The Piston Lab
@ThePistonLab
Piston Lab focuses on glucagon regulation and uses innovative quantitative imaging and biochemical methods to identify new therapeutic targets for diabetes
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I’m excited to share that my thesis work on brown adipocyte-secreted proteins and their role in regulating Type 1 Diabetes is now published! Huge thanks to @ThePistonLab and collaborators! diabetesjournals.org/diabetes/artic…
Our undergraduate student - Jeremy Cho, presenting his poster at the @washuartsci undergraduate Research Symposium! 👨🔬
The potential role of basement membrane protein #Nidogen-2 in the management of #TypelDiabetes has been explored by @ThePistonLab. Check out our latest preprint!
Insulin-Independent Regulation of Type 1 Diabetes via Brown Adipocyte-Secreted Proteins and the Novel Glucagon Regulator Nidogen-2. biorxiv.org/cgi/content/sh… #biorxiv_cellbio
Our one-day symposium at #EASD2024 on September 9th, 2024, in Madrid, Spain is next week! This event will include a session on “Understanding and restoring alpha cell function in T1D and T2D: intrinsic, paracrine, and in vivo consequences in humans.” This session will be…
A bit late, but I'm thrilled to share that I successfully defended my PhD on July 30th! It’s been an incredible journey, and I’m so grateful for all the support along the way, especially @ThePistonLab 🎓
Happy to share our recent paper using fluctuation spectroscopy to reveal that G protein-coupled receptors appear to interact only transiently with their Gα and Gβγ protein subunits - not by pre-assembled complexes. authors.elsevier.com/a/1je-l1SPT7tAM
🌸 Marching into a new month with a spring in our step. 🌼
Great job Farzad!
Data suggests that targeting the α cell EphA4 receptor by sustained release of WCDD301 is a promising pharmacologic pathway for suppressing glucagon and normalizing hyperglycemia in patients with #T1D insight.jci.org/articles/view/…
A new paper from the lab: Focused on understanding how beta-cells modify their NADPH metabolism to deal with stress, we translated our genetically encoded Apollo-NADP+sensor to living #Zebrafish. science.org/doi/10.1126/sc…
Program Officer Ben Williams welcomed researchers from the Alpha Cell Scientific Working Group to a scientific meeting in Edinburgh, Scotland. This group of Helmsley grantees aims to better understand pancreatic alpha cells and develop therapeutic strategies to prevent…
Happy to share that I've been awarded The David and Deborah Winston Fellowship in Diabetes Research!✨ Even more special is the fact that our cat lady @MandyMChan, is also a fellow recipient! 🎉Grateful for this opportunity and looking forward to making the most of it! :)
4 years ago, I began working with other PhD researchers develop a program to help ALL underrepresented students strategically for STEM PhD applications. The program has helped 443 students matriculate into graduate programs. Read our strategy and recommendations here ⬇️⬇️
Out now in @CellCellPress! doi.org/10.1016/j.cell… Historically marginalized student representation drastically drops from undergrad to grad school. Are underrepresented students unqualified? Or are grad school admissions unnecessarily confusing, costly, & gatekeeping? 1/🧵
NIH funding by institution for FY 2023 1 Johns Hopkins U $518M 2 UCSF $451M 3 U Michigan $436M 4 Penn $434M 5 UCLA $424M 6 Stanford $407M 7 Mass General $406M 8 Wash U. $404M 9 Yale $390M 10 Pitt $382M 11 Columbia $362M 12 Duke $360M
🔬Welcome to ADA's 83rd Scientific Sessions, where we'll be showcasing the latest and greatest in #diabetes science and research! 🧬Get ready for an exciting few days ahead. #ADA2023
Last year, I was fortunate to attend and learn some inspiring research at the KDA symposium in Korea. Now, in 2023, I'm excited for more fascinating discoveries at the ADA 83rd scientific session! Visit my poster on Sunday to learn and discuss about my project ☺️ #ADA2023
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