Scanlan Group TCD
@ScanlanGroupTCD
Twitter of the Biomolecular and Bioconjugate Synthesis Group, School of Chemistry, Trinity College Dublin @TCD_Chemistry. Account managed by group members.
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This week, the Scanlan Group attended Chemical Biology Ireland 2024. A huge thank you to all of the organizers, particularly Eddie Myers. Congratulations to @laura_ramireez as well for winning a poster prize and Alby Benny for his brilliant talk!
Check out the Scanlan Group's latest publication by Alby Benny about the photochemical macrocyclisation of thiolactone peptides via acyl thiol-ene. 💡💡💡 doi.org/10.1039/D4CC02…
Such a pleasure to be one of the poster winners! Lovely conference, it was great to meet so many new people and hear about exciting research in Chemical Biology 🥰
End to a great conference in Galway with the Poster winners, congratulations! Congratulations and thanks to Eddie Myers, Marina Rubin’s, and Eddie’s research group for all their efforts @irishchemistry @uniofgalway
Thanks to our favourite supplier @Fluorochem for the goodie bag!! Including the best balloons in the business🎈🎈🎈 #inertreactionsincoming
🔥 NEW PAPER 🔥 Lynch and Nolan et al. (2023), “Traceless Thioacid-Mediated Radical Cyclization of 1,6-Dienes” So glad this is finally online in @JOC_OL - huge thanks to all my co-authors and especially @markpnolan ! pubs.acs.org/doi/10.1021/ac… #Chemistry #Radicals
Congratulations to our 3rd year PhD students - Alby, @markpnolan, @MissGlenna_1 & @laura_ramireez - who all presented in @ucddublin yesterday. A special well done to Alby Benny for earning an @EliLillyandCo speaker prize!
I’m pleased to share our latest work on high-throughput thiol-ene chemistry, now published in Peptide Science (Open Access)! onlinelibrary.wiley.com/doi/10.1002/pe…
Ready to get your chemical signals active (In more ways than one)? 🧠 Next week we have our pub quiz night which will be held in Wigwam ✨ TEAM SIGN-UPS ARE AVAILABLE ON OUR LINKTREE (Link in our bio)! Remember, if you lose, blame it on the CH₃−CH₂−OH 🍻
What a great effort by @Harlei_Martin @laura_ramireez @ScanlanGroupTCD on this fantastic review (open access) just out doi.org/10.1039/D2CS00… in @ChemSocRev on enzymatic triggered drug release from glyco-conjugated prodrugs! @SSPCentre @IrishResearch @TCD_Chemistry
Check out our new paper with @ThorriGunnlaugs @Harlei_Martin @laura_ramireez in @ChemSocRev "Glycosidase activated prodrugs for targeted cancer therapy"👩🔬🧪💊 doi.org/10.1039/D2CS00… @TCD_Chemistry @tcdTBSI @SSPCentre @IrishResearch @scienceirel #loveirishresearch
Excellent talk on enzyme activated molecular probes by my former colleague @TCD_Chemistry and collaborator @ScanlanGroupTCD at @msmlg2020 today! 👏
Our latest paper is out, performing Green bioconjugation using Thiol-Ene Click in Deep Eutectic Solvents! @RoySocChem @green_rsc @TCD_Chemistry @tcdTBSI @SSPCentre @scienceirel
End to a great conference in Galway with the Poster winners, congratulations! Congratulations and thanks to Eddie Myers, Marina Rubin’s, and Eddie’s research group for all their efforts @irishchemistry @uniofgalway
See one of our latest papers below, which details how a cytotoxic drug can be enzymatically released and monitored in real time - which provided a unique insight into the pharmacokinetic profile! #Pharmacokinetics #Amonafide #Glycotime #Carbohydrates
🔥 NEW PAPER! 🔥 Glad to finally see our work on glycosylated prodrugs online. A fantastic collaboration between multiple research groups. Want to see how I finally got to work with phosgene? Follow the DOI: doi.org/10.1002/chem.2… #IrishResearch #Glycoscience #Prodrug #ChemEurJ
Check out our new paper in @ChemSocRev, "Cysteinyl radicals in chemical synthesis and in nature" @RoySocChem @TCD_Chemistry #RadicalChemistry #PeptideChemistry #CysteineChapel pubs.rsc.org/en/content/art…
pubs.rsc.org
Cysteinyl radicals in chemical synthesis and in nature
Nature harnesses the unique properties of cysteinyl radical intermediates for a diverse range of essential biological transformations including DNA biosynthesis and repair, metabolism, and biological...
Radical-Mediated Acyl Thiol-Ene Reaction for Rapid Synthesis of Biomolecular Thioester Derivatives by Eoin M. Scanlan and co-workers (@ScanlanGroupTCD, @TCD_Chemistry) onlinelibrary.wiley.com/doi/10.1002/ej…
New paper from the group available online now! #ThiolEne #SulfurRadicals #Bioconjugation #RadicalChemistry
🔥🚨NEW PAPER ALERT🚨🔥 So excited to finally share this one from @ScanlanGroupTCD ! Using sulfur radicals and acyl shifts to synthesis biomolecular derivatives - check below to read the full account! ⤵️⤵️⤵️ doi.org/10.1002/ejoc.2… #IrishResearch #RadicalChemistry #Bioconjugate
Congrats @KatieBowen_ for her latest publication on the membrane intramolecular transacylase reaction! See below👇 🔥 #IrishResearch #Lipoprotein nature.com/articles/s4146…
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