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Sebastian Brandner

@Seb_Brandner

Sebastian Brandner reposted

Beautiful!


Discovery of drug response in IDH mutant gliomas with a potential to treat astrocytomas and oligodendrogliomas. cancerres.aacrjournals.org/content/early/… Very pleased that this has just been published in CANCER RESEARCH. Will be in Pubmed soon.

Seb_Brandner's tweet image. Discovery of drug response in IDH mutant gliomas with a potential to treat astrocytomas and oligodendrogliomas. 
cancerres.aacrjournals.org/content/early/… 
Very pleased that this has just been published in CANCER RESEARCH. Will be in Pubmed soon.

Mutant IDH sensitizes gliomas to endoplasmic reticulum stress and triggers apoptosis by MicroRNA183-mediated inhibition of Semaphorin 3E cancerres.aacrjournals.org/content/early/…


Methylation array profiling of adult brain tumours: diagnostic outcomes in a large, single centre app.peer.us/papers/public/…


I think it may be more common than previously thought. Just need to observe carefully and connect the facts.

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Indeed, important and groundbreaking finding that change the view on transmissible proteopathies

Zane Jaunmuktane speaking now about abeta transmissibility - one of the most exciting new observations in CAA in recent years #ICAA18 @UCLBrainScience



nature.com/articles/s4138… Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades


rdcu.be/NGwB: GPR 158 and miR-449 as new brain tumour malignancy bio-markers and possible therapeutic targets


It was an interesting and engaging event. Well done!

Testing our histological diagnosis skills with @Seb_Brandner at @EU_Brain #BrainMissionFP9

mtvc2's tweet image. Testing our histological diagnosis skills with @Seb_Brandner at @EU_Brain #BrainMissionFP9


nature.com/articles/s4138… Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades: Possible new therapeutic target and biomarker.


Sebastian Brandner reposted

Inhibition of GPR158 by microRNA449a suppresses neural lineage of glioma stemprogenitor null tinyurl.com/y7q26nw3 #DTHSTR


Sebastian Brandner reposted

#stem_cells_GBM_papers / #miRNA_GBM_papers: Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades Oncogene 2018 rdcu.be/NpaA


Sebastian Brandner reposted

Inhibition of GPR158 by microRNA-449a suppresses neural lineage of glioma stem/progenitor cells and correlates with higher glioma grades. ift.tt/2rjVMXS #Neuralstemcells


Next step: to update with new subclasses.


We are not changing that much actually. Of 400 tumours in our lab, we changed diagnosis on 20%. And these 400 are a 10% selection already. So, no worries we'll stick with WHO 2016 for most tumours for a while


that was two years ago.


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