Science of NAD
@ScienceOfNAD
A great place to keep track of the emerging science of NAD replenishment, organizing hundreds of research studies. [email protected]
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Oral NR treatment at 3000 mg daily for 4 weeks was safe, and NR even at a dose of 3000 mg for 4 weeks did not cause depletion of the methyl-group pool nature.com/articles/s4146…
Nicotinamide riboside alleviates persistent pain in mice newscientist.com/article/240140…
Patients with the rare metabolic disorder Arts Syndrome appear to have clinical improvement with SAMe and nicotinamide riboside onlinelibrary.wiley.com/doi/pdf/10.100…
Radiation: Mouse study shows NR's potential to be a therapeutic agent for delayed effects of acute radiation exposure in patients receiving radiotherapy and exposed populations onlinelibrary.wiley.com/doi/10.1111/ac…
onlinelibrary.wiley.com
Nicotinamide riboside intervention alleviates hematopoietic system injury of ionizing radiation‐i...
The premature aging mice of delayed effects of acute radiation exposure (DEARE) model is established after 6 Gy total body irradiation. Nicotinamide riboside assists senescent spleen recovery in...
🔬 Curious about cellular health and nicotinamide riboside? 🔬Participate in an insightful AMA with @CharlesMBrenner on the r/nicotinamideriboside subreddit. Ask your burning questions about Tru Niagen and discover how it supports your vitality. Join the conversation!
It has been more than two years since scientists told us that vitamin B3 could treat sepsis. Since then, we have helped a lot of septic rodents. Now the CDC is trying to take sepsis more seriously. scienceofnad.com/post/sepsis-an…
.@CharlesMBrenner is hosting an AMA Q&A at the NR subreddit. Lots of great questions already: reddit.com/r/Nicotinamide…
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From the NicotinamideRiboside community on Reddit
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Dr. Charles Brenner answers your questions live on Reddit, Monday September 4, 10am Pacific, at reddit.com/r/Nicotinamide…
NR supplementation blunts Th1 and Th17 immune responsiveness in healthy volunteers and in psoriasis. The concept is now being explored in vivo, where mild to moderate psoriasis patients are being investigated in a placebo-controlled study. https:// cell.com/cell-reports-m…
Meta-analyses of 29 random controlled trials with 8,664 participants indicated a significant reduction in systolic and diastolic blood pressure for the NAD+ precursors supplementation compared with the control group. onlinelibrary.wiley.com/doi/10.1111/ec…
onlinelibrary.wiley.com
Effects of NAD+ precursors on blood pressure, C‐reactive protein concentration and carotid intima...
There are contradictory effects regarding the effect of NAD+ precursor on blood pressure and inflammation. Results from meta-analyses of RCTs from random-effects models indicated a significant...
Stem Cells: NAD+ metabolism governs the anti-inflammatory function of mesenchymal stem cells during inflammation nature.com/articles/s4142…
Preprint: "The evidence that psoriasis lesions show NADH/NAD+ redox imbalance towards oxidation may have important therapeutic implications....Increasing the level of NAD+ in psoriatic lesions could be considered as a therapeutic option..." researchgate.net/publication/37…
Diabetes: NR supplementation boosted NAD metabolism to augment mitochondrial function, reducing inflammation and thereby preventing progression of diabetic kidney disease in mice reddit.com/r/Nicotinamide…
"We have demonstrated a time-of-day dependent response to NAD+ therapy." Clinical trials that report conflicting results from NAD treatment mostly overlook the time of drug intake. Proposed: time of treatment dictates the amplitude of metabolic benefits. reddit.com/r/Nicotinamide…
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