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Our Dr. Sachet Shukla is hopeful about the potential of personalized cancer vaccines. “I think you’ll see another step jump in the accuracy of these algorithms,” he says. Learn more: brnw.ch/21wKHqL @Nature @ShuklaSachet #EndCancer
1/ 🧵Excited to share our latest study published in @NatureCancer co-led with amazing co-first authors and friends @TJammihal and @ChrisLabaki under the exceptional mentorship of @DrChoueiri @BraunMDPhD @ShuklaSachet nature.com/articles/s4301…
Great story in @Nature by @ElieDolgin on the promise and potential of personalized cancer vaccines. Thanks to Elie for making us a part of this discussion! nature.com/articles/d4158…
nature.com
How personalized cancer vaccines could keep tumours from coming back
Nature - The same mRNA technology that quickly brought the world a vaccine for COVID-19 is now showing promise as a bespoke therapy for cancer.
Dr. Sachet Shukla is a new GSBS faculty affiliated with the Immunology and QS Programs. He led a successful translational immunogenomics group at Dana-Farber before joining MDA in Nov 2021. He is looking for PhD students and postdocs interested in exciting translational projects!
Very grateful to @KidneyCancer for the award, and to the amazing team (@Chrislabaki1 @LisaHenske @shuklasachet @VanAllenLab @DrChoueiri and others) as we try to better understand and treat this histology and beyond @YaleCancer @SmilowCancer
⭐️Congratulations to KCA Trailblazer Award winner @BraunMDPhD @YaleCancer @YaleMed! His research will dissect the #immunobiology of #chromophobe #RCC using single-cell transcriptomics. #kidneycancer kidneycancer.org/2022-grants/
Thankful to @abc7newsbayarea for the invitation to share my views on the relevance and timeliness of cancer vaccines. Live/streaming interview with @abc7kristensze on Oct 11th 2022 (first 10min at the link below): facebook.com/abc7news/video…
Good morning! You've been asking -- here you go! #KCRS22 Video & Slides are up! · Video · Slides · Abstracts · Posters ➡️ bit.ly/WatchKCRS22 * Some slides/video are removed at the author's request. We will add when able. @OncoAlert @OncLive @TargetedOnc @IKCCorg
🚨Hot off the press in @NatureMedicine👉After KRAS G12C going after the next undruggable-KRAS G12D👉Anti-tumor efficacy of a potent & selective non-covalent KRAS G12D inhibitor 🎯🧬Huge implications in #precisionmedicine if translated to clinic @oncoalert go.nature.com/3ExqaoJ
Maybe cancers can be intercepted. Vaccine studies offer hope nytimes.com/2022/10/10/hea…
Great piece by @ginakolata in NYT today about cancer vaccines. Preventive/early use of vaccines will be paradigm-shifting in the coming years. Grateful to be part of this story! nytimes.com/2022/10/10/hea…
I can't thank you enough for giving me the opportunity to present this work (and for everything)
Extremely grateful for the exceptional guidance of my mentors @BraunMDPhD @VanAllenLab @DrChoueiri , the collaboration with renowned scientists @LisaHenske @ShuklaSachet , and the help from all team members in this project. This work would not have been possible without them.
Why chromophobe RCC is not immune-responsive? @Chrislabaki1 is tackling this problem in a brilliant way !!!
Why chromophobe RCC is not immune-responsive? @Chrislabaki1 is tackling this problem in a brilliant way !!!
First single-cell look at infiltrating immune cells in benign -> malignant renal oncocytic neoplasms jointly with #LisaHenske @BraunMDPhD @DrChoueiri @VanAllenLab led by @Chrislabaki1. Takeaway: less infiltrated, exhausted, non-specific T-cells in these tumors
@Chrislabaki1 doing great microenvironment work @DanaFarber_GU in chromophobe #kidneycancer. #KCRS22 @kidneycan
Validation of RNA subgroups @brian_rini and response data with axi/avelumab @ReneeSaliby #kcrs22.Distribution across groups were the same as IM151. But axi/avelumab was better across all groups-unlike atezo/bev. Response within groups will be regimen specific
@Chrislabaki1 doing great microenvironment work @DanaFarber_GU in chromophobe #kidneycancer. #KCRS22 @kidneycan
We take this pic every year at #KCRS, and this year, we had to switch up locations to accommodate our growing group of folks working to #acceleratecures for #kidneycancer. What an incredible honor to bring all these brains together! #KCRS22 @OncoAlert
Dr @ReneeSaliby super star @DanaFarber_GU knocking it out of the park with her work with the molecular clusters in mRCC! Bravo! #KCRS22 @BraunMDPhD @ShuklaSachet @VanAllenLab #WCRM
These 3 set the bar really high for oral presentations! Super happy to see our work masterfully presented by @TJammihal #KCRS22 @kidneycan @OncoAlert
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