Convergent Science Virtual Cancer Center
@_CSVCC
The CSVCC is a convergent approach to cancer research that combines advances from diverse scientific disciplines to improve outcomes for patients.
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Thrilled to feature Scholar, Dr. Nilay Sethi, on his new work shows how reprogramming tumors, forcing them to “grow up,” could transform colorectal cancer treatment. #ColorectalCancer #CancerResearch 🔗 blog.dana-farber.org/insight/2025/1…
Thrilled to highlight Dr. Kun-Hsing Yu whose team helped develop the groundbreaking “CHIEF” AI model — trained on 15 million pathology images across 19 cancer types. #Cancerdetection #AIinMedicine #Pathology Read more here: managedhealthcareexecutive.com/view/ai-turns-…
A @UAZCancer researcher received a $1.7M grant to continue the Convergent Science Virtual Cancer Center, with the University of Southern California, training researchers to address cancer risks in military communities. More: tinyurl.com/4nsxvp9r
We are excited to welcome seven new Scholars to the CSVCC! Each of them brings valuable expertise and perspectives that will strengthen our convergent science community. To learn more about our Scholars and the work of the CSVCC, visit csvcc.org.
Our work on Macrophages and Breast cancer brain metastasis is finally out @PNASNews doi.org/10.1073/pnas.2… Thanks editors,reviewers, and all authors.
I am looking forward to presenting a short talk on our work on macrophage ontogeny at the @ISEHSociety annual meeting.
A great collaboration with my friend @JunQiLab. We screened a small molecule library targeting epigenetic regulators curated by Jun’s team using our dual reporter system. The ensuing mechanistic work required innovative chemical and rigorous molecular biology.
Proof-of-concept: Epigenetic reprogramming could one day be a new therapeutic path in colorectal cancer. @Nilay_Sethi explains how histone acetylation shapes CRC cell fate in this @AGA_Gastro study: bit.ly/46gS7z1
Disrupting cell communication in glioblastoma— @PeiwenChen9 and team @ClevelandClinic discover GPNMB mediates bidirectional communication between GBM stem cells and tumor-associated macrophages and microglia: insight.jci.org/articles/view/…
Improving immunotherapy in glioblastoma! @PeiwenChen9 & team @ClevelandClinic discover targeting legumain—which promotes infiltration of tumor-associated macrophages via the GSK3β/STAT3 pathway—has anti-tumor effects and improves immunotherapy in preclinical GBM models:…
Happy to share our work out at @jclinicalinvest We identified a new tumor-macrophage interaction contributing to GBM progression/immunosuppression and found that targeting the symbiosis sensitizes GBM to immunotherapy. Huge thanks to editors and reviewers. jci.org/articles/view/…
Connecting the dots for the future of cancer research! This year’s CSVCC ACERT Workshop brought together insightful talks, tours, and hands-on whiteboarding sessions. Grateful to all who contributed their expertise and ideas! #convergentscience #scholars #cancer #militaryhealth
Congratulations to Scholar, @MaayanLevy_Lab!
We are thrilled to announce the recipients of the 2025 Vilcek Foundation Prizes, awarded to outstanding immigrant professionals in the arts and sciences. This year, we honored 14 prizewinners with a total of $950,000 in awards––our largest cohort yet! Read about our prizewinners…
Here's a new preprint from our group. This manuscript continues our efforts to understand the mechanisms that distinguish fetal/juvenile versus adult hematopoiesis to better understand pediatric blood diseases. biorxiv.org/content/10.110…
New research finds that a ketogenic diet enhances CAR T Cell antitumor function via β-Hydroxybutyrate ft. @Shan_Liu_, @MaayanLevy_Lab (@PennMicro), @PuneethGuru_ (@PennMedicine), @MarcoRuella & Elise Chong (@PennCancer) tinyurl.com/4tw6eddy
Congratulations on the move to Stanford!
Excited to announce our move to Stanford and the Arc Institute! We're hiring postdocs to explore the interplay between immune cells, metabolites and the microbiome in cancer, inflammation and metabolism. Apply here: postdocs.stanford.edu/prospective/op… #Postdoc #Stanford #ArcInstitute
Just in time for #ASH24, our latest is online: nature.com/articles/s4159…
Excited to share our review: “Immunotherapy for GBM: current state, challenges, and future perspectives ", just published in @Cellular & Molecular Immunology rdcu.be/dW19V
Excited to share our paper just accepted by @jclinicalinvest. We reveal a new macrophage-microglia interplay in GBM and develop a powerful therapeutic approach targeting them. jci.org/articles/view/…
Here is our latest paper now online @LeukemiaJnl. nature.com/articles/s4137…
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