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Online Now: Decoding the spatial dynamics of tumor and immune cell interactions in solid cancers dlvr.it/TP7tPK
Now online! Systemic immune activity occurs during human immune system maturation dlvr.it/TNxLkJ
Integrated cell atlas and tumoroids chart #PancreaticCancer therapeutic targets biorxiv.org/content/10.110… Website for pancreatic cancer scRNA seq atlas: cells.ucsc.edu/?ds=pdac-atlas
For all commenting on this, there will be a flood of studies in this setting, some of which will satisfy both surg & rad oncs treatment parameters, so 5-10 years from now we will have an answer! #lcsm @DoctorJSpicer @DrewMoghanaki @gerryhanna @GavittWoodard @BrendonStilesMD
📢 #ESMO25 concomitant paper: results from the largest and most diverse international, multicenter, retrospective study on leptomeningeal metastases from #NSCLC @Nicmmzh126 bit.ly/3J5dlqk
Review of IL-1 family cytokines in inflammation and immunity - including, IL-1, IL-18, IL-33, IL-36, IL-37, IL-38, IL-1Ra, etc. Full read -- Good Reference!! buff.ly/jmT18rl
How exercise promotes the immune system vs cancer, working through a gut bacteria metabolite cell.com/cell/abstract/…
A very comprehensive effort to develop a single-cell atlas of human atherosclerosis based on 79 plaque samples from 3 vascular beds and >250K cells👇
A 2023 @SciImmunology Review contextualizes advances in CAR T cell #cancer immunotherapy, summarizing studies that explore the impact of metabolic stress on this treatment’s efficacy in the tumor microenvironment. Learn more: scim.ag/8o1 #ScienceMagArchives
Many cancer patients don’t know which symptoms are true emergencies or what steps to take when they arise. 🩺 Save this guide to recognize warning signs early—minutes matter.
#Throwback REVIEW | Sarah-Maria Fendt et al Metabolic heterogeneity in cancer nature.com/articles/s4225…
In oncology, clinical trials ARE the standard of care. Congrats to @Raffa_Casolino @WHO for a massive effort to organize global clinical trial data.. will help identify trends, gaps and regional disparities in the global cancer trial portfolio. who.int/publications/i…
🚨 Abstract submission deadline is approaching fast- September 15! 🚨 Join me and my co-chairs @TommyJohn00, @t_mitsudomi, @CelineMascaux, and @aaronctan in Tokyo, November 21–23, for the @IASLC 2025 Hot Topic Meeting #HT25. This is your chance to showcase your work on…
Join me and my co-chairs @TommyJohn00, @t_mitsudomi, @CelineMascaux, and @aaronctan in Tokyo this November 21-23 for the @IASLC 2025 Hot Topic Meeting #HT25. This meeting will bring together a global community of #researchers, #clinicians, and #innovators committed to…
Integrated single-cell and spatial transcriptomics uncover distinct cellular subtypes involved in neural invasion in pancreatic cancer dlvr.it/TMzL9K
KH815: TROP2 mAb (hRS7) conjugated to a topo1 inhibitor and an RNA polymerase II inhibitor Drug-E = Exatecan or an exatecan derivative Drug-T = Triptolide KH815 achieves DAR~7.5 (4+3.5) using cysteine and glycoside coupling technologies abstractsonline.com/pp8/#!/20273/p… #AACR25
First ever dual payload ADC in the clinic by Chengdu Kanghong Biotech! KH815, a dual-payload ADC targeting TROP2 Payloads: "Drug-T" and "Drug-E" And one of the two payloads is definitely a topoisomerase I inhibitor. clinicaltrials.gov/study/NCT06885…
Why does obesity change the pleasure of eating, the dopamine rush from hedonic foods? A neural circuit mechanism explanation @Nature nature.com/articles/s4158…
3.8 million lives saved. In the US, falling smoking rates led to 3.8 million fewer lung cancer deaths from 1970 to 2022. Prevention works. Public health matters. #lungcancer #cancer #publichealth #prevention #oncology @CACancerJournal @AmericanCancer @CDCgov @ASCO @WHO @IASLC
Join us for an enriching interactive #MTB webinar on MRD in #LungCancer on Wednesday March 19, 2025 being organised by Asian Thoracic Oncology Research Group (ATORG) Register: us02web.zoom.us/meeting/regist… @danieltanmd @mollylisc @HHorinouchi @drdaviddwlee @TonyMok9 @abcduke
I want to tell you a story about computers, creativity and awe! (1/N)🧵 Sydney Brenner once said in 2012 that “nobody has actually read the human genome. I mean, computers have processed the human genome, but we all know computers are stupid.” (This is a talk I gave last week..)
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