lineup of speakers!! #genetherapy #celltherapy @CSCR_CMC_inStem @DBT_inStem

SaravanabhavanT's tweet image. Registration for our 8th annual cell and gene therapy symposium is now open!
Important topics and a fascinating lineup of speakers!!
#genetherapy #celltherapy
@CSCR_CMC_inStem @DBT_inStem

Our work on gene editing therapy for Beta-hemoglobinopathies is on the cover of @moltherapy #WorldSickleCellDay @DBTIndia @DBT_inStem @CSCR_CMC_inStem @redglobin @Prathibhapbc

New issue of @MolTherapy Nucleic Acids (#MTNA) out today! On the cover: A schematic illustration of a novel #geneediting strategy for #genetherapy for Beta-hemoglobinopathies. ow.ly/zgjK50ONnfK

MolTherapy's tweet image. New issue of @MolTherapy Nucleic Acids (#MTNA) out today! On the cover: A schematic illustration of a novel #geneediting strategy for #genetherapy for Beta-hemoglobinopathies. ow.ly/zgjK50ONnfK


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