Aaron Jeffries
@aaron_r_j
Sequencing and analysis of transcriptomes, genomes, epigenomes...
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Long reads @nanopore @PacBio can provide insights into epigenetics. We (@fuyilei96 @timp0) summarize the latest #Bioinformatics approaches to analyze methylation & why this matters! Out now @NatureRevGenet bit.ly/4cjxUtl @BCM_HGSC @bcmgenetics @RiceCompSci @JohnsHopkins
Join us at The Festival of Genomics & Biodata in London on Wednesday 29th - Thursday 30th January 2025, for the UK's largest gathering in the field of life sciences. @FoGenomics
Are you passionate about biophysics and curious about the origin of life? Join our group on a 3 year project funded by the Gordon and Betty Moore Foundation with Tom Richards @UniofOxford and @ju_morimoto @aberdeenuni jobs.ac.uk/job/DLB893/pos…
Really looking forward to speaking at this event next year!
Excited to announce our keynote speakers for #ECD25 12-14 March 2025 Wellcome Genome Campus UK: Edith Heard (@EMBL @TheCrick), Jonathan Mill (@PsyEpigenetics) and Xiaowei Zhuang (@Harvard) Register here: bit.ly/3Da3AEd #Epigenomics #SingleCell #Epidemiology @eventsWCS
Register now to join me at The Festival of Genomics & Biodata next month. Curious? Let me know what questions you’d love me to answer in my session. Registration is free for over 90% of the audience, click here to reserve your space: hubs.la/Q02TptWZ0 #FOG2025
HUGE congratulations to @rbamford5 who received a ASHG Research Excellence Trainee award at #ASHG24 #ASHG2024. What an amazing achievement! @UniofExeter @uniofexeHLS @ExeterNeuro @ExeterBRC
ASHG Trainee Research Excellence Post-Doctoral Winners also accepted their awards during #ASHG24! 🏆Rosemary Bamford (@UniofExeter) 🏆Johanna Smith (@MayoClinic) 🏆 Giovanni Quinones-Valdez (@UofCalifornia) Congratulations everyone! 🎊
Super proud of @rbamford5 (Rosie Bamford) who is a finalist for the @GeneticsSociety ASHG Training Research Excellence Award. If you are at the meeting and interested in brain alternative splicing, make sure you check out her talk! #ASHG24 #ASHG2024 @UniofExeterNews @uniofexeHLS
ASHG Trainee Research Excellence Post-Doctoral Winners also accepted their awards during #ASHG24! 🏆Rosemary Bamford (@UniofExeter) 🏆Johanna Smith (@MayoClinic) 🏆 Giovanni Quinones-Valdez (@UofCalifornia) Congratulations everyone! 🎊
We are looking for a bioinformatician to support our #illumina #nanopore sequencing work and #olinkproteomics at @uniofexeHLS. Please see the link below for more info.
Recruiting now for a DNA Sequencing Bioinformatician, to maintain, develop and use computational pipelines for the Sequencing Facility. To find out more: ow.ly/ruyQ50SSTj9
Have you ever wondered which single cell/spatial omic technology to use? Excited to share the scTrends Consortium's first report on single-cell and spatial genomics tech! Check out our comment in @NatureBiotech! #Genomics #Biotech #scTrends nature.com/articles/s4158…
It is great to see this work out @PLOSPathogens showing that a Burkholderia #phage boosts #antibiotic efficacy by decreasing #efflux. Great collaborative work with @KrasiTsaneva @mark_blaskovich @IMBatUQ @dstlmod @MahidolU doi.org/10.1371/journa…
What if we could universally recombine, insert, delete, or invert any two pieces of DNA? In back-to-back @Nature papers, we report the discovery of bridge RNAs and 3 atomic structures of the first natural RNA-guided recombinase - a new mechanism for programmable genome design
Thrilled to share my (first) first author paper ‘Developmentally dynamic changes in DNA methylation in the human pancreas’ @PsyEpigenetics @UofE_Research @Exeter_Diabetes bmcgenomics.biomedcentral.com/articles/10.11… (1/)
A position is available at the University of Exeter Sequencing Facility to join our team and work with the latest technology from #illumina and #nanopore
OPPORTUNITY: Technician (Exeter Sequencing Facility), grade D, closing date 28/05. Join a busy lab and dynamic team environment and support the sequencing facility to help deliver sequencing projects for internal and external researchers. jobs.exeter.ac.uk/hrpr_webrecrui…
A presentation by Illumina $ILMN on the XLEAP-SBS. It all started 25 years ago in Cambridge UK (Solexa).
We are hosting the South of England Genetic Epidemiology Group (SEGEG) meeting at the University of Exeter on July 1st! Registration is free and now open - forms.office.com/e/tengc4eKLk
forms.office.com
Microsoft Forms
Microsoft Forms
The difference in @10xGenomics' Cell Ranger's default between version 6 and 7 is discussed in this thread, but it's such a big deal that it's worth its own thread. tl;dr: in v7 Cell Ranger changed how it produces the gene count matrix leading to a huge difference in results. 1/
The choice of whether to use Seurat or Scanpy for single-cell RNA-seq analysis typically comes down to a preference of R vs. Python. But do they produce the same results? In biorxiv.org/content/10.110… w/ @Josephmrich et al. we take a close look. The results are 👀 1/🧵
Come join us!
Stem Cell Research Assistant @NCNDgroup_KCL @VernonLab_KCL kcl.ac.uk/jobs/084933-st…
A great talk at #FOG2024 from Jon Mill @UniofExeter demonstrating the power of @nanopore sequencing, both for analysis of differential transcript expression in the brain and for detection of dna modifications across the genome - including disease-relevant 5hmC! #wymm
Over the moon to say I’m finally Dr MacCalman. Thank you so much to my supervisors @PsyEpigenetics @DrElisaDeFranco @aaron_r_j and to my wonderful examiners for an amazing viva @flanagan_se and Rachel Jennings
Recruiting multiple positions: 1) Lab post-doc - pancreatic differentiation and gene perturbation: jobs.exeter.ac.uk/hrpr_webrecrui… 2) Computational post-doc - stat models of footprinting and convolutional neural nets jobs.exeter.ac.uk/hrpr_webrecrui… 3) Lab technician jobs.exeter.ac.uk/hrpr_webrecrui… 4/
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